Protein name:
Methyl-CpG-binding protein 2 (MeCp-2 protein;MeCp2) ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with CDKL5 (By similarity). Interacts with FNBP3.
Function:
Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A.
Subcellular Location:
Nucleus
Colocalized with methyl-CpG in the genome.
Protein Attributes:
50:
MVAGMLGLRE | EKSEDQDLQG | LRDKPLKFKK | AKKDKKEDKE | GKHEPLQPSA |
100:
HHSAEPAEAG | KAETSESSGS | APAVPEASAS | PKQRRSIIRD | RGPMYDDPTL |
150:
PEGWTRKLKQ | RKSGRSAGKY | DVYLINPQGK | AFRSKVELIA | YFEKVGDTSL |
200:
DPNDFDFTVT | GRGSPSRREQ | KPPKKPKSPK | APGTGRGRGR | PKGSGTGRPK |
250:
AAASEGVQVK | RVLEKSPGKL | VVKMPFQASP | GGKGEGGGAT | TSAQVMVIKR |
300:
PGRKRKAEAD | PQAIPKKRGR | KPGSVVAAAA | AEAKKKAVKE | SSIRSVHETV |
350:
LPIKKRKTRE | TVSIEVKEVV | KPLLVSTLGE | KSGKGLKTCK | SPGRKSKESS |
400:
PKGRSSSASS | PPKKEHHHHH | HHSESTKAPM | PLLPSPPPPE | PESSEDPISP |
450:
PEPQDLSSSI | CKEEKMPRGG | SLESDGCPKE | PAKTQPMVAT | TTTVAEKYKH |
484:
RGEGERKDIV | SSSMPRPNRE | EPVDSRTPVT | ERVS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Mouse
ELISA Kit for Mouse MeCp-2 protein
ELISA Kit for Mouse MeCp-2 protein
ELISA Kit for Mouse MeCp-2 protein
CLIA Kit for Mouse MeCp-2 protein
CLIA Kit for Mouse MeCp-2 protein
CLIA Kit for Mouse MeCp-2 protein
Polyclonal Antibody for Mouse MeCp-2 protein
Polyclonal Antibody for Mouse MeCp-2 protein
Polyclonal Antibody for Mouse MeCp-2 protein
Monoclonal Antibody for Mouse MeCp-2 protein
Monoclonal Antibody for Mouse MeCp-2 protein
Monoclonal Antibody for Mouse MeCp-2 protein
Protein for Mouse MeCp-2 protein
Protein for Mouse MeCp-2 protein
Protein for Mouse MeCp-2 protein
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE (ISOFORM A)
strain :
C57BL/6 .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE (ISOFORM A)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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C57BL/6J .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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FVB/N .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-321 AND LYS-447;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Embryonic fibroblast .