Mecp2 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comMecp2 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Mecp2(Gene name) > Rat

Mecp2 (Gene name),

Methyl-CpG-binding protein 2 (Protein name ), MECP2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Mecp2;

Protein name:

Methyl-CpG-binding protein 2(MeCp-2 protein;MeCp2);

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with FNBP3 (By similarity). Interacts with CDKL5.

Function:

Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A.

Subcellular Location:

Nucleus Colocalized with methyl-CpG in the genome.

Protein Attributes:

Sequence length:

492

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

492:

TVAEKYKHRG | EGERKDIVSS | SMPRPNREEP | VDSRTPVTER | VS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF01429

KEGG:

rno:29386

String:

Q00566

UniGene:

Rn.38416

UniGene:

Rn.9680

SMR:

Q00566

Uniprot:

Q00566

FOR

ELISA Kit for Rat MeCp-2 protein

Cat.:

E15238r

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Rat MeCp-2 protein

Cat.:

E15238h

Price:

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MSDS:

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Packing:

96T

ELISA Kit for Rat MeCp-2 protein

Cat.:

E15238m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat MeCp-2 protein

Cat.:

U15238r

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat MeCp-2 protein

Cat.:

U15238h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat MeCp-2 protein

Cat.:

U15238m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat MeCp-2 protein

Cat.:

P15238Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat MeCp-2 protein

Cat.:

P15238Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat MeCp-2 protein

Cat.:

P15238Rb-r

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat MeCp-2 protein

Protein for Rat MeCp-2 protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA."
Lewis J.D. , Meehan R.R. , Henzel W.J. , Maurer-Fogy I. , Jeppesen P. , Klein F. , Bird A.
Cell69:905-914(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A);PARTIAL PROTEIN SEQUENCE
strain: Wistar.
tissue: Brain.
tissue: Corpus striatum.
2.

"Fluoxetine and cocaine induce the epigenetic factors MeCP2 and MBD1 in adult rat brain."
Cassel S. , Carouge D. , Gensburger C. , Anglard P. , Burgun C. , Dietrich J.-B. , Aunis D. , Zwiller J.
Mol. Pharmacol.70:487-492(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS A AND B);SUBCELLULAR LOCATION;INDUCTION BY FLUOXETINE AND COCAINE
strain: Wistar.
tissue: Brain cortex.
3.

"Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation."
Zhou Z. , Hong E.J. , Cohen S. , Zhao W.-N. , Ho H.H. , Schmidt L. , Chen W.G. , Lin Y. , Savner E. , Griffith E.C. , Hu L. , Steen J.A.J. , Weitz C.J. , Greenberg M.E.
Neuron52:255-269(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-80; SER-229 AND SER-421;IDENTIFICATION BY MASS SPECTROMETRY
4.

"Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation."
Nan X. , Hou J. , Maclean A. , Nasir J. , Lafuente M.J. , Shu X. , Kriaucionis S. , Bird A.
Proc. Natl. Acad. Sci. U.S.A.104:2709-2714(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ATRX

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