MRGPRX2 ELISA Kit for Human(Homo sapiens) | EIAab.comMRGPRX2 ELISA Kit for Human(Homo sapiens)

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MRGPRX2 (Gene name),

Mas-related G-protein coupled receptor member X2 (Protein name ), MRGX2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

MRGPRX2(MRGX2);

Protein name:

Mas-related G-protein coupled receptor member X2;

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled.

Subcellular Location:

Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

330

Sequence:

50:

100:

150:

200:

250:

300:

330:

QRALQDIAEV | DHSEGCFRQG | TPEMSRSSLV |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00001

String:

Q96LB1

SMR:

Q96LB1

MIM:

607228

UniGene:

Hs.350566

KEGG:

hsa:117194

Uniprot:

Q96LB1

FOR

ELISA Kit for Human Mas-related G-protein coupled receptor member X2

CLIA Kit for Human Mas-related G-protein coupled receptor member X2

Polyclonal Antibody for Human Mas-related G-protein coupled receptor member X2

Monoclonal Antibody for Human Mas-related G-protein coupled receptor member X2

Protein for Human Mas-related G-protein coupled receptor member X2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons."
Dong X. , Han S.-K. , Zylka M.J. , Simon M.I. , Anderson D.J.
Cell106:619-632(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"Identification of G protein-coupled receptor genes from the human genome sequence."
Takeda S. , Kadowaki S. , Haga T. , Takaesu H. , Mitaku S.
FEBS Lett.520:97-101(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.

"Genome-wide discovery and analysis of human seven transmembrane helix receptor genes."
Suwa M. , Sato T. , Okouchi I. , Arita M. , Futami K. , Matsumoto S. , Tsutsumi S. , Aburatani H. , Asai K. , Akiyama Y.
Submitted (2001-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"Adaptive evolution of MRGX2, a human sensory neuron specific gene involved in nociception."
Yang S. , Liu Y. , Lin A.A. , Cavalli-Sforza L.L. , Zhao Z. , Su B.
Gene352:30-35(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS HIS-16; SER-62 AND LEU-78
5.

"Isolation of genomic DNA coding for human MAS-related GPR, member X2 (MRGPRX2)."
Martin A.L. , Kaighin V.A. , Aronstam R.S.
Submitted (2008-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT SER-62
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
7.

"MrgX2 is a high potency cortistatin receptor expressed in dorsal root ganglion."
Robas N. , Mead E. , Fidock M.
J. Biol. Chem.278:44400-44404(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;POSSIBLE FUNCTION

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