Kng1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comKng1 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Kng1(Gene name) > Rat

Kng1 (Gene name),

Kininogen-1 (Protein name ), KNG1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Kng1(Kng);

Protein name:

Kininogen-1;

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

N/A

Function:

(1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.

Subcellular Location:

Secreted extracellular space

Protein Attributes:

Sequence length:

639

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

639:

FPEATSHKCP | GRPWKPVSRK | DPTIETTEFS | DFDLLDALS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.128333

KEGG:

rno:25087

Pfam:

PF00031

Uniprot:

P08934

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ELISA Kit for Rat Kininogen-1

Cat.:

E1805r

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96T

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ELISA Kit for Rat Kininogen-1

Cat.:

E1805b

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96T

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ELISA Kit for Rat Kininogen-1

Cat.:

E1805h

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96T

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ELISA Kit for Rat Kininogen-1

Cat.:

E1805m

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Packing:

96T

CLIA Kit for Rat Kininogen-1

Cat.:

U1805h

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Rat Kininogen-1

Cat.:

U1805b

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MSDS:

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Packing:

96T

CLIA Kit for Rat Kininogen-1

Cat.:

U1805r

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat Kininogen-1

Cat.:

U1805m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat Kininogen-1

Cat.:

P1805Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Kininogen-1

Cat.:

P1805Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Kininogen-1

Cat.:

P1805Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Kininogen-1

Protein for Rat Kininogen-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Differing expression patterns and evolution of the rat kininogen gene family."
Kitagawa H. , Kitamura N. , Hayashida H. , Miyata T. , Nakanishi S.
J. Biol. Chem.262:2190-2198(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS HMW AND LMW)
2.

"Primary structures of the mRNAs encoding the rat precursors for bradykinin and T-kinin. Structural relationship of kininogens with major acute phase protein and alpha 1-cysteine proteinase inhibitor."
Furuto-Kato S. , Matsumoto A. , Kitamura N. , Nakanishi S.
J. Biol. Chem.260:12054-12059(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM LMW)
3.

"Structure and expression of the genes for major acute phase alpha 1-protein (thiostatin) and kininogen in the rat."
Fung W.-P. , Schreiber G.
J. Biol. Chem.262:9298-9308(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-65
strain: Buffalo.
4.

"Differing utilization of homologous transcription initiation sites of rat K and T kininogen genes under inflammation condition."
Kageyama R. , Kitamura N. , Ohkubo H. , Nakanishi S.
J. Biol. Chem.262:2345-2351(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-41
strain: Wistar.
tissue: Liver.

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