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Index > Protein center > MPP5(Gene name) > Human
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  • MPP5 (Gene name),
  • MAGUK p55 subfamily member 5 (Protein name ),  MPP5_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    MPP5;
    Protein name:
    MAGUK p55 subfamily member 5;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with CRB3, LIN7C and MPDZ. Interacts with INADL, PARD6B, SC6A1 and EZR (By similarity). Forms a complex with CRB1 and MPP4. Component of a complex whose core is composed of ARHGAP17, AMOT, MPP5/PALS1, INADL/PATJ and PARD3/PAR3. Heterodimer with MPP1. Interacts with MPP7.
    Function:
    May play a role in tight junctions biogenesis and in the establishment of cell polarity in epithelial cells. May modulate SC6A1/GAT1-mediated GABA uptake by stabilizing the transporter. Required for localization of EZR to the apical membrane of parietal cells and may play a role in the dynamic remodeling of the apical cytoskeleton.
    Subcellular Location:
    Cell membrane Peripheral membrane protein Endomembrane system Peripheral membrane protein Cell junction tight junction Localized to the tight junctions of epithelial cells and a subset of intracellular vesicles. In the retina, detected at the outer limiting membrane (OLM), apical to the adherens junction (AJ), where it colocalizes with CRB1. Colocalizes with MPP1 in the retina at the outer limiting membrane (OLM). Localized to the Purkinje cell body and axon.
    Protein Attributes:
    Sequence length:
    675
    Sequence:
    50:
    MTTSHMNGHV | TEESDSEVKN | VDLASPEEHQ | KHREMAVDCP | GDLGTRMMPI | 
    100:
    RRSAQLERIR | QQQEDMRRRR | EEEGKKQELD | LNSSMRLKKL | AQIPPKTGID | 
    150:
    NPMFDTEEGI | VLESPHYAVK | ILEIEDLFSS | LKHIQHTLVD | SQSQEDISLL | 
    200:
    LQLVQNKDFQ | NAFKIHNAIT | VHMNKASPPF | PLISNAQDLA | QEVQTVLKPV | 
    250:
    HHKEGQELTA | LLNTPHIQAL | LLAHDKVAEQ | EMQLEPITDE | RVYESIGQYG | 
    300:
    GETVKIVRIE | KARDIPLGAT | VRNEMDSVII | SRIVKGGAAE | KSGLLHEGDE | 
    350:
    VLEINGIEIR | GKDVNEVFDL | LSDMHGTLTF | VLIPSQQIKP | PPAKETVIHV | 
    400:
    KAHFDYDPSD | DPYVPCRELG | LSFQKGDILH | VISQEDPNWW | QAYREGDEDN | 
    450:
    QPLAGLVPGK | SFQQQREAMK | QTIEEDKEPE | KSGKLWCAKK | NKKKRKKVLY | 
    500:
    NANKNDDYDN | EEILTYEEMS | LYHQPANRKR | PIILIGPQNC | GQNELRQRLM | 
    550:
    NKEKDRFASA | VPHTTRSRRD | QEVAGRDYHF | VSRQAFEADI | AAGKFIEHGE | 
    600:
    FEKNLYGTSI | DSVRQVINSG | KICLLSLRTQ | SLKTLRNSDL | KPYIIFIAPP | 
    650:
    SQERLRALLA | KEGKNPKPEE | LREIIEKTRE | MEQNNGHYFD | TAIVNSDLDK | 
    675:
    AYQELLRLIN | KLDTEPQWVP | STWLR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    MIM:
    UniGene:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human MAGUK p55 subfamily member 5
    ELISA Kit for Human MAGUK p55 subfamily member 5
    CLIA Kit for Human MAGUK p55 subfamily member 5
    CLIA Kit for Human MAGUK p55 subfamily member 5
    Polyclonal Antibody for Human MAGUK p55 subfamily member 5
    Polyclonal Antibody for Human MAGUK p55 subfamily member 5
    Monoclonal Antibody for Human MAGUK p55 subfamily member 5
    Monoclonal Antibody for Human MAGUK p55 subfamily member 5
    Protein for Human MAGUK p55 subfamily member 5
    Protein for Human MAGUK p55 subfamily member 5

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Skeletal muscle.
      tissue: Spinal cord.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Eye.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-441 (ISOFORM 1);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 155-675
      tissue: Brain.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: COMPLEX FORMATION WITH CRB1 AND MPP4;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    6. 6.
      "Membrane-associated guanylate kinase proteins MPP4 and MPP5 associate with Veli3 at distinct intercellular junctions of the neurosensory retina."
      Stoehr H. , Molday L.L. , Molday R.S. , Weber B.H.F. , Biedermann B. , Reichenbach A. , Kraemer F.
      J. Comp. Neurol.481:31-41(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    7. 7.
      "A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells."
      Wells C.D. , Fawcett J.P. , Traweger A. , Yamanaka Y. , Goudreault M. , Elder K. , Kulkarni S. , Gish G. , Virag C. , Lim C. , Colwill K. , Starostine A. , Metalnikov P. , Pawson T.
      Cell125:535-548(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;IDENTIFICATION IN A COMPLEX WITH ARHGAP17; AMOT; INADL AND PARD3;INTERACTION WITH MPP7
    8. 8.
      "The MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formation."
      Stucke V.M. , Timmerman E. , Vandekerckhove J. , Gevaert K. , Hall A.
      Mol. Biol. Cell18:1744-1755(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MPP7
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-25;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 11.
      "A unified assembly mode revealed by the structures of tetrameric L27 domain complexes formed by mLin-2/mLin-7 and Patj/Pals1 scaffold proteins."
      Feng W. , Long J.-F. , Zhang M.
      Proc. Natl. Acad. Sci. U.S.A.102:6861-6866(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 118-177;INTERACTION WITH MPDZ
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MPP1;SUBCELLULAR LOCATION
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