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Index > Protein center > Mgst1(Gene name) > Rat
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  • Mgst1 (Gene name),
  • Microsomal glutathione S-transferase 1 (Protein name ),  MGST1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Mgst1(Gst12);
    Protein name:
    Microsomal glutathione S-transferase 1(Microsomal GST-1);
    Alternative:
    Microsomal GST-I;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homotrimer; The trimer binds only one molecule of glutathione.
    Function:
    Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
    Subcellular Location:
    Microsome Mitochondrion outer membrane Peripheral membrane protein Endoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    155
    Sequence:
    50:
    MADLKQLMDN | EVLMAFTSYA | TIILAKMMFL | SSATAFQRLT | NKVFANPEDC | 
    100:
    AGFGKGENAK | KFLRTDEKVE | RVRRAHLNDL | ENIVPFLGIG | LLYSLSGPDL | 
    150:
    STALIHFRIF | VGARIYHTIA | YLTPLPQPNR | GLAFFVGYGV | TLSMAYRLLR | 
    155:
    SRLYL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Microsomal GST-1
    ELISA Kit for Rat Microsomal GST-1
    ELISA Kit for Rat Microsomal GST-1
    ELISA Kit for Rat Microsomal GST-1
    ELISA Kit for Rat Microsomal GST-1
    CLIA Kit for Rat Microsomal GST-1
    CLIA Kit for Rat Microsomal GST-1
    CLIA Kit for Rat Microsomal GST-1
    CLIA Kit for Rat Microsomal GST-1
    CLIA Kit for Rat Microsomal GST-1
    Polyclonal Antibody for Rat Microsomal GST-1
    Polyclonal Antibody for Rat Microsomal GST-1
    Polyclonal Antibody for Rat Microsomal GST-1
    Polyclonal Antibody for Rat Microsomal GST-1
    Polyclonal Antibody for Rat Microsomal GST-1
    Monoclonal Antibody for Rat Microsomal GST-1
    Monoclonal Antibody for Rat Microsomal GST-1
    Monoclonal Antibody for Rat Microsomal GST-1
    Monoclonal Antibody for Rat Microsomal GST-1
    Monoclonal Antibody for Rat Microsomal GST-1
    Protein for Rat Microsomal GST-1
    Protein for Rat Microsomal GST-1
    Protein for Rat Microsomal GST-1
    Protein for Rat Microsomal GST-1
    Protein for Rat Microsomal GST-1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Gene expression of rat and human microsomal glutathione S-transferases."
      Dejong J.L. , Morgenstern R. , Joernvall H. , Depierre J.W. , Tu C.-P.D.
      J. Biol. Chem.263:8430-8436(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Liver.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Pituitary.
    3. 3.
      "Microsomal glutathione transferase. Primary structure."
      Morgenstern R. , Depierre J.W. , Joernvall H.
      J. Biol. Chem.260:13976-13983(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-155
    4. 4.
      "The distribution of microsomal glutathione transferase among different organelles, different organs, and different organisms."
      Morgenstern R. , Lundqvist G. , Andersson G. , Balk L. , Depierre J.W.
      Biochem. Pharmacol.33:3609-3614(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
      strain: Sprague-Dawley.
      tissue: Liver.
    5. 5.
      "Reactivity of cysteine-49 and its influence on the activation of microsomal glutathione transferase 1: evidence for subunit interaction."
      Svensson R. , Rinaldi R. , Swedmark S. , Morgenstern R.
      Biochemistry39:15144-15149(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ROLE OF CYS-50 IN ENZYME REGULATION
    6. 6.
      "Nitration of tyrosine 92 mediates the activation of rat microsomal glutathione s-transferase by peroxynitrite."
      Ji Y. , Neverova I. , Van Eyk J.E. , Bennett B.M.
      J. Biol. Chem.281:1986-1991(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NITRATION AT TYR-93;ENZYME REGULATION
    7. 7.
      "Structural basis for detoxification and oxidative stress protection in membranes."
      Holm P.J. , Bhakat P. , Jegerschold C. , Gyobu N. , Mitsuoka K. , Fujiyoshi Y. , Morgenstern R. , Hebert H.
      J. Mol. Biol.360:934-945(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS) OF 2-154 IN COMPLEX WITH GLUTATHIONE;SUBUNIT;SUBCELLULAR LOCATION;MEMBRANE TOPOLOGY;MUTAGENESIS OF HIS-76 AND GLU-81;GLUTATHIONE BINDING SITES
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