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Index > Protein center > Myocd(Gene name) > Rat
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  • Myocd (Gene name),
  • Myocardin (Protein name ),  MYCD_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    Myocd(Mycd);
    Protein name:
    Myocardin;
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homodimer. Interacts with MLLT7/FOXO4. Interacts with SRF, its association does not depend on specific DNA sequences for ternary complex formation (By similarity). Interacts (via C-terminal) with EP300 (via the CREB-binding domain). Interacts with HDAC4 and HDAC5 (By similarity). Interacts with MEF2C.
    Function:
    Smooth muscle cells (SM) and cardiac muscle cells-specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes (By similarity). Plays a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage (myogenesis).
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    938
    Sequence:
    50:
    MTLLGSEHSL | LIRRKFRSVL | QLRLQQRRTQ | EQLANQGLIP | PLKSPTEFHD | 
    100:
    PRKKLDSAKT | EDSLRRKVRN | RSDRASLVNM | HILQASTAER | SIPTAQMKLK | 
    150:
    RARLADDLNE | KIALRPGPLE | LVEKNILPMD | SSVKEAIKGT | EVSLSKAADA | 
    200:
    FAFEDDSSRD | GLSPDQARSE | DPQGSGGSTP | DIKSTEAPLA | GPLDTIQDLT | 
    250:
    PGSESDKNDT | ASQLSNQSDS | GKQVLGPLST | PIPVHTAVKS | KSLGDSKNRH | 
    300:
    KKPKDPKPKV | KKLKYHQYIP | PDQKAEKSPP | PMDSAYARLL | QQQQLFLQLQ | 
    350:
    ILSQQQQQQQ | QQQQQQQQQQ | QQQRFSYPGM | HQAHLKEPNE | QMTRNPNSSS | 
    400:
    TPLNNTPLSP | VKNSLSGQTG | VSSLKPGPLP | PNLDDLKVSE | LRQQLRIRGL | 
    450:
    PVSGTKTALV | DRLRPFQDCA | GNPVPNFGDI | TTVTFPVTPN | TLPSYQSSPS | 
    500:
    GFYHFGSTSS | SPPISPASSD | LSAAGSLPDT | FTDASPGFGL | HASPVPACTD | 
    550:
    ESLLSSLNGG | SGPSEPDGLD | SEKDKMLVEK | QKVINQLTWK | LRQEQRQVEE | 
    600:
    LRMQLQKQKS | GCNDQKPLPF | LATTIKQEDV | SSCPFAAQQA | SGKGQGHSSD | 
    650:
    SPPPACETAQ | LLPHCVESSG | QTHVLSSTFL | SPQCSPQHSP | LGTLKSPQHI | 
    700:
    SLPPSPNNHY | FLASSSGAQR | ENHGVSSPNS | SQGCAQMTGL | QSSDKVGPTF | 
    750:
    SIPSPTFPKS | SPTVPEITQP | PSYEDAVKQQ | MTRSQQMDEL | LDVLIESGEM | 
    800:
    PADAREDHSC | LQKIPKIPGS | SCSPTTILPK | SSASFEQASS | GGQISFDHYA | 
    850:
    TDSEEHLEVL | LNSHSPIGKV | SDVTLLKIGS | EEPPFDGIMD | GFPGKAAEDL | 
    900:
    FSAHELLPGP | LSPMHTQLSP | PSVDSSGLQL | SFTESPWETM | EWLDLTPPSS | 
    938:
    TPGFSNLTSS | GPSIFNIDFL | DVTDLNLNSP | MDLHLQQW
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Myocardin
    Cat.:
    E0535h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Myocardin
    Cat.:
    E0535p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Myocardin
    Cat.:
    E0535r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Rat Myocardin
    Cat.:
    E0535m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Myocardin
    Cat.:
    U0535h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Myocardin
    Cat.:
    U0535p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Myocardin
    Cat.:
    U0535r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Myocardin
    Cat.:
    U0535m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Myocardin
    Cat.:
    P0535Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Myocardin
    Cat.:
    P0535Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Myocardin
    Cat.:
    P0535Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Myocardin
    Monoclonal Antibody for Rat Myocardin
    Monoclonal Antibody for Rat Myocardin
    Monoclonal Antibody for Rat Myocardin
    Monoclonal Antibody for Rat Myocardin
    Protein for Rat Myocardin
    Protein for Rat Myocardin
    Protein for Rat Myocardin
    Protein for Rat Myocardin

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    References
    1. 1.
      "Myocardin: a component of a molecular switch for smooth muscle differentiation."
      Chen J. , Kitchen C.M. , Streb J.W. , Miano J.M.
      J. Mol. Cell. Cardiol.34:1345-1356(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Aorta.
    2. 2.
      "Myocardin is a key regulator of CArG-dependent transcription of multiple smooth muscle marker genes."
      Yoshida T. , Sinha S. , Dandre F. , Wamhoff B.R. , Hoofnagle M.H. , Kremer B.E. , Wang D.-Z. , Olson E.N. , Owens G.K.
      Circ. Res.92:856-864(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 251-399
      tissue: Aorta.
    3. 3.
      "Myocardin is a master regulator of smooth muscle gene expression."
      Wang Z. , Wang D.-Z. , Pipes G.C. , Olson E.N.
      Proc. Natl. Acad. Sci. U.S.A.100:7129-7134(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;MUTAGENESIS OF ILE-534; LEU-537 AND LEU-541
    4. 4.
      "Expression and functional activity of four myocardin isoforms."
      Imamura M. , Long X. , Nanda V. , Miano J.M.
      Gene464:1-10(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY OF ISOFORMS
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