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Index > Protein center > MTMR3(Gene name) > Human
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  • MTMR3 (Gene name),
  • Myotubularin-related protein 3 (Protein name ),  MTMR3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    MTMR3(KIAA0371;ZFYVE10);
    Protein name:
    Myotubularin-related protein 3;
    Alternative:
    Zinc finger FYVE domain-containing protein 10;FYVE domain-containing dual specificity protein phosphatase 1(FYVE-DSP1);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. May also dephosphorylate proteins phosphorylated on Ser, Thr, and Tyr residues.
    Subcellular Location:
    Cytoplasm Membrane Peripheral membrane protein
    Protein Attributes:
    Sequence length:
    1198
    Sequence:
    50:
    MDEETRHSLE | CIQANQIFPR | KQLIREDENL | QVPFLELHGE | STEFVGRAED | 
    100:
    AIIALSNYRL | HIKFKESLVN | VPLQLIESVE | CRDIFQLHLT | CKDCKVIRCQ | 
    150:
    FSTFEQCQEW | LKRLNNAIRP | PAKIEDLFSF | AYHAWCMEVY | ASEKEQHGDL | 
    200:
    CRPGEHVTSR | FKNEVERMGF | DMNNAWRISN | INEKYKLCGS | YPQELIVPAW | 
    250:
    ITDKELESVS | SFRSWKRIPA | VIYRHQSNGA | VIARCGQPEV | SWWGWRNADD | 
    300:
    EHLVQSVAKA | CASDSRSSGS | KLSTRNTSRD | FPNGGDLSDV | EFDSSLSNAS | 
    350:
    GAESLAIQPQ | KLLILDARSY | AAAVANRAKG | GGCECPEYYP | NCEVVFMGMA | 
    400:
    NIHSIRRSFQ | SLRLLCTQMP | DPGNWLSALE | STKWLHHLSV | LLKSALLVVH | 
    450:
    AVDQDQRPVL | VHCSDGWDRT | PQIVALAKLL | LDPYYRTIEG | FQVLVEMEWL | 
    500:
    DFGHKFADRC | GHGENSDDLN | ERCPVFLQWL | DCVHQLQRQF | PCSFEFNEAF | 
    550:
    LVKLVQHTYS | CLFGTFLCNN | AKERGEKHTQ | ERTCSVWSLL | RAGNKAFKNL | 
    600:
    LYSSQSEAVL | YPVCHVRNLM | LWSAVYLPCP | SPTTPVDDSC | APYPAPGTSP | 
    650:
    DDPPLSRLPK | TRSYDNLTTA | CDNTVPLASR | RCSDPSLNEK | WQEHRRSLEL | 
    700:
    SSLAGPGEDP | LSADSLGKPT | RVPGGAELSV | AAGVAEGQME | NILQEATKEE | 
    750:
    SGVEEPAHRA | GIEIQEGKED | PLLEKESRRK | TPEASAIGLH | QDPELGDAAL | 
    800:
    RSHLDMSWPL | FSQGISEQQS | GLSVLLSSLQ | VPPRGEDSLE | VPVEQFRIEE | 
    850:
    IAEGREEAVL | PIPVDAKVGY | GTSQSCSLLP | SQVPFETRGP | NVDSSTDMLV | 
    900:
    EDKVKSVSGP | QGHHRSCLVN | SGKDRLPQTM | EPSPSETSLV | ERPQVGSVVH | 
    950:
    RTSLGSTLSL | TRSPCALPLA | ECKEGLVCNG | APETENRASE | QPPGLSTLQM | 
    1000:
    YPTPNGHCAN | GEAGRSKDSL | SRQLSAMSCS | SAHLHSRNLH | HKWLHSHSGR | 
    1050:
    PSATSSPDQP | SRSHLDDDGM | SVYTDTIQQR | LRQIESGHQQ | EVETLKKQVQ | 
    1100:
    ELKSRLESQY | LTSSLHFNGD | FGDEVTSIPD | SESNLDQNCL | SRCSTEIFSE | 
    1150:
    ASWEQVDKQD | TEMTRWLPDH | LAAHCYACDS | AFWLASRKHH | CRNCGNVFCS | 
    1198:
    SCCNQKVPVP | SQQLFEPSRV | CKSCYSSLHP | TSSSIDLELD | KPIAATSN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    MIM:
    UniGene:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Myotubularin-related protein 3
    ELISA Kit for Human Myotubularin-related protein 3
    ELISA Kit for Human Myotubularin-related protein 3
    CLIA Kit for Human Myotubularin-related protein 3
    CLIA Kit for Human Myotubularin-related protein 3
    CLIA Kit for Human Myotubularin-related protein 3
    Polyclonal Antibody for Human Myotubularin-related protein 3
    Polyclonal Antibody for Human Myotubularin-related protein 3
    Polyclonal Antibody for Human Myotubularin-related protein 3
    Monoclonal Antibody for Human Myotubularin-related protein 3
    Monoclonal Antibody for Human Myotubularin-related protein 3
    Monoclonal Antibody for Human Myotubularin-related protein 3
    Protein for Human Myotubularin-related protein 3
    Protein for Human Myotubularin-related protein 3
    Protein for Human Myotubularin-related protein 3

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "FYVE-DSP1, a dual-specificity protein phosphatase containing an FYVE domain."
      Zhao R. , Qi Y. , Zhao Z.J.
      Biochem. Biophys. Res. Commun.270:222-229(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE (ISOFORMS A; B AND C);CHARACTERIZATION;CATALYTIC ACTIVITY;FUNCTION
    2. 2.
      "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
      Nagase T. , Ishikawa K. , Nakajima D. , Ohira M. , Seki N. , Miyajima N. , Tanaka A. , Kotani H. , Nomura N. , Ohara O.
      DNA Res.4:141-150(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM B)
      tissue: Brain.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM B)
    4. 4.
      "The DNA sequence of human chromosome 22."
      Dunham I. , Hunt A.R. , Collins J.E. , Bruskiewich R. , Beare D.M. , Clamp M. , Smink L.J. , Ainscough R. , Almeida J.P. , Babbage A.K. , Bagguley C. , Bailey J. , Barlow K.F. , Bates K.N. , Beasley O.P. , Bird C.P. , Blakey S.E. , Bridgeman A.M. , more...
      Nature402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS B AND C)
    7. 7.
      "Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human."
      Laporte J. , Blondeau F. , Buj-Bello A. , Tentler D. , Kretz C. , Dahl N. , Mandel J.-L.
      Hum. Mol. Genet.7:1703-1712(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 374-578
    8. 8.
      "A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast."
      Laporte J. , Hu L.-J. , Kretz C. , Mandel J.-L. , Kioschis P. , Coy J. , Klauck S.M. , Poutska A. , Dahl N.
      Nat. Genet.13:175-182(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 381-463
    9. 9.
      "Characterization of MTMR3. an inositol lipid 3-phosphatase with novel substrate specificity."
      Walker D.M. , Urbe S. , Dove S.K. , Tenza D. , Raposo G. , Clague M.J.
      Curr. Biol.11:1600-1605(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF CYS-413;CATALYTIC ACTIVITY;SUBCELLULAR LOCATION
    10. 10.
      "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
      Cantin G.T. , Yi W. , Lu B. , Park S.K. , Xu T. , Lee J.-D. , Yates J.R. III
      J. Proteome Res.7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-647;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-633; SER-647 AND THR-731;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    12. 12.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] LEU-221
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