Mcm2 ELISA Kit for Mouse(Mus musculus) | EIAab.comMcm2 ELISA Kit for Mouse(Mus musculus)

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Mcm2 (Gene name),

DNA replication licensing factor MCM2 (Protein name ), MCM2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Mcm2(Bm28;Cdcl1;Kiaa0030;Mcmd2);

Protein name:

DNA replication licensing factor MCM2;

Alternative:

Nuclear protein BM28;Minichromosome maintenance protein 2 homolog;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Component of the MCM2-7 complex. The complex forms a toroidal hexameric ring with the proposed subunit order MCM2-MCM6-MCM4-MCM7-MCM3-MCM5. Interacts with KAT7 and DBF4. May interact with MCM10.

Function:

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

904

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

904:

LQQF

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P97310

SMR:

P97310

Pfam:

PF00493

KEGG:

mmu:17216

UniGene:

Mm.16711

Uniprot:

P97310

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ELISA Kit for Mouse DNA replication licensing factor MCM2

Cat.:

E1768h

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Packing:

96T

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ELISA Kit for Mouse DNA replication licensing factor MCM2

Cat.:

E1768m

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MSDS:

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Packing:

96T

CLIA Kit for Mouse DNA replication licensing factor MCM2

Cat.:

U1768h

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Manual:

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MSDS:

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Packing:

96T

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CLIA Kit for Mouse DNA replication licensing factor MCM2

Cat.:

U1768m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse DNA replication licensing factor MCM2

Cat.:

P1768Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse DNA replication licensing factor MCM2

Cat.:

P1768Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse DNA replication licensing factor MCM2

Protein for Mouse DNA replication licensing factor MCM2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Mouse MCM proteins: complex formation and transportation to the nucleus."
Kimura H. , Ohtomo T. , Yamaguchi M. , Ishii A. , Sugimoto K.
Genes Cells1:977-993(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 217-224; 376-384 AND 477-487
2.

Kimura H.
Submitted (1997-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
3.

"Clone 10d/BM28 (CDCL1), an early S-phase protein, is an important growth regulator of melanoma."
Spanjaard R.A. , Lee P.J. , Sarkar S. , Goedegebuure P.S. , Eberlein T.J.
Cancer Res.57:5122-5128(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Melanoma.
4.

"Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Koseki H. , Hiraoka S. , Saga Y. , Nagase T. , Ohara O. , Koga H.
DNA Res.10:167-180(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Embryonic tail.
5.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: NOD.
tissue: Thymus.
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6.
tissue: Brain.
7.

"Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis."
Chu C.C. , Paul W.E.
Mol. Immunol.35:487-502(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 477-668
strain: BALB/c.
tissue: Spleen.
8.

"Identification, characterization and chromosomal localization of the cognate human and murine DBF4 genes."
Lepke M. , Puetter V. , Staib C. , Kneissl M. , Berger C. , Hoehn K. , Nanda I. , Schmid M. , Grummt F.
Mol. Gen. Genet.262:220-229(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DBF4
strain: C57BL/6J.
tissue: Egg.
tissue: Embryo.
9.

"Replication factors MCM2 and ORC1 interact with the histone acetyltransferase HBO1."
Burke T.W. , Cook J.G. , Asano M. , Nevins J.R.
J. Biol. Chem.276:15397-15408(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH KAT7;MUTAGENESIS OF LEU-237
10.

"Phosphoproteomic analysis of the developing mouse brain."
Ballif B.A. , Villen J. , Beausoleil S.A. , Schwartz D. , Gygi S.P.
Mol. Cell. Proteomics3:1093-1101(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic brain.
11.

"A differential phosphoproteomic analysis of retinoic acid-treated P19 cells."
Smith J.C. , Duchesne M.A. , Tozzi P. , Ethier M. , Figeys D.
J. Proteome Res.6:3174-3186(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Teratocarcinoma.
12.

"Large-scale phosphorylation analysis of mouse liver."
Villen J. , Beausoleil S.A. , Gerber S.A. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.104:1488-1493(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21; SER-27; SER-139 AND SER-140;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Liver.
13.

"Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
Sweet S.M. , Bailey C.M. , Cunningham D.L. , Heath J.K. , Cooper H.J.
Mol. Cell. Proteomics8:904-912(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-12; SER-21; SER-27; SER-139 AND SER-140;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
tissue: Embryonic fibroblast.

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