Gene name:
Abcc3 (Cmoat2;Mlp2;Mrp3) ;
Protein name:
Canalicular multispecific organic anion transporter 2 ;
Alternative:
MRP-like protein 2 (MLP-2) ;ATP-binding cassette sub-family C member 3 ;Multidrug resistance-associated protein 3 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes.
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MDRLCGSGEL | GSKFWDSNLT | VYTNTPDLTP | CFQNSLLAWV | PCIYLWAALP |
100:
CYLFYLRHHR | LGYIVLSCLS | RLKTALGVLL | WCISWVDLFY | SFHGLVHGSS |
150:
PAPVFFITPL | LVGITMLLAT | LLIQYERLRG | VRSSGVLIIF | WLLCVICAII |
200:
PFRSKILLAL | AEGKILDPFR | FTTFYIYFAL | VLCAFILSCF | QEKPPLFSPE |
250:
NLDTNPCPEA | SAGFFSRLSF | WWFTKLAILG | YRRPLEDSDL | WSLSEEDCSH |
300:
KVVQRLLEAW | QKQQTQASGP | QTAALEPKIA | GEDEVLLKAR | PKTKKPSFLR |
350:
ALVRTFTSSL | LMGACFKLIQ | DLSPSSTHSC | SASSSGLFRP | HGPYWWGFLL |
400:
AGLMFVSSTM | QTLILHQHYH | CIFVMALRIR | TAIIGVIYRK | ALTITNSVKR |
450:
EYTVGEMVNL | MSVDAQRFMD | VSPFINLLWS | APLQVILAIY | FLWQILGPSA |
500:
LAGVAVIVLL | IPLNGAVSMK | MKTYQVQQMK | FKDSRIKLMS | EILNGIKVLK |
550:
LYAWEPTFLE | QVEGIRQGEL | QLLRKGAYLQ | AISTFIWVCT | PFMVTLITLG |
600:
VYVCVDKNNV | LDAEKAFVSL | SLFNILKIPL | NLLPQLISGM | TQTSVSLKRI |
650:
QDFLNQDELD | PQCVERKTIS | PGRAITIHNG | TFSWSKDLPP | TLHSINIQIP |
700:
KGALVAVVGP | VGCGKSSLVS | ALLGEMEKLE | GAVSVKGSVA | YVPQQAWIQN |
750:
CTLQENVLFG | QPMNPKRYQQ | ALETCALLAD | LDVLPGGDQT | EIGEKGINLS |
800:
GGQRQRVSLA | RAVYSDANIF | LLDDPLSAVD | SHVAKHIFDQ | VIGPEGVLAG |
850:
KTRVLVTHGI | SFLPQTDFII | VLADGQITEM | GHYSELLQHD | GSFANFLRNY |
900:
APDENQEANE | GVLQHANEEV | LLLEDTLSTH | TDLTDTEPAI | YEVRKQFMRE |
950:
MSSLSSEGEG | QNRPVLKRYT | SSLEKEVPAT | QTKETGALIK | EEIAETGNVK |
1000:
LSVYWDYAKS | VGLCTTLFIC | LLYAGQNAVA | IGANVWLSAW | TNDVEEHGQQ |
1050:
NNTSVRLGVY | ATLGILQGLL | VMLSAFTMVV | GAIQAARLLH | TALLHNQIRA |
1100:
PQSFFDTTPS | GRILNRFSKD | IYVIHEVLAP | TILMLFNSFY | TSISTIVVIV |
1150:
ASTPLFCVVV | LPLAVFYGFV | QRFYVATSRQ | LKRLESVSRS | PIFSHFSETV |
1200:
TGTSVIRAYG | RVQDFKVLSD | AKVDSNQKTT | YPYIASNRWL | GVHVEFVGNC |
1250:
VVLFSALFAV | IGRNSLNPGL | VGLSVSYALQ | VTLSLNWMIR | TLSDLESNII |
1300:
AVERVKEYSK | TETEAPWVLE | SNRAPEGWPR | SGVVEFRNYS | VRYRPGLELV |
1350:
LKNLTLHVQG | GEKVGIVGRT | GAGKSSMTLC | LFRILEAAEG | EIFIDGLNVA |
1400:
HIGLHDLRSQ | LTIIPQDPIL | FSGTLRMNLD | PFGRYSDEDI | WRTLELSHLS |
1450:
AFVSSQPTGL | DFQCSEGGDN | LSVGQRQLVC | LARALLRKSR | VLVLDEATAA |
1500:
IDLETDDLIQ | GTIRTQFEDC | TVLTIAHRLN | TIMDYNRVLV | LDKGVVAEFD |
1522:
SPVNLIAAGG | IFYGMAKDAG | LA
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rat
ELISA Kit for Rat Canalicular multispecific organic anion transporter 2
ELISA Kit for Rat Canalicular multispecific organic anion transporter 2
ELISA Kit for Rat Canalicular multispecific organic anion transporter 2
CLIA Kit for Rat Canalicular multispecific organic anion transporter 2
CLIA Kit for Rat Canalicular multispecific organic anion transporter 2
CLIA Kit for Rat Canalicular multispecific organic anion transporter 2
Polyclonal Antibody for Rat Canalicular multispecific organic anion transporter 2
Polyclonal Antibody for Rat Canalicular multispecific organic anion transporter 2
Polyclonal Antibody for Rat Canalicular multispecific organic anion transporter 2
Monoclonal Antibody for Rat Canalicular multispecific organic anion transporter 2
Monoclonal Antibody for Rat Canalicular multispecific organic anion transporter 2
Monoclonal Antibody for Rat Canalicular multispecific organic anion transporter 2
Protein for Rat Canalicular multispecific organic anion transporter 2
Protein for Rat Canalicular multispecific organic anion transporter 2
Protein for Rat Canalicular multispecific organic anion transporter 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Liver .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Sprague-Dawley .
tissue :
Colon .