Mybbp1a ELISA Kit for Mouse(Mus musculus) | EIAab.comMybbp1a ELISA Kit for Mouse(Mus musculus)

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Mybbp1a (Gene name),

Myb-binding protein 1A (Protein name ), MBB1A_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Mybbp1a(P160);

Protein name:

Myb-binding protein 1A;

Alternative:

Myb-binding protein of 160 kDa;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Component of the B-WICH complex, at least composed of SMARCA5/SNF2H, BAZ1B/WSTF, SF3B1, DEK, MYO1C, ERCC6, MYBBP1A and DDX21 (By similarity). Binds to and represses JUN and MYB via the leucine zipper regions present in these proteins. Also binds to and represses PPARGC1A: this interaction is abrogated when PPARGC1A is phosphorylated by MAPK1/ERK. Binds to and stimulates transcription by AHR. Binds to KPNA2.

Function:

May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity).

Subcellular Location:

Nucleus nucleolus Cytoplasm Predominantly nucleolar. Also shuttles between the nucleus and cytoplasm. Nuclear import may be mediated by KPNA2, while export appears to depend partially on XPO1/CRM1.

Protein Attributes:

Sequence length:

1344

Sequence:

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1150:

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1250:

1300:

1344:

RKSPHPQSAL | PKKRARLSLV | SRSPSLLQSG | VKKRRVASRR | VQTP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.147946

String:

Q7TPV4

Pfam:

PF04931

KEGG:

mmu:18432

Uniprot:

Q7TPV4

FOR

ELISA Kit for Mouse Myb-binding protein 1A

CLIA Kit for Mouse Myb-binding protein 1A

Polyclonal Antibody for Mouse Myb-binding protein 1A

Monoclonal Antibody for Mouse Myb-binding protein 1A

Protein for Mouse Myb-binding protein 1A

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning reveals that the p160 Myb-binding protein is a novel, predominantly nucleolar protein which may play a role in transactivation by Myb."
Tavner F.J. , Simpson R. , Tashiro S. , Favier D. , Jenkins N.A. , Gilbert D.J. , Copeland N.G. , Macmillan E.M. , Lutwyche J. , Keough R.A. , Ishii S. , Gonda T.J.
Mol. Cell. Biol.18:989-1002(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 43-53; 205-211; 286-290; 458-465 AND 488-496;INTERACTION WITH JUN AND MYB;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
2.

"Structural organization of the murine myb-binding protein p160 (Mybbp1a) gene."
Keough R.A. , Gonda T.J.
Submitted (2001-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C3H/He.
tissue: Eye.
tissue: Mammary gland.
tissue: Osteoblast.
5.

"Myb-binding protein 1a augments AhR-dependent gene expression."
Jones L.C. , Okino S.T. , Gonda T.J. , Whitlock J.P. Jr.
J. Biol. Chem.277:22515-22519(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE;FUNCTION;INTERACTION WITH AHR
6.

"Myb-binding protein 1a is a nucleocytoplasmic shuttling protein that utilizes CRM1-dependent and independent nuclear export pathways."
Keough R.A. , Macmillan E.M. , Lutwyche J.K. , Gardner J.M. , Tavner F.J. , Jans D.A. , Henderson B.R. , Gonda T.J.
Exp. Cell Res.289:108-123(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH KPNA2;MUTAGENESIS OF LEU-249; VAL-251; LEU-272 AND LEU-274;DOMAINS NES AND NLS
7.

"Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK."
Fan M. , Rhee J. , St Pierre J. , Handschin C. , Puigserver P. , Lin J. , Jaeger S. , Erdjument-Bromage H. , Tempst P. , Spiegelman B.M.
Genes Dev.18:278-289(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION BY MASS SPECTROMETRY;INTERACTION WITH PPARGC1A
8.

"Phosphoproteomic analysis of the developing mouse brain."
Ballif B.A. , Villen J. , Beausoleil S.A. , Schwartz D. , Gygi S.P.
Mol. Cell. Proteomics3:1093-1101(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic brain.
9.

"Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
Trinidad J.C. , Specht C.G. , Thalhammer A. , Schoepfer R. , Burlingame A.L.
Mol. Cell. Proteomics5:914-922(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Brain.
10.

"Large-scale phosphorylation analysis of mouse liver."
Villen J. , Beausoleil S.A. , Gerber S.A. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-1277 AND SER-1280;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.
11.

"The phagosomal proteome in interferon-gamma-activated macrophages."
Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1253 AND SER-1280;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
12.

"Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
Sweet S.M. , Bailey C.M. , Cunningham D.L. , Heath J.K. , Cooper H.J.
Mol. Cell. Proteomics8:904-912(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1253;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
tissue: Embryonic fibroblast.
13.

"Molecular characterization of Mybbp1a as a co-repressor on the Period2 promoter."
Hara Y. , Onishi Y. , Oishi K. , Miyazaki K. , Fukamizu A. , Ishida N.
Nucleic Acids Res.37:1115-1126(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH CLOCK AND CRY1
14.

"Citrullination regulates pluripotency and histone H1 binding to chromatin."
Christophorou M.A. , Castelo-Branco G. , Halley-Stott R.P. , Oliveira C.S. , Loos R. , Radzisheuskaya A. , Mowen K.A. , Bertone P. , Silva J.C. , Zernicka-Goetz M. , Nielsen M.L. , Gurdon J.B. , Kouzarides T.
Nature507:104-108(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CITRULLINATION AT ARG-1322

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