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Index > Protein center > MGAT4B(Gene name) > Human
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  • MGAT4B (Gene name),
  • Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B (Protein name ),  MGT4B_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    MGAT4B(UNQ906/PRO1927);
    Protein name:
    Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B;
    Alternative:
    UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb;N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb(GlcNAc-T IVb;GnT-IVb;N-acetylglucosaminyltransferase IVb);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis.
    Subcellular Location:
    Golgi apparatus membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    548
    Sequence:
    50:
    MRLRNGTFLT | LLLFCLCAFL | SLSWYAALSG | QKGDVVDVYQ | REFLALRDRL | 
    100:
    HAAEQESLKR | SKELNLVLDE | IKRAVSERQA | LRDGDGNRTW | GRLTEDPRLK | 
    150:
    PWNGSHRHVL | HLPTVFHHLP | HLLAKESSLQ | PAVRVGQGRT | GVSVVMGIPS | 
    200:
    VRREVHSYLT | DTLHSLISEL | SPQEKEDSVI | VVLIAETDSQ | YTSAVTENIK | 
    250:
    ALFPTEIHSG | LLEVISPSPH | FYPDFSRLRE | SFGDPKERVR | WRTKQNLDYC | 
    300:
    FLMMYAQSKG | IYYVQLEDDI | VAKPNYLSTM | KNFALQQPSE | DWMILEFSQL | 
    350:
    GFIGKMFKSL | DLSLIVEFIL | MFYRDKPIDW | LLDHILWVKV | CNPEKDAKHC | 
    400:
    DRQKANLRIR | FKPSLFQHVG | THSSLAGKIQ | KLKDKDFGKQ | ALRKEHVNPP | 
    450:
    AEVSTSLKTY | QHFTLEKAYL | REDFFWAFTP | AAGDFIRFRF | FQPLRLERFF | 
    500:
    FRSGNIEHPE | DKLFNTSVEV | LPFDNPQSDK | EALQEGRTAT | LRYPRSPDGY | 
    548:
    LQIGSFYKGV | AEGEVDPAFG | PLEALRLSIQ | TDSPVWVILS | EIFLKKAD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    UniGene:
    String:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
    ELISA Kit for Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
    CLIA Kit for Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
    CLIA Kit for Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
    Polyclonal Antibody for Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
    Polyclonal Antibody for Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
    Monoclonal Antibody for Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
    Monoclonal Antibody for Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
    Protein for Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
    Protein for Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "A novel second isoenzyme of the human UDP-N-acetylglucosamine:alpha1,3-D-mannoside beta1,4-N-acetylglucosaminyltransferase family: cDNA cloning, expression, and chromosomal assignment."
      Yoshida A. , Minowa M.T. , Takamatsu S. , Hara T. , Ikenaga H. , Takeuchi M.
      Glycoconj. J.15:1115-1123(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
      tissue: Lung.
    2. 2.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)
    4. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT PHE-491
      tissue: PNS.
      tissue: Uterus.
    6. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 176-548 (ISOFORM 2)
      tissue: Melanoma.
    7. 8.
      "Aberrant expression of N-acetylglucosaminyltransferase-IVa and IVb (GnT-IVa and b) in pancreatic cancer."
      Ide Y. , Miyoshi E. , Nakagawa T. , Gu J. , Tanemura M. , Nishida T. , Ito T. , Yamamoto H. , Kozutsumi Y. , Taniguchi N.
      Biochem. Biophys. Res. Commun.341:478-482(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: OVEREXPRESSION IN PANCREATIC CANCER
    8. 9.
      "Kinetic properties and substrate specificities of two recombinant human N-acetylglucosaminyltransferase-IV isozymes."
      Oguri S. , Yoshida A. , Minowa M.T. , Takeuchi M.
      Glycoconj. J.23:473-480(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME ACTIVITY;BIOPHYSICOCHEMICAL PROPERTIES
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