Protein name:
Mitogen-activated protein kinase kinase kinase 13 ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Homodimer; forms dimers through the leucine-zipper motif. Interacts with the C-terminus of MAPK8IP1 through the kinase catalytic domain. Binds PRDX3. Associates with the IKK complex through the kinase domain.
Function:
Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.
Subcellular Location:
Cytoplasm
Membrane
Peripheral membrane protein
Protein Attributes:
50:
MANPQEHLSC | SSSPRLPLSE | NKTFNGLQDD | LAPMGSHASP | KLLKDQQEKG |
100:
MVQTELAEGT | NSPITTTVLT | SISEDSRDQF | ENSVLQLREQ | DESEMAMSHG |
150:
NSNTVDGEGT | SGTEDIKIQF | SRSGSGSGGF | LEGLFGCLRP | VWNIIGKAYS |
200:
TDYKLQQQDT | WEVPFEEISE | LQWLGSGAQG | AVFLGKFRAE | EVAIKKVREQ |
250:
NETDIKHLRK | LKHPNIIAFK | GVCTQAPCYC | IIMEYCAHGQ | LYEVLRAGRK |
300:
ITPRLLVDWS | TGIASGMNYL | HLHKIIHRDL | KSPNVLVTHT | DAVKISDFGT |
350:
SKELSDKSTK | MSFAGTVAWM | APEVIRNEPV | SEKVDIWSFG | VVLWELLTGE |
400:
IPYKDVDSSA | IIWGVGSNSL | HLPVPSTCPD | GFKILMKQTW | QSKTRNRPSF |
450:
RQTLMHLDIA | SADVLATPQE | TYFKSQAEWR | EEVKKHFEKI | KSEGTCIHRL |
500:
DEELIRRRRE | ELRHALDIRE | HYERKLERAN | NLYMELSAIM | LQLEMREKEL |
550:
IKREQAVEKK | YPGTYKRHPV | RPIIHPNAME | KLMKRKGMPH | RPGMQAKRPD |
600:
LLRSEGIPSV | EVAPTASPLS | GSPKLSSSSS | KSRYRSKPRH | RRGNSRGSHG |
650:
DFAAILKNQP | AQEDSPHPTS | LHQAEPQYPS | SQHHNLLQQQ | YQQPPPAMSQ |
700:
SHHPRLNMHG | QDIATCPNNL | RYFGPAAALR | SPLSNHSQRQ | MPGSSPDLIS |
750:
TAMAADCWRS | SEPDKGQAGP | WGCCQADPYD | PCLQCRPEQH | GSLDVPSAKP |
800:
VGRSPSLFKP | PAHNPLLENA | QGSEKMEENE | FSGYRSASSL | GASHHITPPV |
850:
LPRKTRPLQK | SGDDSSEEEE | GEVDSEVEFP | RRQRPHRCIS | SCQSYSTFSS |
900:
ENFSVSDGEE | GNTSDHSNSP | DELADKLEDH | LAEKLDDLLS | QTPEIPIEIS |
950:
SHSDGLSDKE | CAVRRVKTQM | SLGKLCAEER | GYENPMQFEE | SDCDSSDGEC |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Bovine
ELISA Kit for Bovine Mitogen-activated protein kinase kinase kinase 13
ELISA Kit for Bovine Mitogen-activated protein kinase kinase kinase 13
ELISA Kit for Bovine Mitogen-activated protein kinase kinase kinase 13
CLIA Kit for Bovine Mitogen-activated protein kinase kinase kinase 13
CLIA Kit for Bovine Mitogen-activated protein kinase kinase kinase 13
CLIA Kit for Bovine Mitogen-activated protein kinase kinase kinase 13
Polyclonal Antibody for Bovine Mitogen-activated protein kinase kinase kinase 13
Polyclonal Antibody for Bovine Mitogen-activated protein kinase kinase kinase 13
Polyclonal Antibody for Bovine Mitogen-activated protein kinase kinase kinase 13
Monoclonal Antibody for Bovine Mitogen-activated protein kinase kinase kinase 13
Monoclonal Antibody for Bovine Mitogen-activated protein kinase kinase kinase 13
Monoclonal Antibody for Bovine Mitogen-activated protein kinase kinase kinase 13
Protein for Bovine Mitogen-activated protein kinase kinase kinase 13
Protein for Bovine Mitogen-activated protein kinase kinase kinase 13
Protein for Bovine Mitogen-activated protein kinase kinase kinase 13
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Hereford .
tissue :
Fetal liver .