Protein name:
MAGUK p55 subfamily member 5 ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with CRB3, LIN7C and MPDZ. Interacts with INADL, PARD6B, SC6A1 and EZR (By similarity). Forms a complex with CRB1 and MPP4. Component of a complex whose core is composed of ARHGAP17, AMOT, MPP5/PALS1, INADL/PATJ and PARD3/PAR3. Heterodimer with MPP1. Interacts with MPP7.
Function:
May play a role in tight junctions biogenesis and in the establishment of cell polarity in epithelial cells. May modulate SC6A1/GAT1-mediated GABA uptake by stabilizing the transporter. Required for localization of EZR to the apical membrane of parietal cells and may play a role in the dynamic remodeling of the apical cytoskeleton.
Subcellular Location:
Cell membrane
Peripheral membrane protein
Endomembrane system
Peripheral membrane protein
Cell junction
tight junction
Localized to the tight junctions of epithelial cells and a subset of intracellular vesicles. In the retina, detected at the outer limiting membrane (OLM), apical to the adherens junction (AJ), where it colocalizes with CRB1. Colocalizes with MPP1 in the retina at the outer limiting membrane (OLM). Localized to the Purkinje cell body and axon.
Protein Attributes:
50:
MTTSHMNGHV | TEESDSEVKN | VDLASPEEHQ | KHREMAVDCP | GDLGTRMMPI |
100:
RRSAQLERIR | QQQEDMRRRR | EEEGKKQELD | LNSSMRLKKL | AQIPPKTGID |
150:
NPMFDTEEGI | VLESPHYAVK | ILEIEDLFSS | LKHIQHTLVD | SQSQEDISLL |
200:
LQLVQNKDFQ | NAFKIHNAIT | VHMNKASPPF | PLISNAQDLA | QEVQTVLKPV |
250:
HHKEGQELTA | LLNTPHIQAL | LLAHDKVAEQ | EMQLEPITDE | RVYESIGQYG |
300:
GETVKIVRIE | KARDIPLGAT | VRNEMDSVII | SRIVKGGAAE | KSGLLHEGDE |
350:
VLEINGIEIR | GKDVNEVFDL | LSDMHGTLTF | VLIPSQQIKP | PPAKETVIHV |
400:
KAHFDYDPSD | DPYVPCRELG | LSFQKGDILH | VISQEDPNWW | QAYREGDEDN |
450:
QPLAGLVPGK | SFQQQREAMK | QTIEEDKEPE | KSGKLWCAKK | NKKKRKKVLY |
500:
NANKNDDYDN | EEILTYEEMS | LYHQPANRKR | PIILIGPQNC | GQNELRQRLM |
550:
NKEKDRFASA | VPHTTRSRRD | QEVAGRDYHF | VSRQAFEADI | AAGKFIEHGE |
600:
FEKNLYGTSI | DSVRQVINSG | KICLLSLRTQ | SLKTLRNSDL | KPYIIFIAPP |
650:
SQERLRALLA | KEGKNPKPEE | LREIIEKTRE | MEQNNGHYFD | TAIVNSDLDK |
675:
AYQELLRLIN | KLDTEPQWVP | STWLR
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human MAGUK p55 subfamily member 5
ELISA Kit for Human MAGUK p55 subfamily member 5
CLIA Kit for Human MAGUK p55 subfamily member 5
CLIA Kit for Human MAGUK p55 subfamily member 5
Polyclonal Antibody for Human MAGUK p55 subfamily member 5
Polyclonal Antibody for Human MAGUK p55 subfamily member 5
Monoclonal Antibody for Human MAGUK p55 subfamily member 5
Monoclonal Antibody for Human MAGUK p55 subfamily member 5
Protein for Human MAGUK p55 subfamily member 5
Protein for Human MAGUK p55 subfamily member 5
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-441 (ISOFORM 1);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 155-675
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Brain .
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