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Index > Protein center > MYLK2(Gene name) > Human
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  • MYLK2 (Gene name),
  • Myosin light chain kinase 2, skeletal/cardiac muscle (Protein name ),  MYLK2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    MYLK2;
    Protein name:
    Myosin light chain kinase 2, skeletal/cardiac muscle(MLCK2);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    May interact with centrin.
    Function:
    Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N-terminus of a myosin light chain.
    Subcellular Location:
    Cytoplasm Colocalizes with phosphorylated myosin light chain (RLCP) at filaments of the myofibrils.
    Protein Attributes:
    Sequence length:
    596
    Sequence:
    50:
    MATENGAVEL | GIQNPSTDKA | PKGPTGERPL | AAGKDPGPPD | PKKAPDPPTL | 
    100:
    KKDAKAPASE | KGDGTLAQPS | TSSQGPKGEG | DRGGGPAEGS | AGPPAALPQQ | 
    150:
    TATPETSVKK | PKAEQGASGS | QDPGKPRVGK | KAAEGQAAAR | RGSPAFLHSP | 
    200:
    SCPAIISSSE | KLLAKKPPSE | ASELTFEGVP | MTHSPTDPRP | AKAEEGKNIL | 
    250:
    AESQKEVGEK | TPGQAGQAKM | QGDTSRGIEF | QAVPSEKSEV | GQALCLTARE | 
    300:
    EDCFQILDDC | PPPPAPFPHR | MVELRTGNVS | SEFSMNSKEA | LGGGKFGAVC | 
    350:
    TCMEKATGLK | LAAKVIKKQT | PKDKEMVLLE | IEVMNQLNHR | NLIQLYAAIE | 
    400:
    TPHEIVLFME | YIEGGELFER | IVDEDYHLTE | VDTMVFVRQI | CDGILFMHKM | 
    450:
    RVLHLDLKPE | NILCVNTTGH | LVKIIDFGLA | RRYNPNEKLK | VNFGTPEFLS | 
    500:
    PEVVNYDQIS | DKTDMWSMGV | ITYMLLSGLS | PFLGDDDTET | LNNVLSGNWY | 
    550:
    FDEETFEAVS | DEAKDFVSNL | IVKDQRARMN | AAQCLAHPWL | NNLAEKAKRC | 
    596:
    NRRLKSQILL | KKYLMKRRWK | KNFIAVSAAN | RFKKISSSGA | LMALGV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    MIM:
    Pfam:
    SMR:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human MLCK2
    ELISA Kit for Human MLCK2
    ELISA Kit for Human MLCK2
    ELISA Kit for Human MLCK2
    ELISA Kit for Human MLCK2
    CLIA Kit for Human MLCK2
    CLIA Kit for Human MLCK2
    CLIA Kit for Human MLCK2
    CLIA Kit for Human MLCK2
    CLIA Kit for Human MLCK2
    Polyclonal Antibody for Human MLCK2
    Polyclonal Antibody for Human MLCK2
    Polyclonal Antibody for Human MLCK2
    Polyclonal Antibody for Human MLCK2
    Polyclonal Antibody for Human MLCK2
    Monoclonal Antibody for Human MLCK2
    Monoclonal Antibody for Human MLCK2
    Monoclonal Antibody for Human MLCK2
    Monoclonal Antibody for Human MLCK2
    Monoclonal Antibody for Human MLCK2
    Protein for Human MLCK2
    Protein for Human MLCK2
    Protein for Human MLCK2
    Protein for Human MLCK2
    Protein for Human MLCK2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The overall pattern of cardiac contraction depends on a spatial gradient of myosin regulatory light chain phosphorylation."
      Davis J.S. , Hassanzadeh S. , Winitsky S. , Lin H. , Satorius C. , Vemuri R. , Aletras A.H. , Wen H. , Epstein N.D.
      Cell107:631-641(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;VARIANTS CMH VAL-87 AND GLU-95
      tissue: Skeletal muscle.
    2. 2.
      "Full-length sequencing of 100 cDNA clones from human adult skeletal muscle."
      Stanchi F. , Lanfranchi G.
      Submitted (2000-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Skeletal muscle.
    3. 3.
      "The DNA sequence and comparative analysis of human chromosome 20."
      Deloukas P. , Matthews L.H. , Ashurst J.L. , Burton J. , Gilbert J.G.R. , Jones M. , Stavrides G. , Almeida J.P. , Babbage A.K. , Bagguley C.L. , Bailey J. , Barlow K.F. , Bates K.N. , Beard L.M. , Beare D.M. , Beasley O.P. , Bird C.P. , Blakey S.E. , more...
      Nature414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Muscle.
    5. 5.
      "Structural features of the complexes formed by Scherffelia dubia centrin."
      Radu L. , Miron S. , Durand D. , Assairi L. , Blouquit Y. , Charbonnier J.B.
      Submitted (2011-01) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF 566-587 IN COMPLEX WITH CENTRIN;SUBUNIT
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