MEIOB ELISA Kit for Human(Homo sapiens) | EIAab.comMEIOB ELISA Kit for Human(Homo sapiens)

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Index > Protein center > MEIOB(Gene name) > Human

MEIOB (Gene name),

Meiosis-specific with OB domain-containing protein (Protein name ), MEIOB_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

MEIOB(C16orf73);

Protein name:

Meiosis-specific with OB domain-containing protein;

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Component of a multiprotein complex with RPA2 and SPATA22.

Function:

Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity in vitro.

Subcellular Location:

Cytoplasm Nucleus Chromosome Co-localizes with the RPA complex on meiotic chromosome axes. Accumulates on resected DNA. Localization is dependent on SPATA22.

Protein Attributes:

Sequence length:

442

Sequence:

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