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Index > Protein center > Muc2(Gene name) > Rat
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  • Muc2 (Gene name),
  • Mucin-2 (Protein name ),  MUC2_RAT from NCBI database.
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  • Antigen Annotation
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  • Gene name:
    Muc2;
    Protein name:
    Mucin-2(MUC-2);
    Alternative:
    Intestinal mucin-2;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homotrimer; disulfide-linked. Dimerizes in the endoplasmic reticulum via its C-terminal region and polymerizes via its N-terminal region by disulfide-linked trimerization. Interacts with FCGBP (By similarity). Interacts with AGR2; disulfide-linked.
    Function:
    Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer.
    Subcellular Location:
    Secreted In the intestine, secreted into the inner and outer mucus layers.
    Protein Attributes:
    Sequence length:
    1513
    Sequence:
    50:
    MGLPLARLVA | VCLVLALAKG | LELQKEARSR | NHVCSTWGDF | HYKTFDGDVF | 
    100:
    RFPGLCDYNF | ASDCRDSYKE | FAVHLKRGLD | KAGGHSSIES | VLITIKDDTI | 
    150:
    YLTHKLAVVN | GAMVSTPHYS | SGLLIEKNDA | YTKVYSRAGL | SLMWNREDAL | 
    200:
    MVELDGRFQN | HTCGLCGDFN | GMQANNEFLS | DGIRFSAIEF | GNMQKINKPE | 
    250:
    VVCEDPEEVQ | EPESCSEHRA | ECERLLTSTA | FEDCQARVPV | ELYVLACMHD | 
    300:
    RCQCPQGGAC | ECSTLAEFSR | QCSHAGGRPE | NWRTASLCPK | KCPGNMVYLE | 
    350:
    SGSPWLDTCS | HLEVSSLCEE | HYMDGCFCPE | GTVYDDITGS | GCIPVSQCHC | 
    400:
    KLHGHLYMPG | QEITNDCEQC | VCNAGRWMCK | DLPCPETCAL | EGGSHITTFD | 
    450:
    GKKFTFHGDC | YYVLTKTKYN | DSYALLGELA | SCGSTDKQTC | LKTVVLLTDN | 
    500:
    KKNVVAFKSG | GSVLLNEMEV | SLPHVAASFS | IFKPSSYHIV | VNTMFGLRLQ | 
    550:
    IQLVPVMQLF | VTLDQSAQGQ | VQGLCGNFNG | LESDDFMTSG | GMVEATGAGF | 
    600:
    ANTWKAQSSC | HDKLDWLDDP | CPLNIESANY | AEHWCSLLKR | SETPFARCHL | 
    650:
    AVDPTEYYKR | CKYDTCNCQN | NEDCMCAALS | SYARACAAKG | VMLWGWRESV | 
    700:
    CNKDVHACPS | SQIFMYNLTT | CQQTCRSISE | GDTHCLKGFA | PVEGCGCPDH | 
    750:
    TFMDEKGRCV | PLSKCSCYHH | GLYLEAGDVI | LRQEERCICR | NGRLQCTQVK | 
    800:
    LIGHTCLSPQ | ILVDCNNLTA | LAIREPRPTS | CQTLVARYYH | TECISGCVCP | 
    850:
    DGLLDNGRGG | CVVEDECPCI | HNKQFYDSGK | SIKLDCNNTC | TCQKGRWECT | 
    900:
    RYACHSTCSI | YGSGHYITFD | GKHYDFDGHC | SYVAVQDYCG | QNSTGSFSII | 
    950:
    TENVPCGTTG | VTCSKAIKIF | IGGTELKLVD | KHRVVKQLEE | GHHVPFITRE | 
    1000:
    VGLYLVVEVS | SGIIVIWDKK | TTIFIKLDPS | YKGNVCGLCG | NFDDQTKNDF | 
    1050:
    TTRDHMVVAS | ELDFGNSWKE | ASTCPDVSHN | PDPCSLNPHR | RSWAEKQCSI | 
    1100:
    IKSDVFLACH | GKVDPTVFYD | ACVHDSCSCD | TGGDCECFCS | AVASYAQECT | 
    1150:
    KAEACVFWRT | PDLCPVFCDY | YNPPDECEWH | YEPCGNRSFE | TCRTLNGIHS | 
    1200:
    NISVSYLEGC | YPRCPEDRPI | YDEDLKKCVS | GDKCGCYIED | TRYPPGGSVP | 
    1250:
    TDEICMSCTC | TNTSEIICRP | DEGKIINQTQ | DGIFCYWETC | GSNGTVEKHF | 
    1300:
    EICVSSTLSP | TSMTSFTTTS | TPISTTPIST | TITTTSATAT | TTVPCCFWSD | 
    1350:
    WINNNHPTSG | NGGDRENFEH | VCSAPENIEC | RAATDPKLDW | TELGQKVQCN | 
    1400:
    VSEGLICNNE | DQYGTGQFEL | CYDYEIRVNC | CFPMEYCLST | VSPTTSTPIS | 
    1450:
    STPQPTSSPT | TLPTTSPLTS | SATSPTTSHI | TSTVSPTTSP | TTSTTSPTTS | 
    1500:
    PTTSTTSPTT | STTSPTPSPT | TSTTSPTPSP | TTSTTSPTPS | PTTSTTSPTT | 
    1513:
    SPITSPTTST | TSP
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat MUC-2
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    ELISA Kit for Rat MUC-2
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    ELISA Kit for Rat MUC-2
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    ELISA Kit for Rat MUC-2
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    E0705r
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    96T
    CLIA Kit for Rat MUC-2
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    Packing:
    96T
    CLIA Kit for Rat MUC-2
    Cat.:
    U0705m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat MUC-2
    Cat.:
    U0705h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat MUC-2
    Cat.:
    U0705r
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    Packing:
    96T
    Polyclonal Antibody for Rat MUC-2
    Cat.:
    P0705Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat MUC-2
    Polyclonal Antibody for Rat MUC-2
    Cat.:
    P0705Rb-m
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    Packing:
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    Polyclonal Antibody for Rat MUC-2
    Cat.:
    P0705Rb-r
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat MUC-2
    Monoclonal Antibody for Rat MUC-2
    Monoclonal Antibody for Rat MUC-2
    Monoclonal Antibody for Rat MUC-2
    Protein for Rat MUC-2
    Protein for Rat MUC-2
    Protein for Rat MUC-2
    Protein for Rat MUC-2

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    References
    1. 1.
      "Molecular cloning of the amino-terminal region of a rat MUC 2 mucin gene homologue. Evidence for expression in both intestine and airway."
      Ohmori H. , Dohrman A.F. , Gallup M. , Tsuda T. , Kai H. , Gum J.R. Jr. , Kim Y.S. , Basbaum C.B.
      J. Biol. Chem.269:17833-17840(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Intestine.
    2. 2.
      "Susceptibility of the cysteine-rich N-terminal and C-terminal ends of rat intestinal mucin Muc 2 to proteolytic cleavage."
      Khatri I.A. , Forstner G.G. , Forstner J.F.
      Biochem. J.331:323-330(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-36
      tissue: Intestinal epithelium.
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