KIAA0430 ELISA Kit for Human(Homo sapiens) | EIAab.comKIAA0430 ELISA Kit for Human(Homo sapiens) | EIAab.com

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KIAA0430 (Gene name),

Meiosis arrest female protein 1 (Protein name ), MARF1_HUMAN from NCBI database.

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General Annotation

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Antigen Annotation

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3D

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Predicted Eptitope

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Vaild Sequence

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Related Databases

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Gene name:

KIAA0430(LKAP;MARF1);

Protein name:

Meiosis arrest female protein 1;

Alternative:

Limkain-b1;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with LIMK2.

Function:

Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks.

Subcellular Location:

Peroxisome

Protein Attributes:

Sequence length:

1742

Sequence:

50:

MMEGNGTENS | CSRTRGWLQQ | DNDAKPWLWK | FSNCFSRPEQ | TLPHSPQTKE |

100:

YMENKKVAVE | LKDVPSPLHA | GSKLFPAVPL | PDIRSLQQPK | IQLSSVPKVS |

150:

CCAHCPNEPS | TSPMRFGGGG | GGSGGTSSLI | HPGALLDSQS | TRTITCQVGS |

200:

GFAFQSASSL | QNASARNNLA | GIASDFPSMC | LESNLSSCKH | LPCCGKLHFQ |

250:

SCHGNVHKLH | QFPSLQGCTS | AGYFPCSDFT | SGAPGHLEEH | ISQSELTPHL |

300:

CTNSLHLNVV | PPVCLKGSLY | CEDCLNKPAR | NSIIDAAKVW | PNIPPPNTQP |

350:

APLAVPLCNG | CGTKGTGKET | TLLLATSLGK | AASKFGSPEV | AVAGQVLENL |

400:

PPIGVFWDIE | NCSVPSGRSA | TAVVQRIREK | FFKGHREAEF | ICVCDISKEN |

450:

KEVIQELNNC | QVTVAHINAT | AKNAADDKLR | QSLRRFANTH | TAPATVVLVS |

500:

TDVNFALELS | DLRHRHGFHI | ILVHKNQASE | ALLHHANELI | RFEEFISDLP |

550:

PRLPLKMPQC | HTLLYVYNLP | ANKDGKSVSN | RLRRLSDNCG | GKVLSITGCS |

600:

AILRFINQDS | AERAQKRMEN | EDVFGNRIIV | SFTPKNRELC | ETKSSNAIAD |

650:

KVKSPKKLKN | PKLCLIKDAS | EQSSSAKATP | GKGSQANSGS | ATKNTNVKSL |

700:

QELCRMESKT | GHRNSEHQQG | HLRLVVPTHG | NSSAAVSTPK | NSGVAEPVYK |

750:

TSQKKENLSA | RSVTSSPVEK | KDKEETVFQV | SYPSAFSKLV | ASRQVSPLLA |

800:

SQSWSSRSMS | PNLLNRASPL | AFNIANSSSE | ADCPDPFANG | ADVQVSNIDY |

850:

RLSRKELQQL | LQEAFARHGK | VKSVELSPHT | DYQLKAVVQM | ENLQDAIGAV |

900:

NSLHRYKIGS | KKILVSLATG | AASKSLSLLS | AETMSVLQDA | PACCLPLFKF |

950:

TDIYEKKFGH | KLNVSDLYKL | TDTVAIREQG | NGRLVCLLPS | SQARQSPLGS |

1000:

SQSHDGSSTN | CSPIIFEELE | YHEPVCRQHC | SNKDFSEHEF | DPDSYKIPFV |

1050:

ILSLKTFAPQ | VHSLLQTHEG | TVPLLSFPDC | YIAEFGDLEV | VQENQGGVPL |

1100:

EHFITCVPGV | NIATAQNGIK | VVKWIHNKPP | PPNTDPWLLR | SKSPVGNPQL |

1150:

IQFSREVIDL | LKSQPSCVIP | ISHFIPSYHH | HFAKQCRVSD | YGYSKLIELL |

1200:

EAVPHVLQIL | GMGSKRLLTL | THRAQVKRFT | QDLLKLLKSQ | ASKQVIVREF |

1250:

SQAYHWCFSK | DWDVTEYGVC | ELIDIVSEIP | DTTICLSQQD | NEMVICIPKR |

1300:

ERTQDEIERT | KQFSKDVVDL | LRHQPHFRMP | FNKFIPSYHH | HFGRQCKLAY |

1350:

YGFTKLLELF | EAIPDTLQVL | ECGEEKILTL | TEVERFKALA | AQFVKLLRSQ |

1400:

KDNCLMMTDL | LTEYAKTFGY | TFRLQDYDVS | SISALTQKLC | HVVKVADIES |

1450:

GRQIQLINRK | SLRSLTAQLL | VLLMSWEGTT | HLSVEELKRH | YESTHNTPLN |

1500:

PCEYGFMTLT | ELLKSLPYLV | EVFTNDKMEE | CVKLTSLYLF | AKNVRSLLHT |

1550:

YHYQQIFLHE | FSMAYTKYVG | ETLQPKTYGH | SSVEELLGAI | PQVVWIKGHG |

1600:

HKRIVVLKND | MKSRLSSLSL | SPANHENQPS | EGERILEVPE | SHTASELKLG |

1650:

ADGSGPSHTE | QELLRLTDDS | PVDLLCAPVP | SCLPSPQLRP | DPVILQSADL |

1700:

IQFEERPQEP | SEIMILNQEE | KMEIPIPGKS | KTLTSDSSSS | CISAAVPVPP |

1742:

CPSSETSESL | LSKDPVESPA | KKQPKNRVKL | AANFSLAPIT | KL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

MIM:

KEGG:

UniGene:

Pfam:

Uniprot:

FOR

ELISA Kit for Human Meiosis arrest female protein 1

CLIA Kit for Human Meiosis arrest female protein 1

Polyclonal Antibody for Human Meiosis arrest female protein 1

Monoclonal Antibody for Human Meiosis arrest female protein 1

Protein for Human Meiosis arrest female protein 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

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Recovery

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Linearity

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

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References

1.

"Limkain b1, a novel human autoantigen localized to a subset of ABCD3 and PXF marked peroxisomes."
Dunster K. , Lai F.P.L. , Sentry J.W.
Clin. Exp. Immunol.140:556-563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);SUBCELLULAR LOCATION
2.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5)
tissue: Testis.
3.

"Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q."
Loftus B.J. , Kim U.-J. , Sneddon V.P. , Kalush F. , Brandon R. , Fuhrmann J. , Mason T. , Crosby M.L. , Barnstead M. , Cronin L. , Mays A.D. , Cao Y. , Xu R.X. , Kang H.-L. , Mitchell S. , Eichler E.E. , Harris P.C. , Venter J.C. , more...
Genomics60:295-308(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"The sequence and analysis of duplication-rich human chromosome 16."
Martin J. , Han C. , Gordon L.A. , Terry A. , Prabhakar S. , She X. , Xie G. , Hellsten U. , Chan Y.M. , Altherr M. , Couronne O. , Aerts A. , Bajorek E. , Black S. , Blumer H. , Branscomb E. , Brown N.C. , Bruno W.J. , more...
Nature432:988-994(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 3 AND 4)
tissue: Brain.
tissue: Testis.
7.

"Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro."
Ishikawa K. , Nagase T. , Nakajima D. , Seki N. , Ohira M. , Miyajima N. , Tanaka A. , Kotani H. , Nomura N. , Ohara O.
DNA Res.4:307-313(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 237-1742 (ISOFORM 1)
tissue: Brain.
8.

Ohara O. , Nagase T. , Kikuno R.
Submitted (2005-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
9.

"Molecular cloning and characterization of novel large protein, limkain b1, which associates with the LIM-kinase 2."
Miyamoto K. , Nakamura T. , Shirakawa K. , Matsumoto K.
Submitted (1998-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 312-615 (ISOFORM 1);INTERACTION WITH LIMK2
10.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
11.

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1091;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Leukemic T-cell.
12.

"LOTUS, a new domain associated with small RNA pathways in the germline."
Callebaut I. , Mornon J.P.
Bioinformatics26:1140-1144(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION OF THE HTH OST-TYPE DOMAIN
13.

"OST-HTH: a novel predicted RNA-binding domain."
Anantharaman V. , Zhang D. , Aravind L.
Biol. Direct5:13-13(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION OF THE HTH OST-TYPE DOMAIN
14.

"Solution structure of the RNA recognition motif in KIAA0430 protein."
RIKEN structural genomics initiative (RSGI)
Submitted (2006-09) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 789-875

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