Language:
  
[Sign in] [Register]   

EIAab logo

Index > Protein center > MAGI1(Gene name) > Human
  • Add your favorite
  • MAGI1 (Gene name),
  • Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (Protein name ),  MAGI1_HUMAN from NCBI database.
  • top
  • Come back to page head.
  • |
  • General Annotation
  • |
  • Antigen Annotation
  • |
  • 3D
  • |
  • Predicted Eptitope
  • |
  • Vaild Sequence
  • |
  • Related Databases
  • |
  • Feedback
  • Gene name:
    MAGI1(AIP3;BAIAP1;BAP1;TNRC19);
    Protein name:
    Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1;
    Alternative:
    BAI1-associated protein 1(BAP-1);Atrophin-1-interacting protein 3(AIP-3);Trinucleotide repeat-containing gene 19 protein;Membrane-associated guanylate kinase inverted 1(MAGI-1);WW domain-containing protein 3(WWP3);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts through its WW 2 domain with SYNPO and through its PDZ 5 domain with ACTN4. Interacts with cytoplasmic domain of BAI1. Interacts via its WW domains with DRPLA. Interacts with ESAM, LRP2 and CXADR. May interact with CTNNB1. Interacts through its PDZ 1 domain with NET1 (By similarity). Interacts with ACCN3 and AMOT. Interacts with FCHSD2. Interacts with IGSF5/JAM4 and through its PDZ 2 and 3 domains with NPHS1 forming a tripartite complex (By similarity). Interacts with DDN.
    Function:
    May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ACCN3 currents by modulating its expression at the cell surface.
    Subcellular Location:
    Cell junction tight junction Cell membrane Peripheral membrane protein Localizes to epithelial cells tight junctions.
    Protein Attributes:
    Sequence length:
    1491
    Sequence:
    50:
    MSKVIQKKNH | WTSRVHECTV | KRGPQGELGV | TVLGGAEHGE | FPYVGAVAAV | 
    100:
    EAAGLPGGGE | GPRLGEGELL | LEVQGVRVSG | LPRYDVLGVI | DSCKEAVTFK | 
    150:
    AVRQGGRLNK | DLRHFLNQRF | QKGSPDHELQ | QTIRDNLYRH | AVPCTTRSPR | 
    200:
    EGEVPGVDYN | FLTVKEFLDL | EQSGTLLEVG | TYEGNYYGTP | KPPSQPVSGK | 
    250:
    VITTDALHSL | QSGSKQSTPK | RTKSYNDMQN | AGIVHAENEE | EDDVPEMNSS | 
    300:
    FTADSGEQEE | HTLQETALPP | VNSSIIAAPI | TDPSQKFPQY | LPLSAEDNLG | 
    350:
    PLPENWEMAY | TENGEVYFID | HNTKTTSWLD | PRCLNKQQKP | LEECEDDEGV | 
    400:
    HTEELDSELE | LPAGWEKIED | PVYGIYYVDH | INRKTQYENP | VLEAKRKKQL | 
    450:
    EQQQQQQQQQ | QQQQQQQQQQ | QTEEWTEDHS | ALVPPVIPNH | PPSNPEPARE | 
    500:
    VPLQGKPFFT | RNPSELKGKF | IHTKLRKSSR | GFGFTVVGGD | EPDEFLQIKS | 
    550:
    LVLDGPAALD | GKMETGDVIV | SVNDTCVLGH | THAQVVKIFQ | SIPIGASVDL | 
    600:
    ELCRGYPLPF | DPDDPNTSLV | TSVAILDKEP | IIVNGQETYD | SPASHSSKTG | 
    650:
    KVNGMKDARP | SSPADVASNS | SHGYPNDTVS | LASSIATQPE | LITVHIVKGP | 
    700:
    MGFGFTIADS | PGGGGQRVKQ | IVDSPRCRGL | KEGDLIVEVN | KKNVQALTHN | 
    750:
    QVVDMLVECP | KGSEVTLLVQ | RGGLPVPKKS | PKSQPLERKD | SQNSSQHSVS | 
    800:
    SHRSLHTASP | SHSTQVLPEF | PPAEAQAPDQ | TDSSGQKKPD | PFKIWAQSRS | 
    850:
    MYENRPMSPS | PASGLSKGER | EREINSTNFG | ECPIPDYQEQ | DIFLWRKETG | 
    900:
    FGFRILGGNE | PGEPIYIGHI | VPLGAADTDG | RLRSGDELIC | VDGTPVIGKS | 
    950:
    HQLVVQLMQQ | AAKQGHVNLT | VRRKVVFAVP | KTENEVPSPA | SSHHSSNQPA | 
    1000:
    SLTEEKRTPQ | GSQNSLNTVS | SGSGSTSGIG | SGGGGGSGVV | STVVQPYDVE | 
    1050:
    IRRGENEGFG | FVIVSSVSRP | EAGTTFAGNA | CVAMPHKIGR | IIEGSPADRC | 
    1100:
    GKLKVGDRIL | AVNGCSITNK | SHSDIVNLIK | EAGNTVTLRI | IPGDESSNAT | 
    1150:
    LLTNAEKIAT | ITTTHTPSQQ | GTQETRNTTK | PKQESQFEFK | APQATQEQDF | 
    1200:
    YTVELERGAK | GFGFSLRGGR | EYNMDLYVLR | LAEDGPAERC | GKMRIGDEIL | 
    1250:
    EINGETTKNM | KHSRAIELIK | NGGRRVRLFL | KRGDGSVPEY | DPSSDRHGPA | 
    1300:
    TGPQGVPEVR | AGPDRRQHPS | LESSYPPDLH | KSSPHGEKRA | HARDPKGSRE | 
    1350:
    YSRQPNEHHT | WNGTSRKPDS | GACRPKDRAP | EGRRDAQAER | AAAANGPKRR | 
    1400:
    SPEKRREGTR | SADNTLERRE | KHEKRRDVSP | ERRRERSPTR | RRDGSPSRRR | 
    1450:
    RSLERLLEQR | RSPERRRGGS | PERRAKSTDR | RRARSPERRR | ERSLDKRNRE | 
    1491:
    DRASHREREE | ANLKQDAGRS | SRHPPEQRRR | PYKECSTDLS | I
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    Pfam:
    MIM:
    String:
    UniGene:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
    ELISA Kit for Human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
    ELISA Kit for Human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
    CLIA Kit for Human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
    CLIA Kit for Human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
    CLIA Kit for Human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
    Polyclonal Antibody for Human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
    Polyclonal Antibody for Human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
    Polyclonal Antibody for Human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
    Monoclonal Antibody for Human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
    Monoclonal Antibody for Human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
    Monoclonal Antibody for Human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
    Protein for Human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
    Protein for Human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
    Protein for Human Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Cloning and characterization of BAI-associated protein 1: a PDZ domain-containing protein that interacts with BAI1."
      Shiratsuchi T. , Futamura M. , Oda K. , Nishimori H. , Nakamura Y. , Tokino T.
      Biochem. Biophys. Res. Commun.247:597-604(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);TISSUE SPECIFICITY;INTERACTION WITH BAI1
      tissue: Brain.
    2. 2.
      "MAGI-1: a widely expressed, alternatively spliced tight junction protein."
      Laura R.P. , Ross S. , Koeppen H. , Lasky L.A.
      Exp. Cell Res.275:155-170(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2; 4 AND 5);ALTERNATIVE SPLICING (ISOFORMS 6 AND 7);SUBCELLULAR LOCATION;PHOSPHORYLATION;TISSUE SPECIFICITY
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
      tissue: Brain.
    4. 4.
      "The DNA sequence, annotation and analysis of human chromosome 3."
      Muzny D.M. , Scherer S.E. , Kaul R. , Wang J. , Yu J. , Sudbrak R. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , more...
      Nature440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins."
      Wood J.D. , Yuan J. , Margolis R.L. , Colomer V. , Duan K. , Kushi J. , Kaminsky Z. , Kleiderlein J.J. Jr. , Sharp A.H. , Ross C.A.
      Mol. Cell. Neurosci.11:149-160(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 150-826 (ISOFORMS 1/3);TISSUE SPECIFICITY;INTERACTION WITH DRPLA
    6. 6.
      "Identification of novel human WW domain-containing proteins by cloning of ligand targets."
      Pirozzi G. , McConnell S.J. , Uveges A.J. , Carter J.M. , Sparks A.B. , Kay B.K. , Fowlkes D.M.
      J. Biol. Chem.272:14611-14616(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 152-371
    7. 7.
      "Membrane-associated guanylate kinase with inverted orientation (MAGI)-1/brain angiogenesis inhibitor 1-associated protein (BAP1) as a scaffolding molecule for Rap small G protein GDP/GTP exchange protein at tight junctions."
      Mino A. , Ohtsuka T. , Inoue E. , Takai Y.
      Genes Cells5:1009-1016(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RAPGEF2
    8. 8.
      "Interaction of two actin-binding proteins, synaptopodin and alpha-actinin-4, with the tight junction protein MAGI-1."
      Patrie K.M. , Drescher A.J. , Welihinda A. , Mundel P. , Margolis B.
      J. Biol. Chem.277:30183-30190(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SYNPO AND ACTN4
    9. 9.
      "JAM4, a junctional cell adhesion molecule interacting with a tight junction protein, MAGI-1."
      Hirabayashi S. , Tajima M. , Yao I. , Nishimura W. , Mori H. , Hata Y.
      Mol. Cell. Biol.23:4267-4282(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH IGSF5
    10. 10.
      "Carom: a novel membrane-associated guanylate kinase-interacting protein with two SH3 domains."
      Ohno H. , Hirabayashi S. , Kansaku A. , Yao I. , Tajima M. , Nishimura W. , Ohnishi H. , Mashima H. , Fujita T. , Omata M. , Hata Y.
      Oncogene22:8422-8431(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FCHSD2
    11. 11.
      "PSD-95 and Lin-7b interact with acid-sensing ion channel-3 and have opposite effects on H+- gated current."
      Hruska-Hageman A.M. , Benson C.J. , Leonard A.S. , Price M.P. , Welsh M.J.
      J. Biol. Chem.279:46962-46968(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ASIC3
    12. 12.
      "Angiomotin regulates endothelial cell-cell junctions and cell motility."
      Bratt A. , Birot O. , Sinha I. , Veitonmaeki N. , Aase K. , Ernkvist M. , Holmgren L.
      J. Biol. Chem.280:34859-34869(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH AMOT
    13. 13.
      "CIN85 is localized at synapses and forms a complex with S-SCAM via dendrin."
      Kawata A. , Iida J. , Ikeda M. , Sato Y. , Mori H. , Kansaku A. , Sumita K. , Fujiwara N. , Rokukawa C. , Hamano M. , Hirabayashi S. , Hata Y.
      J. Biochem.139:931-939(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DDN
    14. 14.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-730; SER-741 AND SER-1361;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    15. 15.
      "Solution structure of WW domains from the human membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1. MAGI-1."
      RIKEN structural genomics initiative (RSGI)
      Submitted (2008-04) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 295-401
    Product Feedback Wall
    Hot Genes
    Atf2 ASPRO ACE ALCAM C19orf80 Trap1a Gdf5
    Top Searches
    Ubiquitin-protein ligase metalloproteinase Ubiquitin ELISA Alpha Tumor necrosis Asprosin TRAP1A
    Why choose EIAAB
    Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more
    Further Information
    About us Protein center Bank account Distributors Terms & Conditions Career eiaab.com.cn

    Copyright & copy www.eiaab.com2006-2016 All Rights Reserved    EIAab         Email:eiaab@eiaab.com

    鄂ICP备10015095号-1

    鄂公网安备 42018502005535号

    Twitter