Protein name:
Kynureninase ;
Alternative:
L-kynurenine hydrolase ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MEPSSLELPA | DTVQRIAAEL | KCHPTDERVA | LHLDEEDKLR | HFRECFYIPK |
100:
IQDLPPVDLS | LVNKDENAIY | FLGNSLGLQP | KMVKTYLEEE | LDKWAKIAAY |
150:
GHEVGKRPWI | TGDESIVGLM | KDIVGANEKE | IALMNALTVN | LHLLMLSFFK |
200:
PTPKRYKILL | EAKAFPSDHY | AIESQLQLHG | LNIEESMRMI | KPREGEETLR |
250:
IEDILEVIEK | EGDSIAVILF | SGVHFYTGQH | FNIPAITKAG | QAKGCYVGFD |
300:
LAHAVGNVEL | YLHDWGVDFA | CWCSYKYLNA | GAGGIAGAFI | HEKHAHTIKP |
350:
ALVGWFGHEL | STRFKMDNKL | QLIPGVCGFR | ISNPPILLVC | SLHASLEIFK |
400:
QATMKALRKK | SVLLTGYLEY | LIKHNYGKDK | AATKKPVVNI | ITPSHVEERG |
450:
CQLTITFSVP | NKDVFQELEK | RGVVCDKRNP | NGIRVAPVPL | YNSFHDVYKF |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Human Kynureninase
ELISA Kit for Human Kynureninase
ELISA Kit for Human Kynureninase
CLIA Kit for Human Kynureninase
CLIA Kit for Human Kynureninase
CLIA Kit for Human Kynureninase
Polyclonal Antibody for Human Kynureninase
Polyclonal Antibody for Human Kynureninase
Polyclonal Antibody for Human Kynureninase
Monoclonal Antibody for Human Kynureninase
Monoclonal Antibody for Human Kynureninase
Monoclonal Antibody for Human Kynureninase
Protein for Human Kynureninase
Protein for Human Kynureninase
Protein for Human Kynureninase
R&D Technical Data
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Precision
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Recovery
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Linearity
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Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);SUBCELLULAR LOCATION;TISSUE SPECIFICITY;CATALYTIC ACTIVITY;ENZYME REGULATION;BIOPHYSICOCHEMICAL PROPERTIES
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Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY;CATALYTIC ACTIVITY;ENZYME REGULATION;BIOPHYSICOCHEMICAL PROPERTIES
tissue :
Liver .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT GLU-412
tissue :
Synovium .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
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Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Cervix .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : MASS SPECTROMETRY;CATALYTIC ACTIVITY;BIOPHYSICOCHEMICAL PROPERTIES
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012)
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Cited for : X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) IN COMPLEX WITH PYRIDOXAL PHOSPHATE;HOMODIMERIZATION;CATALYTIC ACTIVITY;BIOPHYSICOCHEMICAL PROPERTIES
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT ALA-198;POSSIBLE INVOLVEMENT IN XANTHURENIC ACIDURIA