MRGPRD ELISA Kit for Human(Homo sapiens) | EIAab.comMRGPRD ELISA Kit for Human(Homo sapiens)

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Index > Protein center > MRGPRD(Gene name) > Human

MRGPRD (Gene name),

Mas-related G-protein coupled receptor member D (Protein name ), MRGRD_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

MRGPRD(MRGD);

Protein name:

Mas-related G-protein coupled receptor member D;

Alternative:

G-protein coupled receptor TGR7;Beta-alanine receptor;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).

Subcellular Location:

Cell membrane Multi-pass membrane protein Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.

Protein Attributes:

Sequence length:

321

Sequence:

50:

100:

150:

200:

250:

300:

321:

REEPELEGGE | TPTVGTNEMG | A

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

607231

STRING:

9606.ENSP00000310631

Pfam:

PF00001

SMR:

Q8TDS7

KEGG:

hsa:116512

UniGene:

Hs.527802

String:

Q8TDS7

Uniprot:

Q8TDS7

FOR

ELISA Kit for Human Mas-related G-protein coupled receptor member D

CLIA Kit for Human Mas-related G-protein coupled receptor member D

Polyclonal Antibody for Human Mas-related G-protein coupled receptor member D

Monoclonal Antibody for Human Mas-related G-protein coupled receptor member D

Protein for Human Mas-related G-protein coupled receptor member D

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family."
Zylka M.J. , Dong X. , Southwell A.L. , Anderson D.J.
Proc. Natl. Acad. Sci. U.S.A.100:10043-10048(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Identification of a G protein-coupled receptor specifically responsive to beta-alanine."
Shinohara T. , Harada M. , Ogi K. , Maruyama M. , Fujii R. , Tanaka H. , Fukusumi S. , Komatsu H. , Hosoya M. , Noguchi Y. , Watanabe T. , Moriya T. , Itoh Y. , Hinuma S.
J. Biol. Chem.279:23559-23564(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;POSSIBLE FUNCTION
tissue: Liver.
3.

"Identification of G protein-coupled receptor genes from the human genome sequence."
Takeda S. , Kadowaki S. , Haga T. , Takaesu H. , Mitaku S.
FEBS Lett.520:97-101(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"Genome-wide discovery and analysis of human seven transmembrane helix receptor genes."
Suwa M. , Sato T. , Okouchi I. , Arita M. , Futami K. , Matsumoto S. , Tsutsumi S. , Aburatani H. , Asai K. , Akiyama Y.
Submitted (2001-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]

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