Mrc2 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comMrc2 ELISA Kit for Rat(Rattus norvegicus)

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Mrc2 (Gene name),

C-type mannose receptor 2 (Protein name ), MRC2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Mrc2(Endo180);

Protein name:

C-type mannose receptor 2;

Alternative:

Macrophage mannose receptor 2;Endocytic receptor 180;

CD:

CD280;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts directly with PLAUR/UPAR and PLAU/pro-UPA to form a tri-molecular complex. Interacts with collagen V (By similarity). Interacts with C-terminal region of type I collagen/COL1A1.

Function:

May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices (By similarity). May participate in remodeling of extracellular matrix co-operating with the matrix metalloproteinases (MMPs) secreted by hepatic stellate cells. May mediate endocytosis of partially degraded collagens and glycoproteins produced in the extracellular matrix by MMPs.

Subcellular Location:

Cell membrane Single-pass membrane protein

Protein Attributes:

Sequence length:

1480

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1480:

RYSRSSRSGP | AEATEKNILV | SDMEMNEQQE |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q4TU93

STRING:

10116.ENSRNOP00000052010

UniGene:

Rn.213511

KEGG:

rno:498011

Pfam:

PF00040

Uniprot:

Q4TU93

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ELISA Kit for Rat C-type mannose receptor 2

Cat.:

E2105h

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Manual:

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Packing:

96T

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ELISA Kit for Rat C-type mannose receptor 2

Cat.:

E2105m

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MSDS:

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Packing:

96T

ELISA Kit for Rat C-type mannose receptor 2

Cat.:

E2105r

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Packing:

96T

CLIA Kit for Rat C-type mannose receptor 2

Cat.:

U2105r

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat C-type mannose receptor 2

Cat.:

U2105m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat C-type mannose receptor 2

Cat.:

U2105h

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat C-type mannose receptor 2

Cat.:

P2105Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat C-type mannose receptor 2

Cat.:

P2105Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat C-type mannose receptor 2

Cat.:

P2105Rb-r

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat C-type mannose receptor 2

Protein for Rat C-type mannose receptor 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Endo180 binds to the C-terminal region of type I collagen."
Thomas E.K. , Nakamura M. , Wienke D. , Isacke C.M. , Pozzi A. , Liang P.
J. Biol. Chem.280:22596-22605(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];IDENTIFICATION BY MASS SPECTROMETRY;GLYCOSYLATION;INTERACTION WITH COL1A1
strain: Sprague-Dawley.
2.

"Uptake of denatured collagen into hepatic stellate cells: evidence for the involvement of urokinase plasminogen activator receptor-associated protein/Endo180."
Mousavi S.A. , Sato M. , Sporstol M. , Smedsrod B. , Berg T. , Kojima N. , Senoo H.
Biochem. J.387:39-46(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

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