Gene name:
KDM4D (JHDM3D;JMJD2D) ;
Protein name:
Lysine-specific demethylase 4D ;
Alternative:
Jumonji domain-containing protein 2D ;JmjC domain-containing histone demethylation protein 3D ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.
Subcellular Location:
Nucleus
Protein Attributes:
50:
METMKSKANC | AQNPNCNIMI | FHPTKEEFND | FDKYIAYMES | QGAHRAGLAK |
100:
IIPPKEWKAR | ETYDNISEIL | IATPLQQVAS | GRAGVFTQYH | KKKKAMTVGE |
150:
YRHLANSKKY | QTPPHQNFED | LERKYWKNRI | YNSPIYGADI | SGSLFDENTK |
200:
QWNLGHLGTI | QDLLEKECGV | VIEGVNTPYL | YFGMWKTTFA | WHTEDMDLYS |
250:
INYLHLGEPK | TWYVVPPEHG | QRLERLAREL | FPGSSRGCGA | FLRHKVALIS |
300:
PTVLKENGIP | FNRITQEAGE | FMVTFPYGYH | AGFNHGFNCA | EAINFATPRW |
350:
IDYGKMASQC | SCGEARVTFS | MDAFVRILQP | ERYDLWKRGQ | DRAVVDHMEP |
400:
RVPASQELST | QKEVQLPRRA | ALGLRQLPSH | WARHSPWPMA | ARSGTRCHTL |
450:
VCSSLPRRSA | VSGTATQPRA | AAVHSSKKPS | STPSSTPGPS | AQIIHPSNGR |
500:
RGRGRPPQKL | RAQELTLQTP | AKRPLLAGTT | CTASGPEPEP | LPEDGALMDK |
523:
PVPLSPGLQH | PVKASGCSWA | PVP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
ELISA Kit for Human Lysine-specific demethylase 4D
ELISA Kit for Human Lysine-specific demethylase 4D
ELISA Kit for Human Lysine-specific demethylase 4D
CLIA Kit for Human Lysine-specific demethylase 4D
CLIA Kit for Human Lysine-specific demethylase 4D
CLIA Kit for Human Lysine-specific demethylase 4D
Polyclonal Antibody for Human Lysine-specific demethylase 4D
Polyclonal Antibody for Human Lysine-specific demethylase 4D
Polyclonal Antibody for Human Lysine-specific demethylase 4D
Monoclonal Antibody for Human Lysine-specific demethylase 4D
Monoclonal Antibody for Human Lysine-specific demethylase 4D
Monoclonal Antibody for Human Lysine-specific demethylase 4D
Protein for Human Lysine-specific demethylase 4D
Protein for Human Lysine-specific demethylase 4D
Protein for Human Lysine-specific demethylase 4D
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT GLN-408
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