Gene name:
TRIM71 (LIN41) ;
Protein name:
E3 ubiquitin-protein ligase TRIM71 ;
Alternative:
Tripartite motif-containing protein 71 ;Protein lin-41 homolog ;
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Interacts (via NHL repeats) with AGO2. Interacts with SHCBP1; leading to enhance its stability.
Function:
E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance. Binds to miRNAs and associates with AGO2, participating in post-transcriptional repression of transcripts such as CDKN1A. Facilitates the G1-S transition to promote rapid embryonic stem cell self-renewal by repressing CDKN1A expression. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development: positively regulates FGF signaling by controlling the stability of SHCBP1.
Subcellular Location:
Cytoplasm
P-body
Protein Attributes:
50:
MASFPETDFQ | ICLLCKEMCG | SPAPLSSNSS | ASSSSSQTST | SSGGGGGGPG |
100:
AAARRLHVLP | CLAFCRPCLE | AHRGGAPGEP | LKLRCPVCDQ | KVVLAEAAGM |
150:
DARPSSAFLL | SNLLDAVVAT | ADEPPPKNGR | AGAAAGAGGH | GSNHRHHAHH |
200:
AHPRAAASAP | PPPLPPAPPP | PAPPRSAPGG | PAGSPSALLL | RRPHGCSSCD |
250:
EGNAASSRCL | DCQEHLCDNC | VRAHQRVRLT | KDHYIERGPP | GPAAAAAAAA |
300:
AQQLGLGPPF | PGAPFSLLSV | FPERLGFCQH | HDDEVLHLYC | DTCSVPICRE |
350:
CTVGRHGGHS | FVYLQEALQD | SRALTIQLLA | DAQQGRQAIQ | LSIEQAQTVA |
400:
EQVEMKAKVV | QSEVKAVTAR | HKKALEEREC | ELLWKVEKIR | QVKAKSLYLQ |
450:
VEKLRQNLNK | LESTISAVQQ | VLEEGRALDI | LLARDRMLAQ | VQELKTVRSL |
500:
LQPQEDDRVM | FTPPDQALYL | AIKSFGFVSS | GAFAPLTKAT | GDGLKRALQG |
550:
KVASFTVIGY | DHDGEPRLSG | GDLMSAVVLG | PDGNLFGAEV | SDQQNGTYVV |
600:
SYRPQLEGEH | LVSVTLCNQH | IENSPFKVVV | KSGRSYVGIG | LPGLSFGSEG |
650:
DSDGKLCRPW | GVSVDKEGYI | VVADRSNNRI | QVFKPCGAFH | HKFGTLGSRP |
700:
GQFDRPAGVA | CDASRRIVVA | DKDNHRIQIF | TFEGQFLLKF | GEKGTKNGQF |
750:
NYPWDVAVNS | EGKILVSDTR | NHRIQLFGPD | GVFLNKYGFE | GALWKHFDSP |
800:
RGVAFNHEGH | LVVTDFNNHR | LLVIHPDCQS | ARFLGSEGTG | NGQFLRPQGV |
850:
AVDQEGRIIV | ADSRNHRVQM | FESNGSFLCK | FGAQGSGFGQ | MDRPSGIAVT |
868:
PDGMIVVVDF | GNNRILIF
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Bovine
Chicken
Human
Rat
ELISA Kit for Bovine E3 ubiquitin-protein ligase TRIM71
ELISA Kit for Bovine E3 ubiquitin-protein ligase TRIM71
ELISA Kit for Bovine E3 ubiquitin-protein ligase TRIM71
ELISA Kit for Bovine E3 ubiquitin-protein ligase TRIM71
ELISA Kit for Bovine E3 ubiquitin-protein ligase TRIM71
CLIA Kit for Bovine E3 ubiquitin-protein ligase TRIM71
CLIA Kit for Bovine E3 ubiquitin-protein ligase TRIM71
CLIA Kit for Bovine E3 ubiquitin-protein ligase TRIM71
CLIA Kit for Bovine E3 ubiquitin-protein ligase TRIM71
CLIA Kit for Bovine E3 ubiquitin-protein ligase TRIM71
Polyclonal Antibody for Bovine E3 ubiquitin-protein ligase TRIM71
Polyclonal Antibody for Bovine E3 ubiquitin-protein ligase TRIM71
Polyclonal Antibody for Bovine E3 ubiquitin-protein ligase TRIM71
Polyclonal Antibody for Bovine E3 ubiquitin-protein ligase TRIM71
Polyclonal Antibody for Bovine E3 ubiquitin-protein ligase TRIM71
Monoclonal Antibody for Bovine E3 ubiquitin-protein ligase TRIM71
Monoclonal Antibody for Bovine E3 ubiquitin-protein ligase TRIM71
Monoclonal Antibody for Bovine E3 ubiquitin-protein ligase TRIM71
Monoclonal Antibody for Bovine E3 ubiquitin-protein ligase TRIM71
Monoclonal Antibody for Bovine E3 ubiquitin-protein ligase TRIM71
Protein for Bovine E3 ubiquitin-protein ligase TRIM71
Protein for Bovine E3 ubiquitin-protein ligase TRIM71
Protein for Bovine E3 ubiquitin-protein ligase TRIM71
Protein for Bovine E3 ubiquitin-protein ligase TRIM71
Protein for Bovine E3 ubiquitin-protein ligase TRIM71
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"A whole-genome assembly of the domestic cow, Bos taurus."
Zimin A.V.
,
Delcher A.L.
,
Florea L.
,
Kelley D.R.
,
Schatz M.C.
,
Puiu D.
,
Hanrahan F.
,
Pertea G.
,
Van Tassell C.P.
,
Sonstegard T.S.
,
Marcais G.
,
Roberts M.
,
Subramanian P.
,
Yorke J.A.
,
Salzberg S.L.
Genome Biol.10:R42.01-R42.10(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
Hereford .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 476-725