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Index > Protein center > Med13(Gene name) > Mouse
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  • Med13 (Gene name),
  • Mediator of RNA polymerase II transcription subunit 13 (Protein name ),  MED13_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Med13(Kiaa0593;Thrap1;Trap240);
    Protein name:
    Mediator of RNA polymerase II transcription subunit 13;
    Alternative:
    Thyroid hormone receptor-associated protein complex 240 kDa component(Trap240);Thyroid hormone receptor-associated protein 1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
    Function:
    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    2171
    Sequence:
    50:
    MSSSFVSNGA | SLEDCHCNLF | CLADLTGIKW | KRYVWQGPTS | APILFPVTEE | 
    100:
    DPILSSFSRC | LKADVLGVWR | RDQRPGRREL | WIFWWGKDPN | FADLIHHDLS | 
    150:
    EEEDGVWENG | LSYECRTLLF | KAVHNLLERC | LMNRNFVRIG | KWFVKPYEKD | 
    200:
    EKPINKSEHL | SCSFTFFLHG | DSNVCTSVEI | NQHQPVYLLS | EEHVTLAQQS | 
    250:
    NSPFQVILSP | FGLNGTLTGQ | AFKMSDSATK | KLIGEWKQFY | PISCGLKEMS | 
    300:
    EEKQDDMDWE | DDSLAAVEVL | VAGVRMIYPA | CFVLVPQSDI | PAPSSVGASH | 
    350:
    CSASCLGIHQ | VPASTRDPAM | SSVTLTPPTS | PEEVQTVDPQ | SAQKWVKFSS | 
    400:
    VSDGFSTDST | SHHGGKIPRK | LANHVVDRVW | QECNMNRLQN | KRKYSATSSG | 
    450:
    LCEEETADKI | GCWDFVEATQ | RTSCSCLRHK | SLKTRNTGQQ | GQAPSLGQQQ | 
    500:
    QVLPKHKTNE | KQDKSEKPQK | RPLTPFHHRV | SVSDEIGMDT | DSASQRLVIS | 
    550:
    AADSQVRFSN | IRTNDVAKTP | QMHGTELANS | PQPPPLSPHP | CDVVDEGVTK | 
    600:
    TPSTPQSQHF | YQMPTPDPLV | PTKPMEDRID | SLSQSFPPPF | QEAVEPTVYV | 
    650:
    GTAVSLEEDE | ANVAWKYYKV | PKKKDVEFLP | PQLPNDKFKD | DPVGPFGQES | 
    700:
    VTSVTELMVQ | CKKPLKVSDE | IVQQYQIKNQ | YLSAIASDTE | QEPKIDPYAF | 
    750:
    VEGDEEFIFT | DKKDRQNSER | EAGKKHKVED | GTSAVTVLSH | EEDAMSLFSP | 
    800:
    SKQDAPRPTN | HARPPSTSLI | YDSDLAVSYT | DLDNLFNSDE | DELTPGSKKS | 
    850:
    ASGSDDKASS | KESKTGNLDP | LSCISTADLH | KMYPTPPSLE | QHIMGFSPMN | 
    900:
    MNNKEYGSVD | TAPGGTVLEG | NSSSVGTQFR | IEVEEGFCSP | KPSEIKDFSY | 
    950:
    VYKPENCQVL | VGCSMFAPLK | TLPSHCLPPI | KLPEECVYRQ | SWTVGKLDLL | 
    1000:
    PSGPSMPFIK | EGDGSNLDQD | YGPAYTPQTH | ASFGMPPSSA | PPSNGGAGIL | 
    1050:
    PSPSTPRFPT | PRTPRTPRTP | RGAGGPASAQ | GSVKYENSDL | YSPASTPSTC | 
    1100:
    RPLNSVEPAT | VPSIPEAHSL | YVNLILSESV | MNLFKDCNFD | SCCICVCNMN | 
    1150:
    IKGADVGVYI | PDPTQEAQYR | CTCGFSAVMN | RKFGNNSGLF | LEDELDIIGR | 
    1200:
    NTDCGKEAEK | RFEALRASSV | ENVNGGLKES | EKVPDELILL | LQDQCTNLFS | 
    1250:
    PFGAADQDPF | PKVGISSNWV | RVEERDCCSD | CCLALEHGRQ | FMDNMSGGKV | 
    1300:
    DEALVRSSCL | HPWAKQNDAS | VQCSQDILRM | LLSLQPVLQD | AIQKKRTVRP | 
    1350:
    WGVQGPLTWQ | QFHKMAGRGS | YGTDESPEPL | PIPTFLLGYD | YDFLVLSPFA | 
    1400:
    LPYWEKLMLE | PYGSQRDIAY | VVLCPENEAL | LNGARSFFRD | LTAIYESCRL | 
    1450:
    GQHRPISRLL | TDGIMKVGAT | ASKKLSEKFV | TEWFSQAADG | NNEAFSKLKL | 
    1500:
    YAQVCRYDLG | PYLASQPLDS | SLLSQPNLVA | PPNQSLVTAP | QMTNTGNANA | 
    1550:
    PSATLASAAS | STMTMTSGVP | ISTSVATANS | TLTTTSSSSS | SSLSSGVSSN | 
    1600:
    KLPSFPPFGS | MNTSGTGSMS | AQASTVQSGQ | LGGQQSSSLQ | AAGISGESAS | 
    1650:
    LPTQPHPDVS | ESTMDRDKVG | IPTDGDSHAI | TYPPAIVVYI | IDPFTYENKD | 
    1700:
    ESTNSSNVWT | LGLLRCFLEM | VQTLPPHIKS | TVSVQIVPCQ | YLLQPVKHDD | 
    1750:
    RQIYSQHLKS | LAFSVFTQCR | RPLPTSTNVK | TLTGFGPGLA | METALKSPDR | 
    1800:
    PECIRLYTPP | FILAPVKDKQ | TELGETFGEA | GQKYNVLFVG | YCLSHDQRWI | 
    1850:
    LASCTDLYGE | LLETCIINID | VPNRARRKKG | SARRFGLQKL | WEWCLGLVQM | 
    1900:
    SSLPWRVVIG | RLGRIGHGEL | KDWSCLLSRR | NLQSLSKRLK | DMCRMCGISA | 
    1950:
    ADSPSILSAC | LVAMEPQGSF | VIMPDSVSTG | SVFGRSTTLN | MQTPQLNTPQ | 
    2000:
    DTSCTHILVF | PTSASVQVAS | ATYTTENLDL | AFNPNNDGAD | GMGIFDLLDT | 
    2050:
    GDDLDPDIIN | ILPASPTASP | VHSPGSHYPH | GGDAGKGQGT | DRLLSTESHD | 
    2100:
    EVTNILQQPL | ALGYFVSTAK | AGPLPDWFWS | ACPQAQYQCP | LFLKASLHLH | 
    2150:
    VPSVQSDELL | HSKHSHPLDS | NQTSDVLRFV | LEQYNALSWL | TCDPAVQDRR | 
    2171:
    SCLPVHFVVL | NQLYNFIMNM | L
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Mediator of RNA polymerase II transcription subunit 13
    ELISA Kit for Mouse Mediator of RNA polymerase II transcription subunit 13
    CLIA Kit for Mouse Mediator of RNA polymerase II transcription subunit 13
    CLIA Kit for Mouse Mediator of RNA polymerase II transcription subunit 13
    Polyclonal Antibody for Mouse Mediator of RNA polymerase II transcription subunit 13
    Polyclonal Antibody for Mouse Mediator of RNA polymerase II transcription subunit 13
    Monoclonal Antibody for Mouse Mediator of RNA polymerase II transcription subunit 13
    Monoclonal Antibody for Mouse Mediator of RNA polymerase II transcription subunit 13
    Protein for Mouse Mediator of RNA polymerase II transcription subunit 13
    Protein for Mouse Mediator of RNA polymerase II transcription subunit 13

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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 931-2171
      strain: C57BL/6J.
      tissue: Thymus.
    3. 3.
      "Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Koseki H. , Hiraoka S. , Saga Y. , Nagase T. , Ohara O. , Koga H.
      DNA Res.10:167-180(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 803-2029
      tissue: Brain.
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