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Index > Protein center > LAG3(Gene name) > Human
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  • LAG3 (Gene name),
  • Lymphocyte activation gene 3 protein (Protein name ),  LAG3_HUMAN from NCBI database.
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  • Gene name:
    LAG3(FDC);
    Protein name:
    Lymphocyte activation gene 3 protein(LAG-3);
    Alternative:
    Protein FDC;
    CD:
    CD223;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Involved in lymphocyte activation. Binds to HLA class-II antigens.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    525
    Sequence:
    50:
    MWEAQFLGLL | FLQPLWVAPV | KPLQPGAEVP | VVWAQEGAPA | QLPCSPTIPL | 
    100:
    QDLSLLRRAG | VTWQHQPDSG | PPAAAPGHPL | APGPHPAAPS | SWGPRPRRYT | 
    150:
    VLSVGPGGLR | SGRLPLQPRV | QLDERGRQRG | DFSLWLRPAR | RADAGEYRAA | 
    200:
    VHLRDRALSC | RLRLRLGQAS | MTASPPGSLR | ASDWVILNCS | FSRPDRPASV | 
    250:
    HWFRNRGQGR | VPVRESPHHH | LAESFLFLPQ | VSPMDSGPWG | CILTYRDGFN | 
    300:
    VSIMYNLTVL | GLEPPTPLTV | YAGAGSRVGL | PCRLPAGVGT | RSFLTAKWTP | 
    350:
    PGGGPDLLVT | GDNGDFTLRL | EDVSQAQAGT | YTCHIHLQEQ | QLNATVTLAI | 
    400:
    ITVTPKSFGS | PGSLGKLLCE | VTPVSGQERF | VWSSLDTPSQ | RSFSGPWLEA | 
    450:
    QEAQLLSQPW | QCQLYQGERL | LGAAVYFTEL | SSPGAQRSGR | APGALPAGHL | 
    500:
    LLFLILGVLS | LLLLVTGAFG | FHLWRRQWRP | RRFSALEQGI | HPPQAQSKIE | 
    525:
    ELEQEPEPEP | EPEPEPEPEP | EPEQL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    String:
    MIM:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human LAG-3
    Cat.:
    E0914h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human LAG-3
    Cat.:
    E0914m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human LAG-3
    Cat.:
    E0914r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human LAG-3
    Cat.:
    U0914r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human LAG-3
    Cat.:
    U0914m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human LAG-3
    Cat.:
    U0914h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human LAG-3
    Cat.:
    P0914Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human LAG-3
    Cat.:
    P0914Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human LAG-3
    Cat.:
    P0914Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human LAG-3
    Monoclonal Antibody for Human LAG-3
    Monoclonal Antibody for Human LAG-3
    Protein for Human LAG-3
    Protein for Human LAG-3
    Protein for Human LAG-3

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "LAG-3, a novel lymphocyte activation gene closely related to CD4."
      Triebel F. , Jitsukawa S. , Baixeras E. , Roman-Roman S. , Genevee C. , Viegas-Pequignot E. , Hercend T.
      J. Exp. Med.171:1393-1405(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT THR-455
    2. 2.
      Triebel F.
      Submitted (2001-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION TO C-TERMINUS
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT THR-455
      tissue: Synovium.
    4. 4.
      "The finished DNA sequence of human chromosome 12."
      Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
      Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT THR-455
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Spleen.
    7. 7.
      "Characterization of the lymphocyte activation gene 3-encoded protein. A new ligand for human leukocyte antigen class II antigens."
      Baixeras E. , Huard B. , Miossec C. , Jitsukawa S. , Martin M. , Hercend T. , Auffray C. , Triebel F. , Piatier-Tonneau D.
      J. Exp. Med.176:327-337(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
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