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Index > Protein center > LOXL2(Gene name) > Chicken
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  • LOXL2 (Gene name),
  • Lysyl oxidase homolog 2 (Protein name ),  LOXL2_CHICK from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    LOXL2;
    Protein name:
    Lysyl oxidase homolog 2;
    Alternative:
    Lysyl oxidase-like protein 2;
    Organism:
    Chicken (Gallus gallus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and probably specifically mediates deamination of histone H3. Involved in epithelial to mesenchymal transition (EMT) and participates in repression of E-cadherin, probably by mediating deamination of histone H3. Acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation.
    Subcellular Location:
    Secreted Extracellular space Extracellular matrix Basement membrane Nucleus Chromosome Associated with chromatin (By similarity). It is unclear how LOXL2 is nuclear: it contains a clear signal sequence and is predicted to localize in the extracellular medium. However, different reports confirmed the intracellular location and its key role in transcription regulation.
    Protein Attributes:
    Sequence length:
    774
    Sequence:
    50:
    MEGFLGFNHN | HCFIVLFFVS | LSLAQYEHWP | YLPGYPEPPP | QVYQPPRRPA | 
    100:
    DVPKIQLRLA | GQKRKHNEGR | VEVFYNGEWG | TVCDDDFSIH | AAHVICRELG | 
    150:
    YVEAVSWLPS | SKYGKGEGKI | WMDNVHCNGK | EATLAACTSN | GWGVTDCKHT | 
    200:
    EDVGVVCSEK | RIPGFKFDNS | LLNQIENMNI | QVEDIRIRPI | LATYRKRVPV | 
    250:
    TEGYVEVKDE | GTWKQICDKH | WTMKNSRVVC | GMFGFPSERK | YNTKVYKMFA | 
    300:
    SRRKQHYWAY | SMDCTGNEAH | ISSCKLGNHL | NVDTEKNATC | DNGMPAVASC | 
    350:
    VPGRAFAPSS | HSGFRKAFRQ | EQPLVRLKGG | ANTGEGRVEV | LKNGEWGTVC | 
    400:
    DDNWNLVSAS | VVCRELGFGS | AKEAITGARL | GQGMGPIHLN | EIDCTGFEKS | 
    450:
    LTDCKFNMES | QGCNHEEDAA | VRCNVPAMGF | QNQLRLVGGR | NPYEGRVEVL | 
    500:
    AERNGTLRWG | TVCSQGWSTV | EAMVVCRQLG | LGFASHAFQE | TWYWHGDVSA | 
    550:
    DSVVMSGVKC | SGTEMSLAHC | RHDGADVSCP | RGGGRFGAGV | SCSETAPDLV | 
    600:
    LNAELVEQTA | YLEDRPMFML | QCAQEENCLA | SSAVNTSVTS | GYRRLLRFSS | 
    650:
    QIHNNGQSDF | RPKNGRHAWV | WHDCHRHYHS | MEVFTHYDLL | NLNGTKVAEG | 
    700:
    HKASFCLEDT | ECEADVQKQY | ECANFGEQGI | TVGCWDVYRH | DIDCQWIDIT | 
    750:
    DVPPGDYLFQ | VVINPNYEVA | ESDYSNNVMK | CRSRYDGQRI | WMYNSVHNGA | 
    774:
    NQDGDTEERF | SAYWKLGNSI | LFSR
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Chicken Lysyl oxidase homolog 2
    Cat.:
    E14939h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Chicken Lysyl oxidase homolog 2
    MSDS:
    Please sign in first.
    ELISA Kit for Chicken Lysyl oxidase homolog 2
    MSDS:
    Please sign in first.
    ELISA Kit for Chicken Lysyl oxidase homolog 2
    Cat.:
    E14939r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Chicken Lysyl oxidase homolog 2
    Cat.:
    E14939m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Chicken Lysyl oxidase homolog 2
    Cat.:
    U14939h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken Lysyl oxidase homolog 2
    MSDS:
    Please sign in first.
    CLIA Kit for Chicken Lysyl oxidase homolog 2
    MSDS:
    Please sign in first.
    CLIA Kit for Chicken Lysyl oxidase homolog 2
    MSDS:
    Please sign in first.
    CLIA Kit for Chicken Lysyl oxidase homolog 2
    Cat.:
    U14939m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Chicken Lysyl oxidase homolog 2
    Polyclonal Antibody for Chicken Lysyl oxidase homolog 2
    Polyclonal Antibody for Chicken Lysyl oxidase homolog 2
    Polyclonal Antibody for Chicken Lysyl oxidase homolog 2
    Polyclonal Antibody for Chicken Lysyl oxidase homolog 2
    Monoclonal Antibody for Chicken Lysyl oxidase homolog 2
    Monoclonal Antibody for Chicken Lysyl oxidase homolog 2
    Monoclonal Antibody for Chicken Lysyl oxidase homolog 2
    Monoclonal Antibody for Chicken Lysyl oxidase homolog 2
    Monoclonal Antibody for Chicken Lysyl oxidase homolog 2
    Protein for Chicken Lysyl oxidase homolog 2
    Protein for Chicken Lysyl oxidase homolog 2
    Protein for Chicken Lysyl oxidase homolog 2
    Protein for Chicken Lysyl oxidase homolog 2
    Protein for Chicken Lysyl oxidase homolog 2

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    References
    1. 1.
      "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution."
      Hillier L.W. , Miller W. , Birney E. , Warren W. , Hardison R.C. , Ponting C.P. , Bork P. , Burt D.W. , Groenen M.A.M. , Delany M.E. , Dodgson J.B. , Chinwalla A.T. , Cliften P.F. , Clifton S.W. , Delehaunty K.D. , Fronick C. , Fulton R.S. , Graves T.A. , more...
      Nature432:695-716(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Red jungle fowl.
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