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Index > Protein center > Msi1(Gene name) > Mouse
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  • Msi1 (Gene name),
  • RNA-binding protein Musashi homolog 1 (Protein name ),  MSI1H_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Msi1(Msi1h);
    Protein name:
    RNA-binding protein Musashi homolog 1(Musashi-1);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U(1-3)AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system.
    Subcellular Location:
    Cytoplasm Nucleus
    Protein Attributes:
    Sequence length:
    362
    Sequence:
    50:
    METDAPQPGL | ASPDSPHDPC | KMFIGGLSWQ | TTQEGLREYF | GQFGEVKECL | 
    100:
    VMRDPLTKRS | RGFGFVTFMD | QAGVDKVLAQ | SRHELDSKTI | DPKVAFPRRA | 
    150:
    QPKMVTRTKK | IFVGGLSVNT | TVEDVKHYFE | QFGKVDDAML | MFDKTTNRHR | 
    200:
    GFGFVTFESE | DIVEKVCEIH | FHEINNKMVE | CKKAQPKEVM | SPTGSARGRS | 
    250:
    RVMPYGMDAF | MLGIGMLGYP | GFQATTYASR | SYTGLAPGYT | YQFPEFRVER | 
    300:
    SPLPSAPVLP | ELTAIPLTAY | GPMAAAAAAA | AVVRGTGSHP | WTMAPPPGST | 
    350:
    PSRTGGFLGT | TSPGPMAELY | GAANQDSGVS | SYISAASPAP | STGFGHSLGG | 
    362:
    PLIATAFTNG | YH
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    KEGG:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Musashi-1
    ELISA Kit for Mouse Musashi-1
    ELISA Kit for Mouse Musashi-1
    CLIA Kit for Mouse Musashi-1
    CLIA Kit for Mouse Musashi-1
    CLIA Kit for Mouse Musashi-1
    Polyclonal Antibody for Mouse Musashi-1
    Polyclonal Antibody for Mouse Musashi-1
    Polyclonal Antibody for Mouse Musashi-1
    Monoclonal Antibody for Mouse Musashi-1
    Monoclonal Antibody for Mouse Musashi-1
    Monoclonal Antibody for Mouse Musashi-1
    Protein for Mouse Musashi-1
    Protein for Mouse Musashi-1
    Protein for Mouse Musashi-1

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    References
    1. 1.
      "Mouse-Musashi-1, a neural RNA-binding protein highly enriched in the mammalian CNS stem cell."
      Sakakibara S. , Imai T. , Hamaguchi K. , Okabe M. , Aruga J. , Nakajima K. , Yasutomi D. , Nagata T. , Kurihara Y. , Uesugi S. , Miyata T. , Ogawa M. , Mikoshiba K. , Okano H.
      Dev. Biol.176:230-242(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);RNA-BINDING;TISSUE SPECIFICITY
      strain: ICR.
      tissue: Cerebellum.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: C57BL/6J.
      tissue: Spinal ganglion.
    3. 3.
      "The neural RNA-binding protein Musashi1 translationally regulates mammalian numb gene expression by interacting with its mRNA."
      Imai T. , Tokunaga A. , Yoshida T. , Hashimoto M. , Mikoshiba K. , Weinmaster G. , Nakafuku M. , Okano H.
      Mol. Cell. Biol.21:3888-3900(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF PHE-63; PHE-65 AND PHE-68
    4. 4.
      "RNA-binding protein Musashi family: roles for CNS stem cells and a subpopulation of ependymal cells revealed by targeted disruption and antisense ablation."
      Sakakibara S. , Nakamura Y. , Yoshida T. , Shibata S. , Koike M. , Takano H. , Ueda S. , Uchiyama Y. , Noda T. , Okano H.
      Proc. Natl. Acad. Sci. U.S.A.99:15194-15199(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    5. 5.
      "Structure, backbone dynamics and interactions with RNA of the C-terminal RNA-binding domain of a mouse neural RNA-binding protein, Musashi1."
      Nagata T. , Kanno R. , Kurihara Y. , Uesugi S. , Imai T. , Sakakibara S. , Okano H. , Katahira M.
      J. Mol. Biol.287:315-330(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 110-184;INTERACTION WITH RNA
    6. 6.
      "Origin of higher affinity to RNA of the N-terminal RNA-binding domain than that of the C-terminal one of a mouse neural protein, musashi1, as revealed by comparison of their structures, modes of interaction, surface electrostatic potentials, and backbone dynamics."
      Miyanoiri Y. , Kobayashi H. , Imai T. , Watanabe M. , Nagata T. , Uesugi S. , Okano H. , Katahira M.
      J. Biol. Chem.278:41309-41315(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 20-96;INTERACTION WITH RNA
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