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Index > Protein center > MTBP(Gene name) > Human
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  • MTBP (Gene name),
  • Mdm2-binding protein (Protein name ),  MTBP_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    MTBP;
    Protein name:
    Mdm2-binding protein(hMTBP);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with MDM2.
    Function:
    Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    904
    Sequence:
    50:
    MDRYLLLVIW | GEGKFPSAAS | REAEHGPEVS | SGEGTENQPD | FTAANVYHLL | 
    100:
    KRSISASINP | EDSTFPACSV | GGIPGSKKWF | FAVQAIYGFY | QFCSSDWQEI | 
    150:
    HFDTEKDKIE | DVLQTNIEEC | LGAVECFEEE | DSNSRESLSL | ADLYEEAAEN | 
    200:
    LHQLSDKLPA | PGRAMVDIIL | LLSDKDPPKL | KDYLPTVGAL | KHLREWYSAK | 
    250:
    ITIAGNHCEI | NCQKIAEYLS | ANVVSLEDLR | NVIDSKELWR | GKIQIWERKF | 
    300:
    GFEISFPEFC | LKGVTLKNFS | TSNLNTDFLA | KKIIPSKDKN | ILPKVFHYYG | 
    350:
    PALEFVQMIK | LSDLPSCYMS | DIEFELGLTN | STKQNSVLLL | EQISSLCSKV | 
    400:
    GALFVLPCTI | SNILIPPPNQ | LSSRKWKEYI | AKKPKTISVP | DVEVKGECSS | 
    450:
    YYLLLQGNGN | RRCKATLIHS | ANQINGSFAL | NLIHGKMKTK | TEEAKLSFPF | 
    500:
    DLLSLPHFSG | EQIVQREKQL | ANVQVLALEE | CLKRRKLAKQ | PETVSVAELK | 
    550:
    SLLVLTRKHF | LDYFDAVIPK | MILRKMDKIK | TFNILNDFSP | VEPNSSSLME | 
    600:
    TNPLEWPERH | VLQNLETFEK | TKQKMRTGSL | PHSSEQLLGH | KEGPRDSITL | 
    650:
    LDAKELLKYF | TSDGLPIGDL | QPLPIQKGEK | TFVLTPELSP | GKLQVLPFEK | 
    700:
    ASVCHYHGIE | YCLDDRKALE | RDGGFSELQS | RLIRYETQTT | CTRESFPVPT | 
    750:
    VLSPLPSPVV | SSDPGSVPDG | EVLQNELRTE | VSRLKRRSKD | LNCLYPRKRL | 
    800:
    VKSESSESLL | SQTTGNSNHY | HHHVTSRKPQ | TERSLPVTCP | LVPIPSCETP | 
    850:
    KLATKTSSGQ | KSMHESKTSR | QIKESRSQKH | TRILKEVVTE | TLKKHSITET | 
    900:
    HECFTACSQR | LFEISKFYLK | DLKTSRGLFE | EMKKTANNNA | VQVIDWVLEK | 
    904:
    TSKK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    MIM:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human hMTBP
    Cat.:
    E1159h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human hMTBP
    Cat.:
    E1159m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human hMTBP
    Cat.:
    U1159h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human hMTBP
    Cat.:
    U1159m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human hMTBP
    Cat.:
    P1159Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human hMTBP
    Cat.:
    P1159Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human hMTBP
    Monoclonal Antibody for Human hMTBP
    Protein for Human hMTBP
    Protein for Human hMTBP

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-141 (ISOFORM 1)
      tissue: Embryo.
    2. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Prostate.
    4. 5.
      "Regulation of p53 and MDM2 activity by MTBP."
      Brady M. , Vlatkovic N. , Boyd M.T.
      Mol. Cell. Biol.25:545-553(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH MDM2
    5. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-639;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    6. 7.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    7. 8.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-703 AND SER-707;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    8. 9.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-639;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
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