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Index > Protein center > MC3R(Gene name) > Human
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  • MC3R (Gene name),
  • Melanocortin receptor 3 (Protein name ),  MC3R_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    MC3R;
    Protein name:
    Melanocortin receptor 3(MC3-R);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    360
    Sequence:
    50:
    MSIQKTYLEG | DFVFPVSSSS | FLRTLLEPQL | GSALLTAMNA | SCCLPSVQPT | 
    100:
    LPNGSEHLQA | PFFSNQSSSA | FCEQVFIKPE | VFLSLGIVSL | LENILVILAV | 
    150:
    VRNGNLHSPM | YFFLCSLAVA | DMLVSVSNAL | ETIMIAIVHS | DYLTFEDQFI | 
    200:
    QHMDNIFDSM | ICISLVASIC | NLLAIAVDRY | VTIFYALRYH | SIMTVRKALT | 
    250:
    LIVAIWVCCG | VCGVVFIVYS | ESKMVIVCLI | TMFFAMMLLM | GTLYVHMFLF | 
    300:
    ARLHVKRIAA | LPPADGVAPQ | QHSCMKGAVT | ITILLGVFIF | CWAPFFLHLV | 
    350:
    LIITCPTNPY | CICYTAHFNT | YLVLIMCNSV | IDPLIYAFRS | LELRNTFREI | 
    360:
    LCGCNGMNLG | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    Pfam:
    KEGG:
    MIM:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human MC3-R
    ELISA Kit for Human MC3-R
    ELISA Kit for Human MC3-R
    CLIA Kit for Human MC3-R
    CLIA Kit for Human MC3-R
    CLIA Kit for Human MC3-R
    Polyclonal Antibody for Human MC3-R
    Polyclonal Antibody for Human MC3-R
    Polyclonal Antibody for Human MC3-R
    Monoclonal Antibody for Human MC3-R
    Monoclonal Antibody for Human MC3-R
    Monoclonal Antibody for Human MC3-R
    Protein for Human MC3-R
    Protein for Human MC3-R
    Protein for Human MC3-R

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ILE-44
    2. 2.
      "cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
      Kopatz S.A. , Aronstam R.S. , Sharma S.V.
      Submitted (2003-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    3. 3.
      "The DNA sequence and comparative analysis of human chromosome 20."
      Deloukas P. , Matthews L.H. , Ashurst J.L. , Burton J. , Gilbert J.G.R. , Jones M. , Stavrides G. , Almeida J.P. , Babbage A.K. , Bagguley C.L. , Bailey J. , Barlow K.F. , Bates K.N. , Beard L.M. , Beare D.M. , Beasley O.P. , Bird C.P. , Blakey S.E. , more...
      Nature414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    5. 5.
      "Identification of the translation start site of the human melanocortin 3 receptor."
      Tarnow P. , Rediger A. , Schulz A. , Gruters A. , Biebermann H.
      Obes. Facts5:45-51(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TRANSLATIONAL START SITE
    6. 6.
      "A novel melanocortin 3 receptor gene (MC3R) mutation associated with severe obesity."
      Lee Y.-S. , Poh L.K.-S. , Loke K.-Y.
      J. Clin. Endocrinol. Metab.87:1423-1426(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ASN-146;ASSOCIATION WITH SUSCEPTIBILITY TO OBESITY
    7. 7.
      "Functional characterization of melanocortin-3 receptor variants identify a loss-of-function mutation involving an amino acid critical for G protein-coupled receptor activation."
      Tao Y.-X. , Segaloff D.L.
      J. Clin. Endocrinol. Metab.89:3936-3942(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF VARIANTS ILE-44 AND ASN-146
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT SER-298;CHARACTERIZATION OF VARIANT SER-298;ASSOCIATION WITH SUSCEPTIBILITY TO OBESITY
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