Protein name:
Leucyl-cystinyl aminopeptidase (Cystinyl aminopeptidase) ;
Alternative:
Oxytocinase (OTase) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Homodimer. Binds tankyrases 1 and 2.
Function:
Release of an N-terminal amino acid, cleave before cysteine, leucine as well as other amino acids. Degrades peptide hormones such as oxytocin, vasopressin and angiotensin III, and plays a role in maintaining homeostasis during pregnancy. May be involved in the inactivation of neuronal peptides in the brain. Cleaves Met-enkephalin and dynorphin. Binds angiotensin IV and may be the angiotensin IV receptor in the brain.
Subcellular Location:
Cell membrane
Single-pass type II membrane protein
Endomembrane system
Single-pass type II membrane protein
Localized mainly in intracellular vesicles together with GLUT4. Relocalizes to the plasma membrane in response to insulin. The dileucine internalization motif and/or the interaction with tankyrases may be involved in intracellular sequestration.
Protein Attributes:
50:
MESFTNDRLQ | LPRNMIENSM | FEEEPDVVDL | AKEPCLHPLE | PDEVEYEPRG |
100:
SRLLVRGLGE | HEMDEDEEDY | ESSAKLLGMS | FMNRSSGLRN | SAAGYRQSPD |
150:
GTCSLPSART | LVICVFVIVV | AVSVIMVIYL | LPRCTFTKEG | CHKTNQSAEL |
200:
IQPVATNGKV | FPWAQIRLPT | AIIPLCYELS | LHPNLTSMTF | RGSVTISLQA |
250:
LQDTRDIILH | STGHNISRVT | FMSAVSSQEK | QVEILEYPYH | EQIAVVAPEP |
300:
LLTGHNYTLK | IEYSANISNS | YYGFYGITYT | DKSNEKKYFA | ATQFEPLAAR |
350:
SAFPCFDEPA | FKATFIIKIT | RNEHHTALSN | MPKKSSVPAE | EGLIQDEFSE |
400:
SVKMSTYLVA | FIVGEMRNLS | QDVNGTLVSV | YAVPEKIGQV | HHALDTTIKL |
450:
LEFYQTYFEI | QYPLKKLDLV | AIPDFEAGAM | ENWGLLTFRE | ETLLYDNATS |
500:
SVADRKLVTK | IIAHELAHQW | FGNLVTMQWW | NDLWLNEGFA | TFMEYFSVEK |
550:
IFKELNSYED | FLDARFKTMR | KDSLNSSHPI | SSSVQSSEQI | EEMFDSLSYF |
600:
KGASLLLMLK | SYLSEDVFRH | AVILYLHNHS | YAAIQSDDLW | DSFNEVTDKT |
650:
LDVKKMMKTW | TLQKGFPLVT | VQRKGTELLL | QQERFFLRMQ | PESQPSDTSH |
700:
LWHIPISYVT | DGRNYSEYRS | VSLLDKKSDV | INLTEQVQWV | KVNSNMTGYY |
750:
IVHYAHDDWT | ALINQLKRNP | YVLSDKDRAN | LINNIFELAG | LGKVPLRMAF |
800:
DLIDYLKNET | HTAPITEALF | QTNLIYNLLE | KLGHMDLSSR | LVARVHKLLQ |
850:
NQIQQQTWTD | EGTPSMRELR | SALLEFACAH | SLENCTTMAT | NLFDSWMASN |
900:
GTQSLPTDVM | VTVFKVGART | EKGWLFLFSM | YSSMGSEAEK | NKILEALASS |
950:
EDVHKLYWLM | KSSLDGDIIR | TQKLSLIIRT | VGRHFPGHLL | AWDFVKENWN |
1000:
KLVHKFHLGS | YTIQSIVAGS | THLFSTKTHL | SEVQAFFENQ | SEATLKLRCV |
1025:
QEALEVIQLN | IQWMVRNLKT | LSQWL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
ELISA Kit for Mouse Cystinyl aminopeptidase
ELISA Kit for Mouse Cystinyl aminopeptidase
ELISA Kit for Mouse Cystinyl aminopeptidase
CLIA Kit for Mouse Cystinyl aminopeptidase
CLIA Kit for Mouse Cystinyl aminopeptidase
CLIA Kit for Mouse Cystinyl aminopeptidase
Polyclonal Antibody for Mouse Cystinyl aminopeptidase
Polyclonal Antibody for Mouse Cystinyl aminopeptidase
Polyclonal Antibody for Mouse Cystinyl aminopeptidase
Monoclonal Antibody for Mouse Cystinyl aminopeptidase
Monoclonal Antibody for Mouse Cystinyl aminopeptidase
Monoclonal Antibody for Mouse Cystinyl aminopeptidase
Protein for Mouse Cystinyl aminopeptidase
Protein for Mouse Cystinyl aminopeptidase
Protein for Mouse Cystinyl aminopeptidase
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"The transcriptional landscape of the mammalian genome."
Carninci P.
,
Kasukawa T.
,
Katayama S.
,
Gough J.
,
Frith M.C.
,
Maeda N.
,
Oyama R.
,
Ravasi T.
,
Lenhard B.
,
Wells C.
,
Kodzius R.
,
Shimokawa K.
,
Bajic V.B.
,
Brenner S.E.
,
Batalov S.
,
Forrest A.R.
,
Zavolan M.
,
Davis M.J.
,
Wilming L.G.
,
Aidinis V.
,
Allen J.E.
,
Ambesi-Impiombato A.
,
Apweiler R.
,
Aturaliya R.N.
,
Bailey T.L.
,
Bansal M.
,
Baxter L.
,
Beisel K.W.
,
Bersano T.
,
Bono H.
,
Chalk A.M.
,
Chiu K.P.
,
Choudhary V.
,
Christoffels A.
,
Clutterbuck D.R.
,
Crowe M.L.
,
Dalla E.
,
Dalrymple B.P.
,
de Bono B.
,
Della Gatta G.
,
di Bernardo D.
,
Down T.
,
Engstrom P.
,
Fagiolini M.
,
Faulkner G.
,
Fletcher C.F.
,
Fukushima T.
,
Furuno M.
,
Futaki S.
,
Gariboldi M.
,
Georgii-Hemming P.
,
Gingeras T.R.
,
Gojobori T.
,
Green R.E.
,
Gustincich S.
,
Harbers M.
,
Hayashi Y.
,
Hensch T.K.
,
Hirokawa N.
,
Hill D.
,
Huminiecki L.
,
Iacono M.
,
Ikeo K.
,
Iwama A.
,
Ishikawa T.
,
Jakt M.
,
Kanapin A.
,
Katoh M.
,
Kawasawa Y.
,
Kelso J.
,
Kitamura H.
,
Kitano H.
,
Kollias G.
,
Krishnan S.P.
,
Kruger A.
,
Kummerfeld S.K.
,
Kurochkin I.V.
,
Lareau L.F.
,
Lazarevic D.
,
Lipovich L.
,
Liu J.
,
Liuni S.
,
McWilliam S.
,
Madan Babu M.
,
Madera M.
,
Marchionni L.
,
Matsuda H.
,
Matsuzawa S.
,
Miki H.
,
Mignone F.
,
Miyake S.
,
Morris K.
,
Mottagui-Tabar S.
,
Mulder N.
,
Nakano N.
,
Nakauchi H.
,
Ng P.
,
Nilsson R.
,
Nishiguchi S.
,
Nishikawa S.
,
Nori F.
,
Ohara O.
,
Okazaki Y.
,
Orlando V.
,
Pang K.C.
,
Pavan W.J.
,
Pavesi G.
,
Pesole G.
,
Petrovsky N.
,
Piazza S.
,
Reed J.
,
Reid J.F.
,
Ring B.Z.
,
Ringwald M.
,
Rost B.
,
Ruan Y.
,
Salzberg S.L.
,
Sandelin A.
,
Schneider C.
,
Schoenbach C.
,
Sekiguchi K.
,
Semple C.A.
,
Seno S.
,
Sessa L.
,
Sheng Y.
,
Shibata Y.
,
Shimada H.
,
Shimada K.
,
Silva D.
,
Sinclair B.
,
Sperling S.
,
Stupka E.
,
Sugiura K.
,
Sultana R.
,
Takenaka Y.
,
Taki K.
,
Tammoja K.
,
Tan S.L.
,
Tang S.
,
Taylor M.S.
,
Tegner J.
,
Teichmann S.A.
,
Ueda H.R.
,
van Nimwegen E.
,
Verardo R.
,
Wei C.L.
,
Yagi K.
,
Yamanishi H.
,
Zabarovsky E.
,
Zhu S.
,
Zimmer A.
,
Hide W.
,
Bult C.
,
Grimmond S.M.
,
Teasdale R.D.
,
Liu E.T.
,
Brusic V.
,
Quackenbush J.
,
Wahlestedt C.
,
Mattick J.S.
,
Hume D.A.
,
Kai C.
,
Sasaki D.
,
Tomaru Y.
,
Fukuda S.
,
Kanamori-Katayama M.
,
Suzuki M.
,
Aoki J.
,
Arakawa T.
,
Iida J.
,
Imamura K.
,
Itoh M.
,
Kato T.
,
Kawaji H.
,
Kawagashira N.
,
Kawashima T.
,
Kojima M.
,
Kondo S.
,
Konno H.
,
Nakano K.
,
Ninomiya N.
,
Nishio T.
,
Okada M.
,
Plessy C.
,
Shibata K.
,
Shiraki T.
,
Suzuki S.
,
Tagami M.
,
Waki K.
,
Watahiki A.
,
Okamura-Oho Y.
,
Suzuki H.
,
Kawai J.
,
Hayashizaki Y.
more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Skin .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-70; SER-80 AND SER-91;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-447 AND ASN-682