Map1s ELISA Kit for Mouse(Mus musculus) | EIAab.comMap1s ELISA Kit for Mouse(Mus musculus)

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Map1s (Gene name),

Microtubule-associated protein 1S (Protein name ), MAP1S_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Map1s(Bpy2ip1;Map8;Mtap1s);

Protein name:

Microtubule-associated protein 1S(MAP-1S);

Alternative:

Microtubule-associated protein 8;BPY2-interacting protein 1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Heterodimer of a heavy and a light chain. Interacts with microtubules and actin. Both MAP1S heavy and light chains interact with microtubules. MAP1S light chain interacts with actin. Interacts with ESR1, LRPPRC, RASSF1, microtubules and VCY2 (By similarity). Interacts (via C-terminus) with GAN (via Kelch domains).

Function:

Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule-organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis (By similarity). Involved in the formation of microtubule bundles.

Subcellular Location:

Nucleus Cytoplasm cytosol Cytoplasm cytoskeleton Cytoplasm cytoskeleton spindle Detected in perinuclear punctate network corresponding to mitochondrial aggregates and in the nucleus in cells exhibiting apoptosis. Associated specifically with microtubules stabilized by paclitaxel and colocalizes with RASSF1. In interphase cells, shows a diffuse cytoplasmic staining with partial localization to the microtubules. During the different stages of mitosis detected at the spindle microtubules. Detected in filopodia-like protrusions and synapses.

Protein Attributes:

Sequence length:

973

Sequence:

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