MLH3 ELISA Kit for Human(Homo sapiens) | EIAab.comMLH3 ELISA Kit for Human(Homo sapiens)

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MLH3 (Gene name),

DNA mismatch repair protein Mlh3 (Protein name ), MLH3_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

MLH3;

Protein name:

DNA mismatch repair protein Mlh3;

Alternative:

MutL protein homolog 3;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Heterodimer of MLH1 and MLH3. Interacts with MTMR15/FAN1.

Function:

Probably involved in the repair of mismatches in DNA.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

1453

Sequence:

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1400:

1450:

1453:

EPP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000348020

Pfam:

PF01119

KEGG:

hsa:27030

SMR:

Q9UHC1

String:

Q9UHC1

MIM:

114500

UniGene:

Hs.436650

Uniprot:

Q9UHC1

FOR

ELISA Kit for Human DNA mismatch repair protein Mlh3

CLIA Kit for Human DNA mismatch repair protein Mlh3

Polyclonal Antibody for Human DNA mismatch repair protein Mlh3

Monoclonal Antibody for Human DNA mismatch repair protein Mlh3

Protein for Human DNA mismatch repair protein Mlh3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"MLH3: a DNA mismatch repair gene associated with mammalian microsatellite instability."
Lipkin S.M. , Wang V. , Jacoby R. , Banerjee-Basu S. , Baxevanis A.D. , Lynch H.T. , Elliott R.M. , Collins F.S.
Nat. Genet.24:27-35(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA];ALTERNATIVE SPLICING;VARIANTS ASP-826 AND LEU-844
2.

"The interacting domains of three MutL heterodimers in man: hMLH1 interacts with 36 homologous amino acid residues within hMLH3, hPMS1 and hPMS2."
Kondo E. , Horii A. , Fukushige S.
Nucleic Acids Res.29:1695-1702(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH MLH1;VARIANT ASP-826
3.

NIEHS SNPs program
Submitted (2005-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS GLY-93; SER-120; GLN-231; ILE-420; VAL-492; GLN-600; PRO-606; GLN-624; CYS-647; CYS-720; ILE-723; PHE-741; HIS-797; ASP-826; LEU-844; GLY-845; ILE-942; PRO-966; ASN-1073; GLU-1105; ASP-1163 AND ARG-1319
4.

"The DNA sequence and analysis of human chromosome 14."
Heilig R. , Eckenberg R. , Petit J.-L. , Fonknechten N. , Da Silva C. , Cattolico L. , Levy M. , Barbe V. , De Berardinis V. , Ureta-Vidal A. , Pelletier E. , Vico V. , Anthouard V. , Rowen L. , Madan A. , Qin S. , Sun H. , Du H. , more...
Nature421:601-607(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease."
Sherrington R. , Rogaev E.I. , Liang Y. , Rogaeva E.A. , Levesque G. , Ikeda M. , Chi H. , Lin C. , Li G. , Holman K. , Tsuda T. , Mar L. , Foncin J.-F. , Bruni A.C. , Montesi M.P. , Sorbi S. , Rainero I. , Pinessi L. , more...
Nature375:754-760(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1189-1453
tissue: Brain.
6.

"Germline and somatic mutation analyses in the DNA mismatch repair gene MLH3: evidence for somatic mutation in colorectal cancers."
Lipkin S.M. , Wang V. , Stoler D.L. , Anderson G.R. , Kirsch I. , Hadley D. , Lynch H.T. , Collins F.S.
Hum. Mutat.17:389-396(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN SOMATIC COLORECTAL CANCER
7.

"A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair."
Smogorzewska A. , Desetty R. , Saito T.T. , Schlabach M. , Lach F.P. , Sowa M.E. , Clark A.B. , Kunkel T.A. , Harper J.W. , Colaiacovo M.P. , Elledge S.J.
Mol. Cell39:36-47(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MTMR15
8.

"A role for MLH3 in hereditary nonpolyposis colorectal cancer."
Wu Y. , Berends M.J.W. , Sijmons R.H. , Mensink R.G.J. , Verlind E. , Kooi K.A. , van der Sluis T. , Kempinga C. , van der Zee A.G.J. , Hollema H. , Buys C.H.C.M. , Kleibeuker J.H. , Hofstra R.M.W.
Nat. Genet.29:137-138(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HNPCC7 GLU-24; SER-499; GLN-624; CYS-647; GLY-817; SER-981; SER-1007; THR-1394 AND LYS-1451

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