Abcb4 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comAbcb4 ELISA Kit for Rat(Rattus norvegicus)

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Abcb4 (Gene name),

Multidrug resistance protein 3 (Protein name ), MDR3_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Abcb4(Mdr2;Pgp3;Pgy2);

Protein name:

Multidrug resistance protein 3;

Alternative:

Multidrug resistance protein 2;ATP-binding cassette sub-family B member 4;P-glycoprotein 3;P-glycoprotein 2;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with HAX1.

Function:

Mediates ATP-dependent export of organic anions and drugs from the cytoplasm. Hydrolyzes ATP with low efficiency. Not capable of conferring drug resistance. Mediates the translocation of phosphatidylcholine across the canalicular membrane of the hepatocyte.

Subcellular Location:

Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

1278

Sequence:

50:

100:

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1150:

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1250:

1278:

EHGTHQQLLA | QKGIYFSMVN | IQAGTQNL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.82691

Pfam:

PF00664

KEGG:

rno:24891

Uniprot:

Q08201

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ELISA Kit for Rat Multidrug resistance protein 3

Cat.:

E10409h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Rat Multidrug resistance protein 3

Cat.:

E10409m

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Rat Multidrug resistance protein 3

Cat.:

E10409r

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat Multidrug resistance protein 3

Cat.:

U10409m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat Multidrug resistance protein 3

Cat.:

U10409h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat Multidrug resistance protein 3

Cat.:

U10409r

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat Multidrug resistance protein 3

Cat.:

P10409Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Multidrug resistance protein 3

Monoclonal Antibody for Rat Multidrug resistance protein 3

Protein for Rat Multidrug resistance protein 3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤4.9%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤8.7%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

Recovery was determined by spiking various levels of ABCB4 into serum and plasma .

Sample Type	Average(%)	Recovery Range(%)
Serum	100	97-108
Plasma	99	95-106

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ABCB4 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	94-105%	95-103%	96-105%	92-109%
EDTA plasma(n=5)	93-105%	92-107%	95-103%	93-106%
heparin plasma(n=5)	94-104%	91-105%	92-108%	91-109%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning and regulation of the rat mdr2 gene."
Brown P.C. , Thorgeirsson S.S. , Silverman J.A.
Nucleic Acids Res.21:3885-3891(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: Fischer.
2.

"Identification of distinct P-glycoprotein gene sequences in rat."
Deuchars K.L. , Duthie M. , Ling V.
Biochim. Biophys. Acta1130:157-165(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1211-1278
strain: Sprague-Dawley.
tissue: Liver.
3.

"Identification of HAX-1 as a protein that binds bile salt export protein and regulates its abundance in the apical membrane of Madin-Darby canine kidney cells."
Ortiz D.F. , Moseley J. , Calderon G. , Swift A.L. , Li S. , Arias I.M.
J. Biol. Chem.279:32761-32770(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HAX1

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