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Index > Protein center > Mib2(Gene name) > Rat
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  • Mib2 (Gene name),
  • E3 ubiquitin-protein ligase MIB2 (Protein name ),  MIB2_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Mib2;
    Protein name:
    E3 ubiquitin-protein ligase MIB2;
    Alternative:
    RBSC-skeletrophin/dystrophin-like polypeptide;Mind bomb homolog 2;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with actin monomer.
    Function:
    E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.
    Subcellular Location:
    Cytoplasm Endosome Colocalizes with endosomal compartments.
    Protein Attributes:
    Sequence length:
    971
    Sequence:
    50:
    MDLDPHAGVQ | VGMRVVRGMD | WKWGQQDGGE | GGVGTVVELG | RHGSPSTPDR | 
    100:
    TVVVQWDQGT | RTNYRAGYQG | AHDLLLYDNA | QIGIRHPNII | CDCCKKHGLR | 
    150:
    GMRWKCRVCF | DYDLCTQCYM | HNKHDLTHAF | ERYETSHSRP | VTLSPRQGLP | 
    200:
    RIPLRGIFQG | AKVVRGPDWE | WGSQDGGEGK | TGRVVDIRGW | DVETGRSVAS | 
    250:
    VTWADGTTNV | YRVGHKGKVD | LKCVGEAAGG | FYYKEHLPKL | GKPAELQRRV | 
    300:
    SADGQPFQRG | DKVKCLLDTD | VLRDMQEGHG | GWNPRMAEFI | GQMGTVHRIT | 
    350:
    DRGDVRVQFN | HETRWTFHPG | ALTKHNSFWV | GDVVRVIDDL | DTVKRLQAGH | 
    400:
    GEWTDDMAPA | LGRVGKVVKV | FGDGNLRVAV | GGQRWTFSPA | CLVACRPEED | 
    450:
    ANLGVAERAR | ENKSAASVPV | AGSLSVALDK | LRTQKSDPEH | PGRLVVEAAL | 
    500:
    GNVARALDLL | RRHPEQAGFH | PAVDTKNQGR | TALQVAAYLG | QVELVRLLLQ | 
    550:
    ARASVDLLDE | EGNTALHYTA | MGNQPEATRL | LLSAGCGVDA | QNGTRSTALH | 
    600:
    VAVQRGFLEV | VKILCEHGCD | VNLPDAHADT | PLHSAISAGA | GASSIVEVLT | 
    650:
    EVPGIDVTAT | NSQGFTLLHH | ASLKGHVLAV | RKILARARQL | VDAKKEDGFT | 
    700:
    ALHLAALNNH | REVAQVLIRE | GRCDVNVRNR | KLQSPLHLAV | QQAHLGLVPL | 
    750:
    LVDAGCNVNT | EDEEGDTALH | VALQRHQLLP | LVADRAGGDP | GPLQLLSRLQ | 
    800:
    ASGLPGSTEL | TVGAAVACFL | ALEGADVSYA | NHRGRSPLDL | ATEGRVLKAL | 
    850:
    QGCAQRFRER | QAGGGGGVPP | GPRHVLSTPN | TVTNLHVSGT | AGPEAAECLV | 
    900:
    CSELALLVLF | SPCQHRTVCE | ECARRMKKCI | RCQVIISKKL | RPDGSEVVNA | 
    950:
    IQVPGPPRQL | VEELQSRYRQ | MEERITCPIC | IDSHIRLVFQ | CGHGACAPCG | 
    971:
    AALNACPICR | QPIRDRIQIF | V
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat E3 ubiquitin-protein ligase MIB2
    ELISA Kit for Rat E3 ubiquitin-protein ligase MIB2
    ELISA Kit for Rat E3 ubiquitin-protein ligase MIB2
    ELISA Kit for Rat E3 ubiquitin-protein ligase MIB2
    CLIA Kit for Rat E3 ubiquitin-protein ligase MIB2
    CLIA Kit for Rat E3 ubiquitin-protein ligase MIB2
    CLIA Kit for Rat E3 ubiquitin-protein ligase MIB2
    CLIA Kit for Rat E3 ubiquitin-protein ligase MIB2
    Polyclonal Antibody for Rat E3 ubiquitin-protein ligase MIB2
    Polyclonal Antibody for Rat E3 ubiquitin-protein ligase MIB2
    Polyclonal Antibody for Rat E3 ubiquitin-protein ligase MIB2
    Polyclonal Antibody for Rat E3 ubiquitin-protein ligase MIB2
    Monoclonal Antibody for Rat E3 ubiquitin-protein ligase MIB2
    Monoclonal Antibody for Rat E3 ubiquitin-protein ligase MIB2
    Monoclonal Antibody for Rat E3 ubiquitin-protein ligase MIB2
    Monoclonal Antibody for Rat E3 ubiquitin-protein ligase MIB2
    Protein for Rat E3 ubiquitin-protein ligase MIB2
    Protein for Rat E3 ubiquitin-protein ligase MIB2
    Protein for Rat E3 ubiquitin-protein ligase MIB2
    Protein for Rat E3 ubiquitin-protein ligase MIB2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Gibbs R.A. , Weinstock G.M. , Metzker M.L. , Muzny D.M. , Sodergren E.J. , Scherer S. , Scott G. , Steffen D. , Worley K.C. , Burch P.E. , Okwuonu G. , Hines S. , Lewis L. , Deramo C. , Delgado O. , Dugan-Rocha S. , Miner G. , Morgan M. , more...
      Nature428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-85
      strain: Sprague-Dawley.
      tissue: Brain stem.
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