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Index > Protein center > Mcm8(Gene name) > Mouse
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  • Mcm8 (Gene name),
  • DNA replication licensing factor MCM8 (Protein name ),  MCM8_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Mcm8;
    Protein name:
    DNA replication licensing factor MCM8;
    Alternative:
    Minichromosome maintenance 8;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with CDC6 and ORC2.
    Function:
    May have a role in the control of cell proliferation. Appears to be involved in the activation of the prereplicative complex (pre-RC) during G(1) phase by recruiting CDC6 to the origin recognition complex (ORC). Binds chromatin throughout the cell cycle.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    833
    Sequence:
    50:
    MSGAYRGRGF | GRGRFQSWKR | GRGGGNFSGR | WRERENRVDL | NEASGKHASA | 
    100:
    QASQPLLQQS | TLDQFIPYKG | WKLYFSEVYS | NNSPFIEKIQ | AFEKFFTRHI | 
    150:
    DLYDKDEIER | KGSILVDFKE | LTKADEITNL | IPDIENALRD | APEKTLACMG | 
    200:
    LAIHQVLTKD | LERHAAELQA | QEGLSNGGET | MVNVPHIYAR | VYNYEPLTHL | 
    250:
    KNIRATCYGK | YISIRGTVVR | VSNIKPLCTN | MAFQCAACGE | IQSFPLPDGK | 
    300:
    YTLPTKCPVP | ACRGRSFAPL | RSSPLTVTLD | WQLIKIQELM | SDAQREAGRI | 
    350:
    PRTIECELVH | DLVDSCVPGD | TVTVTGIVKV | SNSEEGSRNK | NDKCMFLLYI | 
    400:
    EANSVSNSKG | PKAQTAEDGC | KHGTLMEFSL | KDLYAIREIQ | AEENLLKLVV | 
    450:
    NSLCPVIFGH | ELVKAGLTLA | LFGGSQKYAD | DKNRIPIRGD | PHVLIVGDPG | 
    500:
    LGKSQMLQAA | CNVAPRGVYV | CGNTTTSSGL | TVTLSKDSSS | GDFALEAGAL | 
    550:
    VLGDQGICGI | DEFDKMGNQH | QALLEAMEQQ | SISLAKAGVV | CSLPARTSII | 
    600:
    AAANPVGGHY | NKARTVSENL | KMGSALLSRF | DLVFILLDTP | NEQHDHLLSE | 
    650:
    HVIAIRAGKQ | KAVSSATVTR | VLSQDSNTSV | LEVVSEKPLS | ERLKVAPGEQ | 
    700:
    TDPIPHQLLR | KYIGYARQYV | HPRLSTDAAQ | ALQDFYLELR | KQSQRVGSSP | 
    750:
    ITTRQLESLI | RLTEARARLE | LREEATREDA | EDIIEIMKHS | MLGTYSDEFG | 
    800:
    NLDFERSQHG | SGMSNRSTAK | RFISALNSIA | ERTYNNIFQY | HQLRQIAKEL | 
    833:
    NIQVADFENF | IGSLNDQGYL | LKKGPKIYQL | QTM
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    String:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse DNA replication licensing factor MCM8
    ELISA Kit for Mouse DNA replication licensing factor MCM8
    ELISA Kit for Mouse DNA replication licensing factor MCM8
    ELISA Kit for Mouse DNA replication licensing factor MCM8
    ELISA Kit for Mouse DNA replication licensing factor MCM8
    CLIA Kit for Mouse DNA replication licensing factor MCM8
    CLIA Kit for Mouse DNA replication licensing factor MCM8
    CLIA Kit for Mouse DNA replication licensing factor MCM8
    CLIA Kit for Mouse DNA replication licensing factor MCM8
    CLIA Kit for Mouse DNA replication licensing factor MCM8
    Polyclonal Antibody for Mouse DNA replication licensing factor MCM8
    Polyclonal Antibody for Mouse DNA replication licensing factor MCM8
    Polyclonal Antibody for Mouse DNA replication licensing factor MCM8
    Polyclonal Antibody for Mouse DNA replication licensing factor MCM8
    Polyclonal Antibody for Mouse DNA replication licensing factor MCM8
    Monoclonal Antibody for Mouse DNA replication licensing factor MCM8
    Monoclonal Antibody for Mouse DNA replication licensing factor MCM8
    Monoclonal Antibody for Mouse DNA replication licensing factor MCM8
    Monoclonal Antibody for Mouse DNA replication licensing factor MCM8
    Monoclonal Antibody for Mouse DNA replication licensing factor MCM8
    Protein for Mouse DNA replication licensing factor MCM8
    Protein for Mouse DNA replication licensing factor MCM8
    Protein for Mouse DNA replication licensing factor MCM8
    Protein for Mouse DNA replication licensing factor MCM8
    Protein for Mouse DNA replication licensing factor MCM8

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    Linearity
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6J.
      tissue: Embryonic stem cell.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      strain: C57BL/6.
      tissue: Fetal brain.
    5. 5.
      "MCM8- and MCM9-deficient mice reveal gametogenesis defects and genome instability due to impaired homologous recombination."
      Lutzmann M. , Grey C. , Traver S. , Ganier O. , Maya-Mendoza A. , Ranisavljevic N. , Bernex F. , Nishiyama A. , Montel N. , Gavois E. , Forichon L. , de Massy B. , Mechali M.
      Mol. Cell47:523-534(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION IN THE MCM8-MCM9 COMPLEX;DISRUPTION PHENOTYPE
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