Gene name:
MARCH2 (HSPC240;RNF172) ;
Protein name:
E3 ubiquitin-protein ligase MARCH2 ;
Alternative:
Membrane-associated RING-CH protein II (MARCH-II) ;Membrane-associated RING finger protein 2 ;RING finger protein 172 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with STX6 (By similarity). Interacts with MARCH3.
Function:
E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May be involved in endosomal trafficking through interaction with STX6.
Subcellular Location:
Endoplasmic reticulum membrane
Multi-pass membrane protein
Lysosome membrane
Multi-pass membrane protein
Endosome membrane
Multi-pass membrane protein
Protein Attributes:
50:
MTTGDCCHLP | GSLCDCSGSP | AFSKVVEATG | LGPPQYVAQV | TSRDGRLLST |
100:
VIRALDTPSD | GPFCRICHEG | ANGECLLSPC | GCTGTLGAVH | KSCLEKWLSS |
150:
SNTSYCELCH | TEFAVEKRPR | PLTEWLKDPG | PRTEKRTLCC | DMVCFLFITP |
200:
LAAISGWLCL | RGAQDHLRLH | SQLEAVGLIA | LTIALFTIYV | LWTLVSFRYH |
246:
CQLYSEWRKT | NQKVRLKIRE | ADSPEGPQHS | PLAAGLLKKV | AEETPV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Rat
Mouse
Human
ELISA Kit for Human E3 ubiquitin-protein ligase MARCH2
ELISA Kit for Human E3 ubiquitin-protein ligase MARCH2
ELISA Kit for Human E3 ubiquitin-protein ligase MARCH2
ELISA Kit for Human E3 ubiquitin-protein ligase MARCH2
CLIA Kit for Human E3 ubiquitin-protein ligase MARCH2
CLIA Kit for Human E3 ubiquitin-protein ligase MARCH2
CLIA Kit for Human E3 ubiquitin-protein ligase MARCH2
CLIA Kit for Human E3 ubiquitin-protein ligase MARCH2
Polyclonal Antibody for Human E3 ubiquitin-protein ligase MARCH2
Polyclonal Antibody for Human E3 ubiquitin-protein ligase MARCH2
Polyclonal Antibody for Human E3 ubiquitin-protein ligase MARCH2
Polyclonal Antibody for Human E3 ubiquitin-protein ligase MARCH2
Monoclonal Antibody for Human E3 ubiquitin-protein ligase MARCH2
Monoclonal Antibody for Human E3 ubiquitin-protein ligase MARCH2
Monoclonal Antibody for Human E3 ubiquitin-protein ligase MARCH2
Monoclonal Antibody for Human E3 ubiquitin-protein ligase MARCH2
Protein for Human E3 ubiquitin-protein ligase MARCH2
Protein for Human E3 ubiquitin-protein ligase MARCH2
Protein for Human E3 ubiquitin-protein ligase MARCH2
Protein for Human E3 ubiquitin-protein ligase MARCH2
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION
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Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Umbilical cord blood .
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Europe PMC ]
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Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT THR-54
tissue :
Brain .
tissue :
Skin .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH MARCH3