Protein name:
Microphthalmia-associated transcription factor ;
Alternative:
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA in the form of homodimer or heterodimer with either TFE3, TFEB or TFEC. Interacts with KARS.
Function:
Transcription factor for tyrosinase and tyrosinase-related protein 1. Binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') found in the tyrosinase promoter. Plays a critical role in the differentiation of various cell types as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.
Subcellular Location:
Nucleus
Protein Attributes:
50:
LTACIFPTES | EARALAKERQ | KKDNHNLIER | RRRFNINDRI | KELGTLIPKS |
100:
NDPDMRWNKG | TILKASVDYI | RKLQREQQRA | KDLENRQKKL | EHANRHLLLR |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
ELISA Kit for Rat Microphthalmia-associated transcription factor
ELISA Kit for Rat Microphthalmia-associated transcription factor
ELISA Kit for Rat Microphthalmia-associated transcription factor
CLIA Kit for Rat Microphthalmia-associated transcription factor
CLIA Kit for Rat Microphthalmia-associated transcription factor
CLIA Kit for Rat Microphthalmia-associated transcription factor
Polyclonal Antibody for Rat Microphthalmia-associated transcription factor
Polyclonal Antibody for Rat Microphthalmia-associated transcription factor
Polyclonal Antibody for Rat Microphthalmia-associated transcription factor
Monoclonal Antibody for Rat Microphthalmia-associated transcription factor
Monoclonal Antibody for Rat Microphthalmia-associated transcription factor
Monoclonal Antibody for Rat Microphthalmia-associated transcription factor
Protein for Rat Microphthalmia-associated transcription factor
Protein for Rat Microphthalmia-associated transcription factor
Protein for Rat Microphthalmia-associated transcription factor
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]