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Index > Protein center > MPHOSPH10(Gene name) > Human
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  • MPHOSPH10 (Gene name),
  • U3 small nucleolar ribonucleoprotein protein MPP10 (Protein name ),  MPP10_HUMAN from NCBI database.
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  • General Annotation
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  • Gene name:
    MPHOSPH10(MPP10);
    Protein name:
    U3 small nucleolar ribonucleoprotein protein MPP10;
    Alternative:
    M phase phosphoprotein 10;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Component of a heterotrimeric complex containing IMP3, IMP4 and MPHOSPH10. Interacts with IMP3 and IMP4.
    Function:
    Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
    Subcellular Location:
    Nucleus nucleolus Chromosome Fibrillar region of the nucleolus. After dissolution of the nucleolus in early M phase becomes associated with chromosomes through metaphase and anaphase. In telophase localized to small cellular prenucleolar bodies that not always contain fibrillarin. The reassociation with nucleolus is preceeded by the arrival of fibrillarin.
    Protein Attributes:
    Sequence length:
    681
    Sequence:
    50:
    MAPQVWRRRT | LERCLTEVGK | ATGRPECFLT | IQEGLASKFT | SLTKVLYDFN | 
    100:
    KILENGRIHG | SPLQKLVIEN | FDDEQIWQQL | ELQNEPILQY | FQNAVSETIN | 
    150:
    DEDISLLPES | EEQEREEDGS | EIEADDKEDL | EDLEEEEVSD | MGNDDPEMGE | 
    200:
    RAENSSKSDL | RKSPVFSDED | SDLDFDISKL | EQQSKVQNKG | QGKPREKSIV | 
    250:
    DDKFFKLSEM | EAYLENIEKE | EERKDDNDEE | EEDIDFFEDI | DSDEDEGGLF | 
    300:
    GSKKLKSGKS | SRNLKYKDFF | DPVESDEDIT | NVHDDELDSN | KEDDEIAEEE | 
    350:
    AEELSISETD | EDDDLQENED | NKQHKESLKR | VTFALPDDAE | TEDTGVLNVK | 
    400:
    KNSDEVKSSF | EKRQEKMNEK | IASLEKELLE | KKPWQLQGEV | TAQKRPENSL | 
    450:
    LEETLHFDHA | VRMAPVITEE | TTLQLEDIIK | QRIRDQAWDD | VVRKEKPKED | 
    500:
    AYEYKKRLTL | DHEKSKLSLA | EIYEQEYIKL | NQQKTAEEEN | PEHVEIQKMM | 
    550:
    DSLFLKLDAL | SNFHFIPKPP | VPEIKVVSNL | PAITMEEVAP | VSVSDAALLA | 
    600:
    PEEIKEKNKA | GDIKTAAEKT | ATDKKRERRK | KKYQKRMKIK | EKEKRRKLLE | 
    650:
    KSSVDQAGKY | SKTVASEKLK | QLTKTGKASF | IKDEGKDKAL | KSSQAFFSKL | 
    681:
    QDQVKMQIND | AKKTEKKKKK | RQDISVHKLK | L
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    Pfam:
    UniGene:
    MIM:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human U3 small nucleolar ribonucleoprotein protein MPP10
    ELISA Kit for Human U3 small nucleolar ribonucleoprotein protein MPP10
    CLIA Kit for Human U3 small nucleolar ribonucleoprotein protein MPP10
    CLIA Kit for Human U3 small nucleolar ribonucleoprotein protein MPP10
    Polyclonal Antibody for Human U3 small nucleolar ribonucleoprotein protein MPP10
    Polyclonal Antibody for Human U3 small nucleolar ribonucleoprotein protein MPP10
    Monoclonal Antibody for Human U3 small nucleolar ribonucleoprotein protein MPP10
    Monoclonal Antibody for Human U3 small nucleolar ribonucleoprotein protein MPP10
    Protein for Human U3 small nucleolar ribonucleoprotein protein MPP10
    Protein for Human U3 small nucleolar ribonucleoprotein protein MPP10

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Identification of novel M phase phosphoproteins by expression cloning."
      Matsumoto-Taniura N. , Pirollet F. , Monroe R. , Gerace L. , Westendorf J.M.
      Mol. Biol. Cell7:1455-1469(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 10-681
      tissue: Blood.
    2. 2.
      "M phase phosphoprotein 10 is a human U3 small nucleolar ribonucleoprotein component."
      Westendorf J.M. , Konstantinov K.N. , Wormsley S. , Shu M.-D. , Matsumoto-Taniura N. , Pirollet F. , Klier F.G. , Gerace L. , Baserga S.J.
      Mol. Biol. Cell9:437-449(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Mammary cancer.
      tissue: Placenta.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    5. 5.
      "The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes."
      Granneman S. , Gallagher J.E.G. , Vogelzangs J. , Horstman W. , van Venrooij W.J. , Baserga S.J. , Pruijn G.J.M.
      Nucleic Acids Res.31:1877-1887(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH IMP3 AND IMP4
    6. 6.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-163; SER-167; SER-171; SER-242; SER-275 AND SER-289;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-163; SER-167; SER-171 AND SER-242;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    8. 8.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-167; SER-171 AND SER-242;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    9. 9.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-609;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-120; SER-139; SER-163; SER-167; SER-171 AND SER-242;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 11.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-120; SER-139; SER-163; SER-167; SER-171; SER-242; SER-275 AND SER-289;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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