Gene name:
MARCH4 (KIAA1399;RNF174) ;
Protein name:
E3 ubiquitin-protein ligase MARCH4 ;
Alternative:
Membrane-associated RING-CH protein IV (MARCH-IV) ;Membrane-associated RING finger protein 4 ;RING finger protein 174 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Subcellular Location:
Golgi apparatus membrane
Multi-pass membrane protein
Protein Attributes:
50:
MLMPLCGLLW | WWWCCCSGWY | CYGLCAPAPQ | MLRHQGLLKC | RCRMLFNDLK |
100:
VFLLRRPPQA | PLPMHGDPQP | PGLAANNTLP | ALGAGGWAGW | RGPREVVGRE |
150:
PPPVPPPPPL | PPSSVEDDWG | GPATEPPASL | LSSASSDDFC | KEKTEDRYSL |
200:
GSSLDSGMRT | PLCRICFQGP | EQGELLSPCR | CDGSVKCTHQ | PCLIKWISER |
250:
GCWSCELCYY | KYHVIAISTK | NPLQWQAISL | TVIEKVQVAA | AILGSLFLIA |
300:
SISWLIWSTF | SPSARWQRQD | LLFQICYGMY | GFMDVVCIGL | IIHEGPSVYR |
350:
IFKRWQAVNQ | QWKVLNYDKT | KDLEDQKAGG | RTNPRTSSST | QANIPSSEEE |
400:
TAGTPAPEQG | PAQAAGHPSG | PLSHHHCAYT | ILHILSHLRP | HEQRSPPGSS |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human E3 ubiquitin-protein ligase MARCH4
ELISA Kit for Human E3 ubiquitin-protein ligase MARCH4
CLIA Kit for Human E3 ubiquitin-protein ligase MARCH4
CLIA Kit for Human E3 ubiquitin-protein ligase MARCH4
Polyclonal Antibody for Human E3 ubiquitin-protein ligase MARCH4
Polyclonal Antibody for Human E3 ubiquitin-protein ligase MARCH4
Monoclonal Antibody for Human E3 ubiquitin-protein ligase MARCH4
Monoclonal Antibody for Human E3 ubiquitin-protein ligase MARCH4
Protein for Human E3 ubiquitin-protein ligase MARCH4
Protein for Human E3 ubiquitin-protein ligase MARCH4
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Liver .
tissue :
Pancreas .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION