Med14 ELISA Kit for Mouse(Mus musculus) | EIAab.comMed14 ELISA Kit for Mouse(Mus musculus)

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Med14 (Gene name),

Mediator of RNA polymerase II transcription subunit 14 (Protein name ), MED14_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Med14(Crsp2;Gm641;Trap170);

Protein name:

Mediator of RNA polymerase II transcription subunit 14;

Alternative:

Mediator complex subunit 14;Cofactor required for Sp1 transcriptional activation subunit 2(CRSP complex subunit 2);Thyroid hormone receptor-associated protein complex 170 kDa component(Trap170);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP. Interacts with AR, ESR1, SREBF1 and STAT2 (By similarity). Interacts with GATA1.

Function:

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

1459

Sequence:

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1459:

LTLPPGGRP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.17616

Pfam:

PF08638

String:

A2ABV5

KEGG:

mmu:26896

Uniprot:

A2ABV5

FOR

ELISA Kit for Mouse Mediator of RNA polymerase II transcription subunit 14

CLIA Kit for Mouse Mediator of RNA polymerase II transcription subunit 14

Polyclonal Antibody for Mouse Mediator of RNA polymerase II transcription subunit 14

Monoclonal Antibody for Mouse Mediator of RNA polymerase II transcription subunit 14

Protein for Mouse Mediator of RNA polymerase II transcription subunit 14

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

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