Protein name:
Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase;LAL) ;
Alternative:
Lipase A ;Cholesteryl esterase ;Sterol esterase ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation.
Subcellular Location:
Lysosome
Protein Attributes:
50:
MQLQGLVFVF | TIGILLSRVP | TGTVSAVDPE | VNMNVTEIIM | RWGYPGEEHS |
100:
VLTGDGYILS | IHRIPRGRKN | HFGKGPRPVV | YLQHGLLADS | SNWVTNIDNS |
150:
SLGFLLADAG | FDVWMGNSRG | NTWSLKHKTL | SVSQDEFWAF | SFDEMAKYDL |
200:
PASINYILNK | TGQEQIYYVG | HSQGCTIGFI | AFSQMPELAK | KIKMFLVLAP |
250:
VLSLNFASGP | LLQLGRLPDP | LLKDMFGQKQ | FLPQSAMLKW | LSIHVCTHVI |
300:
MKELCANVFF | LLCGFNEKNL | NMSRVDVYTT | HCPAGTSVQN | MLHWGQVFKY |
350:
RKLQAFDWGS | SEKNYFHYNQ | SFPPSYNIKN | MRLPTALWSG | GRDWLADIND |
397:
ITILLTQIPK | LVYHKNIPEW | DHLDFIWGLD | APWKLYDEII | SLMKKYQ
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
ELISA Kit for Mouse Acid cholesteryl ester hydrolase
ELISA Kit for Mouse Acid cholesteryl ester hydrolase
ELISA Kit for Mouse Acid cholesteryl ester hydrolase
CLIA Kit for Mouse Acid cholesteryl ester hydrolase
CLIA Kit for Mouse Acid cholesteryl ester hydrolase
CLIA Kit for Mouse Acid cholesteryl ester hydrolase
Polyclonal Antibody for Mouse Acid cholesteryl ester hydrolase
Polyclonal Antibody for Mouse Acid cholesteryl ester hydrolase
Polyclonal Antibody for Mouse Acid cholesteryl ester hydrolase
Monoclonal Antibody for Mouse Acid cholesteryl ester hydrolase
Monoclonal Antibody for Mouse Acid cholesteryl ester hydrolase
Monoclonal Antibody for Mouse Acid cholesteryl ester hydrolase
Protein for Mouse Acid cholesteryl ester hydrolase
Protein for Mouse Acid cholesteryl ester hydrolase
Protein for Mouse Acid cholesteryl ester hydrolase
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
C57BL/6 X CBA .
tissue :
Liver .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
strain :
NOD .
tissue :
Bone marrow .
tissue :
Thymus .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]