Mdk ELISA Kit for Mouse(Mus musculus) | EIAab.comMdk ELISA Kit for Mouse(Mus musculus)

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Mdk (Gene name),

Midkine (Protein name ), MK_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Mdk(Mk);

Protein name:

Midkine(MK);

Alternative:

Retinoic acid-induced differentiation factor;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer (By similarity). Interacts with ALK.

Function:

Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation (By similarity). Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

140

Sequence:

50:

100:

140:

QGTLKKARYN | AQCQETIRVT | KPCTSKTKSK | TKAKKGKGKD |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.906

KEGG:

mmu:17242

Pfam:

PF01091

SMR:

P12025

String:

P12025

Uniprot:

P12025

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ELISA Kit for Mouse MK

Cat.:

E0631m

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Packing:

96T

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ELISA Kit for Mouse MK

Cat.:

E0631h

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Packing:

96T

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ELISA Kit for Mouse MK

Cat.:

E0631r

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96T

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CLIA Kit for Mouse MK

Cat.:

U0631r

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MSDS:

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Packing:

96T

CLIA Kit for Mouse MK

Cat.:

U0631h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Mouse MK

Cat.:

U0631m

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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Polyclonal Antibody for Mouse MK

Cat.:

P0631Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse MK

Cat.:

P0631Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse MK

Cat.:

P0631Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse MK

Protein for Mouse MK

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Structure of a retinoic acid-responsive gene, MK, which is transiently activated during the differentiation of embryonal carcinoma cells and the mid-gestation period of mouse embryogenesis."
Matsubara S. , Tomomura M. , Kadomatsu K. , Muramatsu T.
J. Biol. Chem.265:9441-9443(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
2.

"A retinoic acid-responsive gene, MK, found in the teratocarcinoma system. Heterogeneity of the transcript and the nature of the translation product."
Tomomura M. , Kadomatsu K. , Matsubara S. , Muramatsu T.
J. Biol. Chem.265:10765-10770(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"cDNA cloning and sequencing of a new gene intensely expressed in early differentiation stages of embryonal carcinoma cells and in mid-gestation period of mouse embryogenesis."
Kadomatsu K. , Tomomura M. , Muramatsu T.
Biochem. Biophys. Res. Commun.151:1312-1318(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: FVB/N.
tissue: Salivary gland.
5.

"Midkine, a heparin-binding growth/differentiation factor, exhibits nerve cell adhesion and guidance activity for neurite outgrowth in vitro."
Kaneda N. , Talukder A.H. , Nishiyama H. , Koizumi S. , Muramatsu T.
J. Biochem.119:1150-1156(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 1-42
6.

"Neointima formation in a restenosis model is suppressed in midkine-deficient mice."
Horiba M. , Kadomatsu K. , Nakamura E. , Muramatsu H. , Ikematsu S. , Sakuma S. , Hayashi K. , Yuzawa Y. , Matsuo S. , Kuzuya M. , Kaname T. , Hirai M. , Saito H. , Muramatsu T.
J. Clin. Invest.105:489-495(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

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