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Index > Protein center > Msx2(Gene name) > Mouse
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  • Msx2 (Gene name),
  • Homeobox protein MSX-2 (Protein name ),  MSX2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Msx2(Hox-8.1;Msx-2);
    Protein name:
    Homeobox protein MSX-2;
    Alternative:
    Homeobox protein Hox-8-1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with MINT. Interacts with XRCC6 (Ku70) and XRCC5 (Ku80).
    Function:
    Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antogonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    267
    Sequence:
    50:
    MASPTKGGDL | FSSDEEGPAV | LAGPGPGPGG | AEGSAEERRV | KVSSLPFSVE | 
    100:
    ALMSDKKPPK | ESPAVPPDCA | SAGAVLRPLL | LPGHGVRDAH | SPGPLVKPFE | 
    150:
    TASVKSENSE | DGAPWIQEPG | RYSPPPRHMS | PTTCTLRKHK | TNRKPRTPFT | 
    200:
    TSQLLALERK | FRQKQYLSIA | ERAEFSSSLN | LTETQVKIWF | QNRRAKAKRL | 
    250:
    QEAELEKLKM | AAKPMLPSGF | SLPFPINSPL | QAASIYGASY | PFHRPVLPIP | 
    267:
    PVGLYATPVG | YGMYHLS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    String:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Homeobox protein MSX-2
    ELISA Kit for Mouse Homeobox protein MSX-2
    ELISA Kit for Mouse Homeobox protein MSX-2
    ELISA Kit for Mouse Homeobox protein MSX-2
    ELISA Kit for Mouse Homeobox protein MSX-2
    ELISA Kit for Mouse Homeobox protein MSX-2
    CLIA Kit for Mouse Homeobox protein MSX-2
    CLIA Kit for Mouse Homeobox protein MSX-2
    CLIA Kit for Mouse Homeobox protein MSX-2
    CLIA Kit for Mouse Homeobox protein MSX-2
    CLIA Kit for Mouse Homeobox protein MSX-2
    CLIA Kit for Mouse Homeobox protein MSX-2
    Polyclonal Antibody for Mouse Homeobox protein MSX-2
    Polyclonal Antibody for Mouse Homeobox protein MSX-2
    Polyclonal Antibody for Mouse Homeobox protein MSX-2
    Polyclonal Antibody for Mouse Homeobox protein MSX-2
    Polyclonal Antibody for Mouse Homeobox protein MSX-2
    Polyclonal Antibody for Mouse Homeobox protein MSX-2
    Monoclonal Antibody for Mouse Homeobox protein MSX-2
    Monoclonal Antibody for Mouse Homeobox protein MSX-2
    Monoclonal Antibody for Mouse Homeobox protein MSX-2
    Monoclonal Antibody for Mouse Homeobox protein MSX-2
    Monoclonal Antibody for Mouse Homeobox protein MSX-2
    Monoclonal Antibody for Mouse Homeobox protein MSX-2
    Protein for Mouse Homeobox protein MSX-2
    Protein for Mouse Homeobox protein MSX-2
    Protein for Mouse Homeobox protein MSX-2
    Protein for Mouse Homeobox protein MSX-2
    Protein for Mouse Homeobox protein MSX-2
    Protein for Mouse Homeobox protein MSX-2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The Msh-like homeobox genes define domains in the developing vertebrate eye."
      Monaghan A.P. , Davidson D.R. , Sime C. , Graham E. , Baldock R. , Bhattacharya S.S. , Hill R.E.
      Development112:1053-1061(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C57BL/6.
    2. 2.
      "Genomic structure, chromosomal location, and evolution of the mouse Hox 8 gene."
      Bell J.R. , Noveen A. , Liu Y.H. , Ma L. , Dobias S. , Kundu R. , Luo W. , Xia Y.
      Genomics16:123-131(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Cloning and evolutionary analysis of msh-like homeobox genes from mouse, zebrafish and ascidian."
      Holland P.W.H.
      Gene98:253-257(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 142-202
    4. 4.
      "Position-dependent expression of two related homeobox genes in developing vertebrate limbs."
      Davidson D.R. , Crawley A. , Hill R.E. , Tickle C.
      Nature352:429-431(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    5. 5.
      "The RRM domain of MINT, a novel msx2 binding protein, recognizes and regulates the rat osteocalcin promoter."
      Newberry E.P. , Latifi T. , Towler D.A.
      Biochemistry38:10678-10690(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MINT
    6. 6.
      "Bone morphogenetic protein-2-induced alkaline phosphatase expression is stimulated by Dlx5 and repressed by Msx2."
      Kim Y.J. , Lee M.H. , Wozney J.M. , Cho J.Y. , Ryoo H.M.
      J. Biol. Chem.279:50773-50780(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION;DNA-BINDING
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