MEN1 ELISA Kit for Bovine(Bos taurus) | EIAab.comMEN1 ELISA Kit for Bovine(Bos taurus)

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Index > Protein center > MEN1(Gene name) > Bovine

MEN1 (Gene name),

Menin (Protein name ), MEN1_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

MEN1;

Protein name:

Menin;

Alternative:

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

Component of MLL-containing complexes (named MLL, ASCOM, MLL2/MLL3 or MLL3/MLL4 complex): at least composed ASH2L, RBBP5, DPY30, WDR5, one or several histone methyltransferases (MLL, MLL2, MLL3 and/or MLL4), and the facultative components MEN1, HCFC1, HCFC2, NCOA6, KDM6A, PAXIP1/PTIP and C16orf53/PA1. Interacts with POLR2A phosphorylated at 'Ser-5', but not with the unphosphorylated, nor 'Ser-2' phosphorylated POLR2A forms. Interacts with FANCD2 and DBF4. Interacts with SMAD3, but not with SMAD2, nor SMAD4. Directly interacts with NFKB1, NFKB2 and RELA. Interacts with JUND.

Function:

Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression. May be involved in DNA repair.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

610

Sequence:

50:

100:

150:

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250:

300:

350:

400:

450:

500:

550:

600:

610:

SFLKRQRKGL |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Bt.26871

KEGG:

bta:539431

STRING:

9913.ENSBTAP00000002705

String:

Q0P5I0

Pfam:

PF05053

Uniprot:

Q0P5I0

FOR

ELISA Kit for Bovine Menin

CLIA Kit for Bovine Menin

Polyclonal Antibody for Bovine Menin

Monoclonal Antibody for Bovine Menin

Protein for Bovine Menin

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

NIH - Mammalian Gene Collection (MGC) project
Submitted (2006-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: Hereford.
tissue: Fetal pons.

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