Protein name:
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase ;
Alternative:
ER mannosidase 1 (ERMan1) ;ER alpha-1,2-mannosidase ;Mannosidase alpha class 1B member 1 ;Man9GlcNAc2-specific-processing alpha-mannosidase ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2), but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man(5-6)GlcNAc(2).
Subcellular Location:
Endoplasmic reticulum membrane
Single-pass type II membrane protein
Protein Attributes:
50:
MYPPPAPPPA | PHRDFISVTL | SLGESYDNSK | SRRRRSCWRK | WKQLSRLQRN |
100:
VILFVLGFLI | LCGFLYSLHT | ADQWKALSGR | PAEVEKMKQE | VLPVLPAPQK |
150:
ESAEQEGFAD | ILSQKRQRHF | RRGPPHLQIR | PPNTVSKDGM | QDDAKEREAA |
200:
LGKAQQEENT | QRTVISWRGA | VIEPEQATEL | PYKRAEASIK | PLVLASKIWK |
250:
EPAPPNERQK | GVIEAFLHAW | KGYQKFAWGH | DELKPVSKTF | SEWFGLGLTL |
300:
IDALDTMWIL | GLKQEFKQAR | KWVSENLDFQ | KNVDVNLFES | TIRILGGLLS |
350:
TYHLSGDSLF | LTKAEDFGKR | LMPAFTTPSK | IPYSDVNIGT | GFAHSPQWTS |
400:
DSTVAEVTSI | QLEFRELSRL | TGIKKFQEAV | EEVTKHIHSL | SGKKDGLVPM |
450:
FINTNSGLFT | HPGVFTLGAR | ADSYYEYLLK | QWIQGGKKET | QLLEDYVKAI |
500:
EGIKAHLLRQ | SQPRKLTFVG | ELAHGRFSAK | MDHLVCFLPG | TLALGVHHGL |
550:
PADHMDLARA | LMETCYQMNQ | QMETGLSPEI | AHFNMYPRAD | HKDVEVKPAD |
600:
RHNLLRPETV | ESLFYLYRVT | RDRKYQDWGW | EILQSFNKYT | RVPSGGYSSI |
650:
NNVQNSHKPE | PRDKMESFFV | GETLKYLYLL | FSDDLELLSL | DSCVFNTEAH |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
ELISA Kit for Mouse Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
ELISA Kit for Mouse Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
ELISA Kit for Mouse Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
CLIA Kit for Mouse Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
CLIA Kit for Mouse Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
CLIA Kit for Mouse Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
Polyclonal Antibody for Mouse Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
Polyclonal Antibody for Mouse Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
Polyclonal Antibody for Mouse Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
Monoclonal Antibody for Mouse Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
Monoclonal Antibody for Mouse Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
Monoclonal Antibody for Mouse Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
Protein for Mouse Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
Protein for Mouse Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
Protein for Mouse Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
,
Goodstadt L.
,
Hillier L.W.
,
Zody M.C.
,
Goldstein S.
,
She X.
,
Bult C.J.
,
Agarwala R.
,
Cherry J.L.
,
DiCuccio M.
,
Hlavina W.
,
Kapustin Y.
,
Meric P.
,
Maglott D.
,
Birtle Z.
,
Marques A.C.
,
Graves T.
,
Zhou S.
,
Teague B.
,
Potamousis K.
,
Churas C.
,
Place M.
,
Herschleb J.
,
Runnheim R.
,
Forrest D.
,
Amos-Landgraf J.
,
Schwartz D.C.
,
Cheng Z.
,
Lindblad-Toh K.
,
Eichler E.E.
,
Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .