Mep1a ELISA Kit for Mouse(Mus musculus) | EIAab.comMep1a ELISA Kit for Mouse(Mus musculus)

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Mep1a (Gene name),

Meprin A subunit alpha (Protein name ), MEP1A_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Mep1a;

Protein name:

Meprin A subunit alpha;

Alternative:

MEP-1;Endopeptidase-2;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homotetramer consisting of disulfide-linked alpha subunits, homooligomer consisting of disulfide-linked alpha subunit homodimers, or heterotetramer of two alpha and two beta subunits formed by non-covalent association of two disulfide-linked heterodimers. Genetic factors determine which oligomer(s) will be formed (strain-specific). Interacts with MBL2 through its carbohydrate moiety. This interaction may inhibit its catalytic activity.

Function:

N/A

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

747

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

747:

HAFFYAGERC | QAMHVHGSLL | GLLIGCIAGL | IFLTFVTFST | TNGKLRQ

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

10090.ENSMUSP00000024707

Pfam:

PF01400

String:

P28825

KEGG:

mmu:17287

UniGene:

Mm.5346

SMR:

P28825

Uniprot:

P28825

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ELISA Kit for Mouse Meprin A subunit alpha

Cat.:

E2226h

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96T

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ELISA Kit for Mouse Meprin A subunit alpha

Cat.:

E2226r

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96T

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ELISA Kit for Mouse Meprin A subunit alpha

Cat.:

E2226m

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Manual:

Looking for manual.

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96T

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CLIA Kit for Mouse Meprin A subunit alpha

Cat.:

U2226r

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Meprin A subunit alpha

Cat.:

U2226h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Meprin A subunit alpha

Cat.:

U2226m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Meprin A subunit alpha

Cat.:

P2226Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Meprin A subunit alpha

Cat.:

P2226Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Meprin A subunit alpha

Cat.:

P2226Rb-m

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Meprin A subunit alpha

Protein for Mouse Meprin A subunit alpha

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The alpha subunit of meprin A. Molecular cloning and sequencing, differential expression in inbred mouse strains, and evidence for divergent evolution of the alpha and beta subunits."
Jiang W. , Gorbea C.M. , Flannery A.V. , Beynon R.J. , Grant G.A. , Bond J.S.
J. Biol. Chem.267:9185-9193(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 65-103; 107-122; 273-292; 314-348; 370-375; 377-386; 389-398 AND 527-557
strain: C3H/He.
strain: C57BL/6.
tissue: Kidney.
2.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: FVB/N.
tissue: Kidney.
4.

"Characterization of the soluble, secreted form of urinary meprin."
Beynon R.J. , Oliver S. , Robertson D.H.L.
Biochem. J.315:461-465(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-25 AND 65-69
5.

"Correlation of the exon/intron organization to the secondary structures of the protease domain of mouse meprin alpha subunit."
Jiang W. , Flannery A.V.
Gene189:65-71(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 62-258
strain: 129.
6.

"The astacin family of metalloendopeptidases."
Dumermuth E. , Sterchi E.E. , Jiang W. , Wolz R.L. , Bond J.S. , Flannery A.V. , Beynon R.J.
J. Biol. Chem.266:21381-21385(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 64-262
7.

"Meprin-A and -B. Cell surface endopeptidases of the mouse kidney."
Kounnas M.Z. , Wolz R.L. , Gorbea C.M. , Bond J.S.
J. Biol. Chem.266:17350-17357(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 65-72; 315-348 AND 529-546;ENZYME REGULATION;BIOPHYSICOCHEMICAL PROPERTIES;GLYCOSYLATION
strain: ICR.
tissue: Kidney.
8.

"Homo- and heterotetrameric forms of the membrane-bound metalloendopeptidases meprin A and B."
Gorbea C.M. , Flannery A.V. , Bond J.S.
Arch. Biochem. Biophys.290:549-553(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
9.

"Mapping the active site of meprin-A with peptide substrates and inhibitors."
Wolz R.L. , Harris R.B. , Bond J.S.
Biochemistry30:8488-8493(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;ENZYME REGULATION;BIOPHYSICOCHEMICAL PROPERTIES
10.

"Marked differences between metalloproteases meprin A and B in substrate and peptide bond specificity."
Bertenshaw G.P. , Turk B.E. , Hubbard S.J. , Matters G.L. , Bylander J.E. , Crisman J.M. , Cantley L.C. , Bond J.S.
J. Biol. Chem.276:13248-13255(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY
11.

"Mannan-binding protein blocks the activation of metalloproteases meprin alpha and beta."
Hirano M. , Ma B.Y. , Kawasaki N. , Okimura K. , Baba M. , Nakagawa T. , Miwa K. , Kawasaki N. , Oka S. , Kawasaki T.
J. Immunol.175:3177-3185(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MBL2
12.

"Protease domain glycans affect oligomerization, disulfide bond formation, and stability of the meprin A metalloprotease homo-oligomer."
Ishmael S.S. , Ishmael F.T. , Jones A.D. , Bond J.S.
J. Biol. Chem.281:37404-37415(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;GLYCOSYLATION AT ASN-28; ASN-139; ASN-221; ASN-257; ASN-317; ASN-413; ASN-439; ASN-533 AND ASN-540;MUTAGENESIS OF ASN-139; SER-141; ASN-221; ASN-257 AND THR-259
13.

"Human and mouse homo-oligomeric meprin A metalloendopeptidase: substrate and inhibitor specificities."
Bylander J.E. , Bertenshaw G.P. , Matters G.L. , Hubbard S.J. , Bond J.S.
Biol. Chem.388:1163-1172(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION;BIOPHYSICOCHEMICAL PROPERTIES
14.

"Implications of the three-dimensional structure of astacin for the structure and function of the astacin family of zinc-endopeptidases."
Stoecker W. , Gomis-Rueth F.-X. , Bode W. , Zwilling R.
Eur. J. Biochem.214:215-231(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: 3D-STRUCTURE MODELING

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