Gene name:
Abcc3 (Cmoat2;Mrp3) ;
Protein name:
Canalicular multispecific organic anion transporter 2 ;
Alternative:
Multidrug resistance-associated protein 3 ;ATP-binding cassette sub-family C member 3 ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes.
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MDRLCGSGEL | GSKFWDSNLS | IYTNTPDLTP | CFQNSLLAWV | PCIYLWAALP |
100:
CYLFYLRHHQ | LGYIVLSWLS | RLKTALGVLL | WCVSWVDLFY | SFHGLIHGSS |
150:
PAPVFFVTPL | VVGITMLLAT | LLIQYERLRG | VQSSGVLIIF | WLLCVICAII |
200:
PFRSKILSAL | AEGKILDPFR | FTTFYIYFAL | VFCALILSCF | KEKPPLFSPE |
250:
NLDTNPCPEA | SAGFFSRLSF | WWFTRLAILG | YRRPLEDRDL | WSLSEEDCSH |
300:
KVVQRLLEAW | QKQQNQASGS | QTATAEPKIP | GEDAVLLKPR | PKSKQPSFLR |
350:
ALVRTFTSSL | LMSACFNLIQ | NLLGFVNPQL | LSILIRFISD | PTAPTWWGFL |
400:
LAGLMFLSST | MQTLILHQYY | HCIFVMALRL | RTAIIGVIYR | KALVITNSVK |
450:
RESTVGEMVN | LMSVDAQRFM | DVSPFINLLW | SAPLQVILAI | YFLWQILGPS |
500:
ALAGVAVIVL | LIPLNGAVSM | KMKTYQVKQM | KFKDSRIKLM | SEILNGIKVL |
550:
KLYAWEPSFL | EQVKGIRQSE | LQLLRKGAYL | QAISTFIWIC | TPFLVTLITL |
600:
GVYVYVDESN | VLDAEKAFVS | LSLFNILKIP | LNMLPQLISG | LTQASVSLKR |
650:
IQDFLNQNEL | DPQCVERKTI | SPGYAITIHN | GTFTWAQDLP | PTLHSLNIQI |
700:
PKGALVAVVG | PVGCGKSSLV | SALLGEMEKL | EGVVSVKGSV | AYVPQQAWIQ |
750:
NCTLQENVLF | GQPMNPKRYQ | QALETCALLA | DLDVLPGGDQ | TEIGEKGINL |
800:
SGGQRQRVSL | ARAVYSDANI | FLLDDPLSAV | DSHVAKHIFD | QVIGPEGVLA |
850:
GKTRVLVTHG | ISFLPQTDFI | IVLAGGQVSE | MGHYSALLQH | DGSFANFLRN |
900:
YAPDEDQEDH | EAALQNANEE | VLLLEDTLST | HTDLTDNEPA | IYEVRKQFMR |
950:
EMSSLSSEGE | VQNRTMPKKH | TNSLEKEALV | TKTKETGALI | KEEIAETGNV |
1000:
KLSVYWDYAK | SMGLCTTLSI | CLLYGGQSAA | AIGANVWLSA | WSNDAEEHGQ |
1050:
QNKTSVRLGV | YAALGILQGL | LVMLSAFTMV | VGAIQAARLL | HEALLHNKIR |
1100:
SPQSFFDTTP | SGRILNRFSK | DIYVIDEVLA | PTILMLLNSF | FTSISTIMVI |
1150:
VASTPLFMVV | VLPLAVLYGF | VQRFYVATSR | QLKRLESISR | SPIFSHFSET |
1200:
VTGTSVIRAY | GRIQDFKVLS | DTKVDNNQKS | SYPYIASNRW | LGVHVEFVGN |
1250:
CVVLFAALFA | VIGRNSLNPG | LVGLSVSYAL | QVTMALNWMI | RMISDLESNI |
1300:
IAVERVKEYS | KTKTEAPWVV | ESNRAPEGWP | TRGMVEFRNY | SVRYRPGLEL |
1350:
VLKNVTVHVQ | GGEKVGIVGR | TGAGKSSMTL | CLFRILEAAE | GEIVIDGLNV |
1400:
AHIGLHDLRS | QLTIIPQDPI | LFSGTLRMNL | DPFGRYSEED | IWRALELSHL |
1450:
NTFVSSQPAG | LDFQCAEGGD | NLSVGQRQLV | CLARALLRKS | RVLVLDEATA |
1500:
AIDLETDDLI | QGTIRTQFED | CTVLTIAHRL | NTIMDYNRVL | VLDKGVVAEF |
1523:
DSPVNLIAAG | GIFYGMAKDA | GLA
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
ELISA Kit for Mouse Canalicular multispecific organic anion transporter 2
ELISA Kit for Mouse Canalicular multispecific organic anion transporter 2
ELISA Kit for Mouse Canalicular multispecific organic anion transporter 2
CLIA Kit for Mouse Canalicular multispecific organic anion transporter 2
CLIA Kit for Mouse Canalicular multispecific organic anion transporter 2
CLIA Kit for Mouse Canalicular multispecific organic anion transporter 2
Polyclonal Antibody for Mouse Canalicular multispecific organic anion transporter 2
Polyclonal Antibody for Mouse Canalicular multispecific organic anion transporter 2
Polyclonal Antibody for Mouse Canalicular multispecific organic anion transporter 2
Monoclonal Antibody for Mouse Canalicular multispecific organic anion transporter 2
Monoclonal Antibody for Mouse Canalicular multispecific organic anion transporter 2
Monoclonal Antibody for Mouse Canalicular multispecific organic anion transporter 2
Protein for Mouse Canalicular multispecific organic anion transporter 2
Protein for Mouse Canalicular multispecific organic anion transporter 2
Protein for Mouse Canalicular multispecific organic anion transporter 2
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
"Analysis of the in vivo functions of Mrp3."
Belinsky M.G.
,
Dawson P.A.
,
Shchaveleva I.
,
Bain L.J.
,
Wang R.
,
Ling V.
,
Chen Z.-S.
,
Grinberg A.
,
Westphal H.
,
Klein-Szanto A.
,
Lerro A.
,
Kruh G.D.
Mol. Pharmacol.68:160-168(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 3)
strain :
BALB/c .
tissue :
Liver .
3.
"The transcriptional landscape of the mammalian genome."
Carninci P.
,
Kasukawa T.
,
Katayama S.
,
Gough J.
,
Frith M.C.
,
Maeda N.
,
Oyama R.
,
Ravasi T.
,
Lenhard B.
,
Wells C.
,
Kodzius R.
,
Shimokawa K.
,
Bajic V.B.
,
Brenner S.E.
,
Batalov S.
,
Forrest A.R.
,
Zavolan M.
,
Davis M.J.
,
Wilming L.G.
,
Aidinis V.
,
Allen J.E.
,
Ambesi-Impiombato A.
,
Apweiler R.
,
Aturaliya R.N.
,
Bailey T.L.
,
Bansal M.
,
Baxter L.
,
Beisel K.W.
,
Bersano T.
,
Bono H.
,
Chalk A.M.
,
Chiu K.P.
,
Choudhary V.
,
Christoffels A.
,
Clutterbuck D.R.
,
Crowe M.L.
,
Dalla E.
,
Dalrymple B.P.
,
de Bono B.
,
Della Gatta G.
,
di Bernardo D.
,
Down T.
,
Engstrom P.
,
Fagiolini M.
,
Faulkner G.
,
Fletcher C.F.
,
Fukushima T.
,
Furuno M.
,
Futaki S.
,
Gariboldi M.
,
Georgii-Hemming P.
,
Gingeras T.R.
,
Gojobori T.
,
Green R.E.
,
Gustincich S.
,
Harbers M.
,
Hayashi Y.
,
Hensch T.K.
,
Hirokawa N.
,
Hill D.
,
Huminiecki L.
,
Iacono M.
,
Ikeo K.
,
Iwama A.
,
Ishikawa T.
,
Jakt M.
,
Kanapin A.
,
Katoh M.
,
Kawasawa Y.
,
Kelso J.
,
Kitamura H.
,
Kitano H.
,
Kollias G.
,
Krishnan S.P.
,
Kruger A.
,
Kummerfeld S.K.
,
Kurochkin I.V.
,
Lareau L.F.
,
Lazarevic D.
,
Lipovich L.
,
Liu J.
,
Liuni S.
,
McWilliam S.
,
Madan Babu M.
,
Madera M.
,
Marchionni L.
,
Matsuda H.
,
Matsuzawa S.
,
Miki H.
,
Mignone F.
,
Miyake S.
,
Morris K.
,
Mottagui-Tabar S.
,
Mulder N.
,
Nakano N.
,
Nakauchi H.
,
Ng P.
,
Nilsson R.
,
Nishiguchi S.
,
Nishikawa S.
,
Nori F.
,
Ohara O.
,
Okazaki Y.
,
Orlando V.
,
Pang K.C.
,
Pavan W.J.
,
Pavesi G.
,
Pesole G.
,
Petrovsky N.
,
Piazza S.
,
Reed J.
,
Reid J.F.
,
Ring B.Z.
,
Ringwald M.
,
Rost B.
,
Ruan Y.
,
Salzberg S.L.
,
Sandelin A.
,
Schneider C.
,
Schoenbach C.
,
Sekiguchi K.
,
Semple C.A.
,
Seno S.
,
Sessa L.
,
Sheng Y.
,
Shibata Y.
,
Shimada H.
,
Shimada K.
,
Silva D.
,
Sinclair B.
,
Sperling S.
,
Stupka E.
,
Sugiura K.
,
Sultana R.
,
Takenaka Y.
,
Taki K.
,
Tammoja K.
,
Tan S.L.
,
Tang S.
,
Taylor M.S.
,
Tegner J.
,
Teichmann S.A.
,
Ueda H.R.
,
van Nimwegen E.
,
Verardo R.
,
Wei C.L.
,
Yagi K.
,
Yamanishi H.
,
Zabarovsky E.
,
Zhu S.
,
Zimmer A.
,
Hide W.
,
Bult C.
,
Grimmond S.M.
,
Teasdale R.D.
,
Liu E.T.
,
Brusic V.
,
Quackenbush J.
,
Wahlestedt C.
,
Mattick J.S.
,
Hume D.A.
,
Kai C.
,
Sasaki D.
,
Tomaru Y.
,
Fukuda S.
,
Kanamori-Katayama M.
,
Suzuki M.
,
Aoki J.
,
Arakawa T.
,
Iida J.
,
Imamura K.
,
Itoh M.
,
Kato T.
,
Kawaji H.
,
Kawagashira N.
,
Kawashima T.
,
Kojima M.
,
Kondo S.
,
Konno H.
,
Nakano K.
,
Ninomiya N.
,
Nishio T.
,
Okada M.
,
Plessy C.
,
Shibata K.
,
Shiraki T.
,
Suzuki S.
,
Tagami M.
,
Waki K.
,
Watahiki A.
,
Okamura-Oho Y.
,
Suzuki H.
,
Kawai J.
,
Hayashizaki Y.
more...
Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
strain :
C57BL/6J .
tissue :
Liver .
4.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
,
Goodstadt L.
,
Hillier L.W.
,
Zody M.C.
,
Goldstein S.
,
She X.
,
Bult C.J.
,
Agarwala R.
,
Cherry J.L.
,
DiCuccio M.
,
Hlavina W.
,
Kapustin Y.
,
Meric P.
,
Maglott D.
,
Birtle Z.
,
Marques A.C.
,
Graves T.
,
Zhou S.
,
Teague B.
,
Potamousis K.
,
Churas C.
,
Place M.
,
Herschleb J.
,
Runnheim R.
,
Forrest D.
,
Amos-Landgraf J.
,
Schwartz D.C.
,
Cheng Z.
,
Lindblad-Toh K.
,
Eichler E.E.
,
Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 4-1523 (ISOFORM 2)
strain :
FVB/N .
tissue :
Brain .
tissue :
Liver .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .