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Index > Protein center > MICU2(Gene name) > Human
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  • MICU2 (Gene name),
  • Calcium uptake protein 2, mitochondrial (Protein name ),  MICU2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    MICU2(EFHA1);
    Protein name:
    Calcium uptake protein 2, mitochondrial;
    Alternative:
    EF-hand domain-containing family member A1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Component of the uniplex complex, composed of MCU, MCUB, MICU1, MICU2 and EMRE/SMDT1.
    Function:
    Involved in mitochondrial uniporter-mediated calcium uptake. Probable regulator of the mitochondrial calcium uniporter (MCU).
    Subcellular Location:
    Mitochondrion intermembrane space
    Protein Attributes:
    Sequence length:
    434
    Sequence:
    50:
    MAAAAGSCAR | VAAWGGKLRR | GLAVSRQAVR | SPGPLAAAVA | GAALAGAGAA | 
    100:
    WHHSRVSVAA | RDGSFTVSAQ | KNVEHGIIYI | GKPSLRKQRF | MQFSSLEHEG | 
    150:
    EYYMTPRDFL | FSVMFEQMER | KTSVKKLTKK | DIEDTLSGIQ | TAGCGSTFFR | 
    200:
    DLGDKGLISY | TEYLFLLTIL | TKPHSGFHVA | FKMLDTDGNE | MIEKREFFKL | 
    250:
    QKIISKQDDL | MTVKTNETGY | QEAIVKEPEI | NTTLQMRFFG | KRGQRKLHYK | 
    300:
    EFRRFMENLQ | TEIQEMEFLQ | FSKGLSFMRK | EDFAEWLLFF | TNTENKDIYW | 
    350:
    KNVREKLSAG | ESISLDEFKS | FCHFTTHLED | FAIAMQMFSL | AHRPVRLAEF | 
    400:
    KRAVKVATGQ | ELSNNILDTV | FKIFDLDGDE | CLSHEEFLGV | LKNRMHRGLW | 
    434:
    VPQHQSIQEY | WKCVKKESIK | GVKEVWKQAG | KGLF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Calcium uptake protein 2, mitochondrial
    ELISA Kit for Human Calcium uptake protein 2, mitochondrial
    ELISA Kit for Human Calcium uptake protein 2, mitochondrial
    CLIA Kit for Human Calcium uptake protein 2, mitochondrial
    CLIA Kit for Human Calcium uptake protein 2, mitochondrial
    CLIA Kit for Human Calcium uptake protein 2, mitochondrial
    Polyclonal Antibody for Human Calcium uptake protein 2, mitochondrial
    Polyclonal Antibody for Human Calcium uptake protein 2, mitochondrial
    Polyclonal Antibody for Human Calcium uptake protein 2, mitochondrial
    Monoclonal Antibody for Human Calcium uptake protein 2, mitochondrial
    Monoclonal Antibody for Human Calcium uptake protein 2, mitochondrial
    Monoclonal Antibody for Human Calcium uptake protein 2, mitochondrial
    Protein for Human Calcium uptake protein 2, mitochondrial
    Protein for Human Calcium uptake protein 2, mitochondrial
    Protein for Human Calcium uptake protein 2, mitochondrial

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    Precision
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    Linearity
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    References
    1. 1.
      "The DNA sequence and analysis of human chromosome 13."
      Dunham A. , Matthews L.H. , Burton J. , Ashurst J.L. , Howe K.L. , Ashcroft K.J. , Beare D.M. , Burford D.C. , Hunt S.E. , Griffiths-Jones S. , Jones M.C. , Keenan S.J. , Oliver K. , Scott C.E. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews D.T. , more...
      Nature428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT LEU-260
      tissue: Brain.
      tissue: Testis.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 61-434
      tissue: Kidney.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-205;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;IDENTIFICATION IN THE UNIPLEX COMPLEX
    7. 7.
      "MICU1 and MICU2 play nonredundant roles in the regulation of the mitochondrial calcium uniporter."
      Kamer K.J. , Mootha V.K.
      EMBO Rep.15:299-307(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF ASP-185; ASP-375 AND GLU-386
    8. 8.
      "MICU1 and MICU2 finely tune the mitochondrial Ca(2+) uniporter by exerting opposite effects on MCU activity."
      Patron M. , Checchetto V. , Raffaello A. , Teardo E. , Vecellio Reane D. , Mantoan M. , Granatiero V. , Szabo I. , De Stefani D. , Rizzuto R.
      Mol. Cell53:726-737(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH MICU1
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