Gene name:
MGAT4B (UNQ906/PRO1927) ;
Protein name:
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B ;
Alternative:
UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IVb ;N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVb (GlcNAc-T IVb;GnT-IVb;N-acetylglucosaminyltransferase IVb) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis.
Subcellular Location:
Golgi apparatus membrane
Single-pass type II membrane protein
Protein Attributes:
50:
MRLRNGTFLT | LLLFCLCAFL | SLSWYAALSG | QKGDVVDVYQ | REFLALRDRL |
100:
HAAEQESLKR | SKELNLVLDE | IKRAVSERQA | LRDGDGNRTW | GRLTEDPRLK |
150:
PWNGSHRHVL | HLPTVFHHLP | HLLAKESSLQ | PAVRVGQGRT | GVSVVMGIPS |
200:
VRREVHSYLT | DTLHSLISEL | SPQEKEDSVI | VVLIAETDSQ | YTSAVTENIK |
250:
ALFPTEIHSG | LLEVISPSPH | FYPDFSRLRE | SFGDPKERVR | WRTKQNLDYC |
300:
FLMMYAQSKG | IYYVQLEDDI | VAKPNYLSTM | KNFALQQPSE | DWMILEFSQL |
350:
GFIGKMFKSL | DLSLIVEFIL | MFYRDKPIDW | LLDHILWVKV | CNPEKDAKHC |
400:
DRQKANLRIR | FKPSLFQHVG | THSSLAGKIQ | KLKDKDFGKQ | ALRKEHVNPP |
450:
AEVSTSLKTY | QHFTLEKAYL | REDFFWAFTP | AAGDFIRFRF | FQPLRLERFF |
500:
FRSGNIEHPE | DKLFNTSVEV | LPFDNPQSDK | EALQEGRTAT | LRYPRSPDGY |
548:
LQIGSFYKGV | AEGEVDPAFG | PLEALRLSIQ | TDSPVWVILS | EIFLKKAD
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
ELISA Kit for Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
CLIA Kit for Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
CLIA Kit for Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
Polyclonal Antibody for Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
Polyclonal Antibody for Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
Monoclonal Antibody for Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
Monoclonal Antibody for Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
Protein for Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
Protein for Human Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
R&D Technical Data
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Precision
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Recovery
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Linearity
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Lung .
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