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Index > Protein center > MIEN1(Gene name) > Human
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  • MIEN1 (Gene name),
  • Migration and invasion enhancer 1 (Protein name ),  MIEN1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    MIEN1(C17orf37;RDX12;XTP4);
    Protein name:
    Migration and invasion enhancer 1;
    Alternative:
    HBV XAg-transactivated protein 4;HBV X-transactivated gene 4 protein;Protein C35;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with GPX1.
    Function:
    Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process.
    Subcellular Location:
    Cytoplasm Cytosol Cell membrane Lipid-anchor Cytoplasmic side Concentrates at the leading edge of migrating cells. Localizes outside membrane raft regions.
    Protein Attributes:
    Sequence length:
    115
    Sequence:
    50:
    MSGEPGQTSV | APPPEEVEPG | SGVRIVVEYC | EPCGFEATYL | ELASAVKEQY | 
    100:
    PGIEIESRLG | GTGAFEIEIN | GQLVFSKLEN | GGFPYEKDLI | EAIRRASNGE | 
    115:
    TLEKITNSRP | PCVIL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    MIM:
    UniGene:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Migration and invasion enhancer 1
    ELISA Kit for Human Migration and invasion enhancer 1
    ELISA Kit for Human Migration and invasion enhancer 1
    CLIA Kit for Human Migration and invasion enhancer 1
    CLIA Kit for Human Migration and invasion enhancer 1
    CLIA Kit for Human Migration and invasion enhancer 1
    Polyclonal Antibody for Human Migration and invasion enhancer 1
    Polyclonal Antibody for Human Migration and invasion enhancer 1
    Polyclonal Antibody for Human Migration and invasion enhancer 1
    Monoclonal Antibody for Human Migration and invasion enhancer 1
    Monoclonal Antibody for Human Migration and invasion enhancer 1
    Monoclonal Antibody for Human Migration and invasion enhancer 1
    Protein for Human Migration and invasion enhancer 1
    Protein for Human Migration and invasion enhancer 1
    Protein for Human Migration and invasion enhancer 1

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    Linearity
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    References
    1. 1.
      "C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer."
      Evans E.E. , Henn A.D. , Jonason A. , Paris M.J. , Schiffhauer L.M. , Borrello M.A. , Smith E.S. , Sahasrabudhe D.M. , Zauderer M.
      Mol. Cancer Ther.5:2919-2930(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;SUBCELLULAR LOCATION;ISOPRENYLATION
    2. 2.
      "Cloning and identification of human gene 4 transactivated by hepatitis B virus X antigen."
      Liu Y. , Cheng J. , Lu Y. , Wang G. , Zhang L. , Chen J. , Li L.
      Submitted (2002-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    4. 5.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
    5. 6.
      "Novel gene C17orf37 in 17q12 amplicon promotes migration and invasion of prostate cancer cells."
      Dasgupta S. , Wasson L.M. , Rauniyar N. , Prokai L. , Borejdo J. , Vishwanatha J.K.
      Oncogene28:2860-2872(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;ISOPRENYLATION AT CYS-112
    6. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    7. 8.
      "Prenylated c17orf37 induces filopodia formation to promote cell migration and metastasis."
      Dasgupta S. , Cushman I. , Kpetemey M. , Casey P.J. , Vishwanatha J.K.
      J. Biol. Chem.286:25935-25946(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;ISOPRENYLATION AT CYS-112;MUTAGENESIS OF CYS-112 AND 112-CYS--LEU-115
    8. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 10.
      "Solution structure of the oncogenic MIEN1 protein reveals a thioredoxin-like fold with a redox-active motif."
      Hsu C.H. , Shen T.L. , Chang C.F. , Chang Y.Y. , Huang L.Y.
      PLoS ONE7:E52292-E52292(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR;DISULFIDE BOND
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