Protein name:
Myelin-associated glycoprotein ;
Alternative:
Siglec-4a ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Binds to RTN4R.
Function:
Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha-2,3-linked sialic acid. Isoform L-MAG is critical for the formation of myelin in the CNS, whereas isoform S-MAG is sufficient to maintain the integrity of myelin in PNS.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MIFLATLPLF | WIMISASRGG | HWGAWMPSTI | SAFEGTCVSI | PCRFDFPDEL |
100:
RPAVVHGVWY | FNSPYPKNYP | PVVFKSRTQV | VHESFQGRSR | LLGDLGLRNC |
150:
TLLLSTLSPE | LGGKYYFRGD | LGGYNQYTFS | EHSVLDIVNT | PNIVVPPEVV |
200:
AGTEVEVSCM | VPDNCPELRP | ELSWLGHEGL | GEPTVLGRLR | EDEGTWVQVS |
250:
LLHFVPTREA | NGHRLGCQAA | FPNTTLQFEG | YASLDVKYPP | VIVEMNSSVE |
300:
AIEGSHVSLL | CGADSNPPPL | LTWMRDGMVL | REAVAKSLYL | DLEEVTPGED |
350:
GVYACLAENA | YGQDNRTVEL | SVMYAPWKPT | VNGTVVAVEG | ETVSILCSTQ |
400:
SNPDPILTIF | KEKQILATVI | YESQLQLELP | AVTPEDDGEY | WCVAENQYGQ |
450:
RATAFNLSVE | FAPIILLESH | CAAARDTVQC | LCVVKSNPEP | SVAFELPSRN |
500:
VTVNETEREF | VYSERSGLLL | TSILTIRGQA | QAPPRVICTS | RNLYGTQSLE |
550:
LPFQGAHRLM | WAKIGPVGAV | VAFAILIAIV | CYITQTRRKK | NVTESSSFSG |
600:
GDNPHVLYSP | EFRISGAPDK | YESEKRLGSE | RRLLGLRGES | PELDLSYSHS |
626:
DLGKRPTKDS | YTLTEELAEY | AEIRVK
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Mouse Myelin-associated glycoprotein
ELISA Kit for Mouse Myelin-associated glycoprotein
ELISA Kit for Mouse Myelin-associated glycoprotein
CLIA Kit for Mouse Myelin-associated glycoprotein
CLIA Kit for Mouse Myelin-associated glycoprotein
CLIA Kit for Mouse Myelin-associated glycoprotein
Polyclonal Antibody for Mouse Myelin-associated glycoprotein
Polyclonal Antibody for Mouse Myelin-associated glycoprotein
Polyclonal Antibody for Mouse Myelin-associated glycoprotein
Monoclonal Antibody for Mouse Myelin-associated glycoprotein
Monoclonal Antibody for Mouse Myelin-associated glycoprotein
Monoclonal Antibody for Mouse Myelin-associated glycoprotein
Protein for Mouse Myelin-associated glycoprotein
Protein for Mouse Myelin-associated glycoprotein
Protein for Mouse Myelin-associated glycoprotein
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE (ISOFORMS L-MAG AND S-MAG)
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM S-MAG)
tissue :
Brain .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 78-88 AND 466-477;IDENTIFICATION BY MASS SPECTROMETRY
strain :
C57BL/6 .
tissue :
Brain .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
5.
"Sialoadhesin, myelin-associated glycoprotein and CD22 define a new family of sialic acid-dependent adhesion molecules of the immunoglobulin superfamily."
Kelm S.
,
Pelz A.
,
Schauer R.
,
Filbin M.T.
,
Tang S.
,
de Bellard M.E.
,
Schnaar R.L.
,
Mahoney J.A.
,
Hartnell A.
,
Bradfield P.
,
Crocker P.R.
Curr. Biol.4:965-972(1994)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SIALIC ACID-BINDING
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TISSUE SPECIFICITY
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH RTN4R